A Spine Robotic-Assisted Navigation System for Pedicle Screw Placement. J Vis Exp. 2020 May 11;(159): Authors: Chen HY, Xiao XY, Chen CW, Chou HK, Sung CY, Lin FH, Chen PQ, Wong TH Abstract Pedicle screw implantation has excellent treatment effects and is often used by surgeons in spinal fusion surgery. However, due to the complexity of human body anatomy, this surgical procedure is difficult and challenging, especially in minimally invasive surgery...
Surface Mapping of Earth-like Exoplanets using Single Point Light Curves. J Vis Exp. 2020 May 10;(159): Authors: Fan S, Yung YL Abstract Spatially resolving exoplanet features from single-point observations is essential for evaluating the potential habitability of exoplanets. The ultimate goal of this protocol is to determine whether these planetary worlds harbor geological features and/or climate systems. We present a method of extracting information...
Simultaneous Quantification of Selected Kynurenines Analyzed by Liquid Chromatography-Mass Spectrometry in Medium Collected from Cancer Cell Cultures. J Vis Exp. 2020 May 09;(159): Authors: Sadok I, Rachwał K, Staniszewska M Abstract The kynurenine pathway and the tryptophan catabolites called kynurenines have received increased attention for their involvement in immune regulation and cancer biology. An in vitro cell culture assay is often used to...
Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model. J Vis Exp. 2020 May 06;(159): Authors: Pinamont WJ, Yoshioka NK, Young GM, Karuppagounder V, Carlson EL, Ahmad A, Elbarbary R, Kamal F Abstract One of the most prevalent joint disorders in the United States, osteoarthritis (OA) is characterized by progressive degeneration of articular cartilage, primarily in the hip and knee joints, which results in significant...
In Situ Detection of Ribonucleoprotein Complex Assembly in the C. elegans Germline using Proximity Ligation Assay. J Vis Exp. 2020 May 05;(159): Authors: Day NJ, Wang X, Voronina E Abstract Understanding when and where protein-protein interactions (PPIs) occur is critical to understanding protein function in the cell and how broader processes such as development are affected. The Caenorhabditis elegans germline is a great model system for studying...
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Azithromycin has lung barrier protective effects in a cell model mimicking ventilator-induced lung injury. ALTEX. 2020 May 19;: Authors: Joelsson JP, Myszor IT, Sigurdsson S, Lehmann F, Page C, Gudmundsson GH, Gudjonsson T, Karason S Abstract Azithromycin (AZM) is a broad-spectrum antibiotic widely used to treat infections. AZM has also been shown to have anti-inflammatory and immunomodulatory functions unrelated to its antibacterial activity which contribute...
15h
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Referrals by general dental practitioners and medical practitioners to oral medicine specialists in New Zealand: a study to develop protocol guidelines. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May 21;: Authors: Guan G, Lau J, Yew V, U J, Qu W, Lam J, Polonowita A, Mei L Abstract OBJECTIVE: The aim of this study was to examine the awareness level among general dental practitioners and medical practitioners with regard to common oral mucosal...
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Alternatives to Acid Suppression Treatment for Laryngopharyngeal Reflux. Ann Otol Rhinol Laryngol. 2020 May 25;:3489420922870 Authors: Huestis MJ, Keefe KR, Kahn CI, Tracy LF, Levi JR Abstract OBJECTIVE: Laryngopharyngeal reflux (LPR) and associated symptoms can be refractory to treatment with acid suppressing medication. We investigated the role and evidence for complementary and alternative medicine (CAM) for LPR in this systematic review. ...
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Matched analysis of the prognosis of amelanotic and pigmented melanoma in head and neck. Acta Otolaryngol. 2020 May 23;:1-4 Authors: Guo W, Yin G, Liu H, Duan H, Huang Z, Chen X Abstract Background: The prognosis of mucosal melanoma is poor, and the difference in clinical prognosis between patients with and without pigment needs further study.Aim: To analyze data with head and neck mucosal melanoma, and compare the prognosis of patients with and without...
Dexamethasone delivery for hearing preservation in animal cochlear implant model: continuity, long-term release, and fast release rate. Acta Otolaryngol. 2020 May 23;:1-10 Authors: Lee MY, Kim YC, Jang J, Jung JY, Choi H, Jang JH, Choung YH Abstract Background: Clinically, steroids have been used for hearing preservation both topically and systemically during cochlear implantation.Objective: This study compared steroid efficacy for hearing preservation...
