A gap from a missing tooth can make the other teeth next to it move or drift into the space. Our pearly whites play a crucial role in our overall well-being, however, there can be times when your dentist might recommend a tooth extraction.
The health concerns may be obvious, but the culprits less so. The programme Why It Matters uncovers the hidden sugars that leave children particularly vulnerable.
Abstracts concerning indolent and aggressive lymphoma and multiple myeloma with clinical relevance from the ASCO 2017 meeting are discussed.
Personalized medicine is rapidly changing the daily routine for the diagnostic work-up and treatment of cancer patients. Several clinical studies and programs are ongoing worldwide to implement personalized anticancer therapies particularly for relapsed/refractory malignancies. On 28 October 2016, the first meeting of the Austrian Expert Panel for Molecular Cancer Profiling was held in Salzburg with the purpose to identify clinical studies and registry programs focusing on comprehensive molecular tumor profiling and personalized cancer therapies in Austria. Representatives of the four Austrian academic centers and from two teaching hospitals were invited to present and debate the current status, challenges, and perspectives in precision oncology. To date, three clinical programs are recruiting patients with relapsed/refractory malignancies in Austria: the ONCO-T-PROFILE program at the Medical University of Innsbruck, the platform MONDTI at the Medical University of Vienna, and the ICT (Individualized Cancer Treatment) phase II trial at the Medical University of Graz. The aim of both research programs and the phase II trial is to investigate the efficacy of molecular profile-based personalized therapies in refractory and relapsed metastatic cancer patients. Furthermore, in cooperation with the AGMT (Study Group of Medical Tumor Therapy), a clinical registry will be established to monitor and to analyze the benefit of molecular profiling in real life.
The Alberta Government and the Alberta Dental Association and College announced a new optional dental fee guide on Wednesday in a bid to help lower-income households and seniors afford dental care. "People are still paying the same on premiums, the only one who's winning are the insurance companies," said Dr. Frank Neves, dentist at Bright Dental.
It is contentious whether potentially inappropriate prescribing (PIP) is predominantly a phenomenon of late life or whether it has its origins in early old age. This study examined the pattern of PIP in an early old-aged population over 5 years.
Secondary data analysis of a population-based primary care cohort, of patients aged 60–74 years. Medication data were extracted from electronic patient records in addition to information on comorbidities and demographics. Explicit START criteria (PPOs) and STOPP criteria (PIMs) were used to identify PIP. Generalised estimating equations were used to describe trends in PIP over time and adjusted for age, gender and number of medicines.
A total of 978 participants (47.8%) aged 60–74 years were included from the cohort. At baseline, PPOs were detected in 31.2% of patients and PIMs were identified in 35.6% at baseline. Prevalence of PPOs and PIMs increased significantly over time (OR 1.08, 95% CI 1.07; 1.09 and OR 1.04, 95% CI 1.0; 1.06, respectively). A higher number of medicines and new diagnoses were associated with the increasing trend in both PPO and PIM prevalence observed over time, independent of PPOs and PIMs triggered by drug combinations.
Potentially inappropriate prescribing is highly prevalent among early old-aged people in primary care and increases as they progress to more advanced old age, suggesting that routine application of STOPP/START criteria in this population would significantly improve medication appropriateness.
Sleep affects adolescents in various ways. However, the effects of multiple factors on sleep hygiene remain unclear. A comprehensive assessment of the effects of life habits on sleep in high-school students was conducted.
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In Germany, over-the-counter (OTC) drugs are normally reimbursed up to the age of 12 years only. The aim of this study was to analyse prices of over-the-counter drugs used by adolescents in Germany and their a...
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Performing a tick check after visiting nature is considered the most important preventive measure to avoid contracting Lyme disease. Checking the body for ticks after visiting nature is the only measure that c...
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Couples HIV counseling and testing is essential for combination HIV prevention, but its uptake remains very low. We aimed to evaluate factors associated with couples HIV counseling uptake in India, Georgia and...
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Associations between education and obesity have been consistently reported among women in developed countries, but few studies have considered the influence of marital status and husbands' education. This stud...
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Substantial evidence suggests that weight gain in early life is associated with increased adiposity and other metabolic disorders later in life. It is, however, unknown whether physical activity (PA) may modif...
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We aimed to systematically review published literature to assess study-level sources of heterogeneity in participation and retention for randomized controlled trials (RCTs) conducted exclusively at safety-net institutions, which are primary sources of care for underserved populations.
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In response to Jain and Shetty,1 we would like to apologise for the errors in our paper that was published in your journal recently.2 The sentence: "These authors all used four-hole sliding plates to fix the mandibular bony segments" should have read: "These authors all used four-hole plates to fix the mandibular bony segments". It referred to earlier studies by Abeltins et al,3 Ballon et al,4 and Landes and Ballon,5 in which they all used four-hole plates to fix proximal and distal segments of mandible.
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Recalcitrant chronic rhinosinusitis without polyposis (CRSsP) is a challenging condition to manage as traditional medical therapies and surgery fail to provide satisfactory clinical improvements. Colloidal sil...
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In a blog post that went live Wednesday afternoon, the video-sharing site announced five ways it was strengthening guidelines to stop perverse videos that are trying "to pass as family-friendly." The update to the rules have come after months of speculation on videos aimed at kids that show questionable content - for example one that featured a character similar to Peppa pig , whose teeth are pulled out at the dentist as crying is heard.
To establish whether if Irrigant Activation Techniques (IAT) result in greater intracanal smear layer and debris removal than Conventional Needle Irrigation (CNI).
Six electronic databases were searched to identify scanning-electron-microscopy studies evaluating smear layer and/or debris removal following use of Manual Dynamic Activation (MDA), Passive Ultrasonic Irrigation (PUI), Sonic Irrigation (SI) or Apical Negative Pressure (ANP) IATs in mature permanent teeth. Meta-analyses were performed for each canal segment (coronal, middle, apical and apical 1mm) in addition to subgroup analyses for individual IATs with respect to CNI. Outcomes were presented as Standardised-Mean-Differences (SMD) alongside 95%-Confidence Intervals (95%CI) and chi-squared analysis.
From 252 citations, 16 studies were identified. The meta-analyses demonstrated significant improvements in coronal (SMD:1.15, 95%CI:0.72-1.57 / SMD:0.54, 95%CI:0.29-0.80), middle (SMD:1.30, 95%CI:0.59-2.53 / SMD:0.8, 95%CI:0.58-1.13) and apical thirds (SMD:1.22, 95%CI:0.83-1.62 / SMD:1.86, 95%CI:0.76-2.96) for smear layer and debris removal respectively. In the apical 1mm IATs improved cleanliness; however differences were insignificant (SMD:1.15, 95%CI:-0.47-2.77). Chi-squared analysis revealed heterogeneity scores of 79.3-92.8% and 0.0-93.5% for smear layer and debris removal respectively.
IATs improve intracanal cleanliness across a substantial portion of the canal and therefore their use is recommended throughout root canal preparation. However, current data is too heterogeneous to compare and identify superiority of an individual technique highlighting the need to standardise experimental protocols and develop a more representative research model to investigate the in impact of IATs on clinical outcomes and periapical healing following root canal treatment.
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Dentists agree that brushing your teeth twice a day is essential for oral health. But some people fall victim to bad brushing habits, like skipping hard-to-reach spots and not brushing long enough.