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Difficult to Diagnose: An Unusual Cause of Cavitary Lung Lesion. Am J Case Rep. 2020 May 25;21:e921274 Authors: Norman HE, Davis JM, Kadaria D Abstract BACKGROUND Cavitary lung lesions are commonly identified on thoracic imaging, but typically require further workup for definitive diagnosis. CASE REPORT Here, we present the case of a 40-year-old Middle Eastern male who presented with an unusual cause of cavitary lung lesion with associated pleural mass...
Stenotrophomonas maltophilia: An Emerging Pathogen of the Respiratory Tract. Am J Case Rep. 2020 May 25;21:e921466 Authors: Kanderi T, Shrimanker I, Mansoora Q, Shah K, Yumen A, Komanduri S Abstract BACKGROUND Stenotrophomonas maltophilia has the propensity to cause a plethora of opportunistic infections in humans owing to biofilm formation and antibiotic resistance. It is often seen as a co-organism along with Pseudomonas aeruginosa. CASE REPORT A 70-year-old...
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Exercise training decreases oxidative stress in skeletal muscle of rats with pulmonary arterial hypertension. Arch Physiol Biochem. 2020 May 25;:1-9 Authors: Becker CU, Sartório CL, Campos-Carraro C, Siqueira R, Colombo R, Zimmer A, Belló-Klein A Abstract The effects of exercise training on oxidative stress in gastrocnemius of rats with pulmonary hypertension were studied. Four groups were established: sedentary control (SC), sedentary monocrotaline...
MicroRNA-143 inhibits proliferation and migration of prostate cancer cells. Arch Physiol Biochem. 2020 May 25;:1-7 Authors: Bajhan E, Mansoori B, Mohammadi A, Shanehbandi D, Khaze Shahgoli V, Baghbani E, Hajiasgharzadeh K, Baradaran B Abstract Background: Prostate cancer (PC) is one of the most prevalent types of malignancies in males. Here, we replaced the miRNA-143 in PC cells by using a vector-based miRNA-143 transfection approach.Materials and methods:...
The effects of microRNA-126 reduced inflammation and apoptosis of diabetic nephropathy through PI3K/AKT signalling pathway by VEGF. Arch Physiol Biochem. 2020 May 25;:1-10 Authors: Lou Z, Li Q, Wang C, Li Y Abstract Gene expression microarray and reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used to measure the expression of miR-126. In model of diabetic nephropathy, we demonstrated that miR-126 expression was down-regulated,...
Identification of amyloid antibodies for Alzheimer disease - immunotherapy. Arch Physiol Biochem. 2020 May 25;:1-8 Authors: Huwait EA, Baghallab IM, Glabe CG, Abulnaja KO, Kumosani TA, Moselhy SS Abstract The current study identified the specific antibodies that recognise amyloid protein for Alzheimer disease - immunotherapy. The immune-selection of random sequences from a phage display library and sequencing to obtain the random 12 amino acids peptide...
Determination of carnitine ester profile in the children with type 1 diabetes: a valuable step towards a better management. Arch Physiol Biochem. 2020 May 24;:1-6 Authors: Rahmani P, Abolhasani R, Heidari G, Mohebi A, Sayarifard F, Rabbani A, Vafaei N, Lotfi J Abstract Objective: This study is designed to investigate the levels of carnitine and acylcarnitines (ACs) in the children with diabetes type 1 compared to the healthy subjects.Methods: Forty-two...
Allopurinol and valproic acid improve cardiac triglyceride and Na+-K+-ATPase activity independent of circulating aldosterone in female rats with glucose intolerance. Arch Physiol Biochem. 2020 May 23;:1-7 Authors: Adegoke TE, Sabinari IW, Usman TO, Abdulkareem TO, Michael OS, Adeyanju OA, Dibia C, Omotoye OO, Oyabambi AO, Olatunji LA Abstract Context: Studies have shown that cardiac triglyceride accumulation and impaired Na+-K+-ATPase activity are linked...
Variation in the expression level of MALAT1, MIAT and XIST lncRNAs in coronary artery disease patients with and without type 2 diabetes mellitus. Arch Physiol Biochem. 2020 May 23;:1-8 Authors: Sohrabifar N, Ghaderian SMH, Alipour Para S, Ghaedi H, Jafari H Abstract Background: The MALAT1, MIAT, and XIST long noncoding RNAs (lncRNAs) participate in the pathogenesis of complex diseases and also serve as diagnostic markers. The study aimed to assess their...
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Cytogenotoxic evaluation of the acetonitrile extract, citrinin and dicitrinin-A from Penicillium citrinum. Drug Chem Toxicol. 2020 May 25;:1-10 Authors: de Oliveira Filho JWG, Andrade TJADS, de Lima RMT, Silva DHS, Dos Reis AC, Santos JVO, de Meneses APM, de Carvalho RM, da Mata AMO, de Alencar MVOB, Dias ACS, da Silva FCC, Islam MT, Clark CCT, Sousa JMCE, Melo-Cavalcante AAC Abstract Endophytic fungi are promising sources of bioactive substances; however,...
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BIO 300: a promising radiation countermeasure under advanced development for acute radiation syndrome and the delayed effects of acute radiation exposure. Expert Opin Investig Drugs. 2020 May;29(5):429-441 Authors: Singh VK, Seed TM Abstract INTRODUCTION: There are no radioprotectors currently approved by the United States Food and Drug Administration (US FDA) for either the hematopoietic acute radiation syndrome (H-ARS) or for the acute radiation gastrointestinal...
Pamrevlumab for the treatment of idiopathic pulmonary fibrosis. Expert Opin Investig Drugs. 2020 May 23;: Authors: Sgalla G, Franciosa C, Simonetti J, Richeldi L Abstract INTRODUCTION: The two available therapies for idiopathic pulmonary fibrosis (IPF), pirfenidone and nintedanib, slow down but do not halt IPF progression. Hence, in the last few years, several agents with specific molecular targets have been investigated to find a cure for IPF. Pamrevlumab,...
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Amoebic toxic megacolon with poly-helminthic coinfection: Case presentation and review of intestinal polyparasitic infections. Int J Surg Case Rep. 2020 May 11;71:151-154 Authors: Yusof S, Zhao Y, Quah J, Eu CEE, Wang LM Abstract INTRODUCTION: Intestinal parasitic infections are a health burden to developing countries, but can also become more prevalent worldwide, even in developed countries, with the advent of globalization. While most of these infections...
A metastatic distal-type epithelioid sarcoma: Case report and review. Int J Surg Case Rep. 2020 May 16;71:144-146 Authors: Regalbuto A, Tudosie A, Klenotic E Abstract INTRODUCTION: Epithelioid sarcoma is known as one of the rarest types of sarcomas and was identified as its own diagnosis by Dr. Franz Enzinger in 1970 after his realization of its massive overlap with many other diseases. This tumor has an aggressive clinical course with high recurrence...
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Lung adenocarcinoma observed within a peripheral cavitary lesion using an ultrathin bronchoscope. Jpn J Clin Oncol. 2020 May 25;: Authors: Sumi T, Sawai T, Shijubou N, Yamada Y, Nakata H, Mori Y, Takahashi H PMID: 32448892 [PubMed - as supplied by publisher]
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Levodopa Facilitates Prefrontal Cortex Activation During Dual Task Walking in Parkinson Disease. Neurorehabil Neural Repair. 2020 May 25;:1545968320924430 Authors: Orcioli-Silva D, Vitório R, Nóbrega-Sousa P, da Conceição NR, Beretta VS, Lirani-Silva E, Gobbi LTB Abstract Background. Although dopaminergic medication improves dual task walking in people with Parkinson disease (PD), the underlying neural mechanisms are not yet fully understood. As prefrontal...
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Higher Incidence of Syphilis among Patients with HIV Infection: Population Study using Surveillance Data of Tokyo, Japan. Tohoku J Exp Med. 2020;251(1):39-46 Authors: Sugishita Y, Kurita J, Sugawara T, Ohkusa Y Abstract In Japan, the reported cases of syphilis have been increasing since 2011 especially in large cities such as Tokyo. The objective of this study was to evaluate the risk of HIV infection for syphilis co-infection on the population of Tokyo,...
Protease Inhibitors: Candidate Drugs to Inhibit Severe Acute Respiratory Syndrome Coronavirus 2 Replication. Tohoku J Exp Med. 2020;251(1):27-30 Authors: Yamaya M, Nishimura H, Deng X, Kikuchi A, Nagatomi R Abstract The number of patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly increased, although the WHO declared a pandemic. However, drugs that function against SARS-CoV-2 have not been established. SARS-CoV-2...
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Delayed development of spinal subdural hematoma following cranial trauma: A case report and review of the literature. World Neurosurg. 2020 May 22;: Authors: Hsieh JK, Colby S, Nichols D, Kondylis E, Liu JKC Abstract BACKGROUND: Spinal subdural hematomas (SDHs) have been reported as a result of direct trauma or from iatrogenic causes associated with coagulopathies. Extremely rare are spinal SDHs that are found after the development of acute intracranial...
Impact of the COVID-19 Pandemic on Neurosurgical Practice at an Academic Tertiary Referral Center: A Comparative Study. World Neurosurg. 2020 May 22;: Authors: Noureldine MHA, Pressman E, Krafft PR, Greenberg MS, Agazzi S, van Loveren H, Alikhani P Abstract BACKGROUND: Neurosurgical services are affected by the COVID-19 pandemic, and several departments reported their experiences and responses to the COVID-19 crisis in an attempt to provide insights...
Meta-analysis with Trial Sequential Analysis on the Efficacy and Safety of Erythropoietin in Traumatic Brain Injury: A New Paradigm. World Neurosurg. 2020 May 22;: Authors: Katiyar V, Chaturvedi A, Sharma R, Gurjar HK, Goda R, Singla R, Ganeshkumar A PMID: 32450313 [PubMed - as supplied by publisher]
Letter: Changes to neurosurgery resident education following onset of the COVID-19 pandemic. World Neurosurg. 2020 May 22;: Authors: Pennington Z, Lubelski D, Khalafallah A, Ehresman J, Sciubba DM, Witham TF, Huang J Abstract BACKGROUND: The COVID-19 pandemic has led to the postponement of a large proportion of neurosurgical cases with an accordant radical change in resident experiences. As residents rely upon operative exposure and in-person didactic...
Service and training during the COVID-19 pandemic: Perspectives from a neurosurgical center in the Philippines. World Neurosurg. 2020 May 22;: Authors: Legaspi GD, Omar AT, Baticulon RE, Salonga AEM, Gaddi MJS, Hong MAC, Seng KS, Khu KJO PMID: 32450311 [PubMed - as supplied by publisher]
An Australian Response to the COVID-19 Pandemic and its Implications on the Practice of Neurosurgery. World Neurosurg. 2020 May 22;: Authors: Antony J, James WT, Neriamparambil AJ, Barot DD, Withers T Abstract OBJECTIVE: This study was designed to assess the impact of public health policy in Australia in response to the Coronavirus disease 2019 (COVID-19) pandemic on the delivery of neurosurgical services. Being essential services, we postulated that...
Telemedicine for Outpatient Neurosurgical Oncology Care: Lessons Learned for the Future During the COVID-19 Pandemic. World Neurosurg. 2020 May 22;: Authors: Daggubati LC, Eichberg DG, Ivan ME, Hanft S, Mansouri A, Komotar RJ, D'Amico RS, Zacharia BE Abstract BACKGROUND: The 2019 Coronavirus pandemic has drastically disrupted the delivery of Neurosurgical care, especially for the already at-risk neuro-oncology population. The sudden change to clinic...
Feasibility of CaO-SiO2-P2O5-B2O3 Bioactive Glass Ceramic Cage in Anterior Cervical Discectomy and Fusion. World Neurosurg. 2020 May 22;: Authors: Park S, Lee DH, Seo J, Kim KJ, Lee SK, Park JH, Cho JH, Park JW, Hwang CJ, Yang JJ, Lee CS Abstract OBJECTIVE: CaO-SiO2-P2O5-B2O3 bioactive glass ceramic (BGC) is known to chemically bond with bones by forming a hydroxyapatite layer and inducing osteoblastic differentiation. The present study was conducted...
Intracranial Leiomyoma Associated with Epstein-Barr Virus: a cerebellopontine angle mass presenting with trigeminal neuralgia. World Neurosurg. 2020 May 22;: Authors: Sadeh M, Chaudhry NS, Selner A, Behbahani M, Valyi-Nagy T, Atwal G PMID: 32450307 [PubMed - as supplied by publisher]
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Salvianolic acid B attenuates epithelial-mesenchymal transition in renal fibrosis rats through activating Sirt1-mediated autophagy. Biomed Pharmacother. 2020 May 22;128:110241 Authors: He Y, Lu R, Wu J, Pang Y, Li J, Chen J, Liu B, Zhou Y, Zhou J Abstract Renal fibrosis is a kind of progressive kidney disease leading to end-stage renal damage. Epithelial-mesenchymal transition (EMT) is one of the crucial features of renal fibrosis. Salvianolic acid...
Long-term arsenite exposure decreases autophagy by increased release of Nrf2 in transformed human keratinocytes. Sci Total Environ. 2020 May 13;734:139425 Authors: Wu J, Ni Y, Yang Q, Mao J, Zhu X, Tao S, Kato K, Zhang J, Wang D, Yamanaka K, An Y Abstract Autophagy dysfunction in arsenite toxicity plays critical roles in cancer development and progression. However, the precise mechanisms of arsenite-induced skin cancer by blocking autophagy remain...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,