Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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- Effect of different resin luting cements on the ma...
- Prosthodontic rehabilitation with monolithic, mult...
- Analysis of the golden proportion and width/height...
- Modification of Makzoume vertical dimension record...
- Effect of coloring and sintering on the translucen...
- Aluminum barrier laminate or plastic tube as a dis...
- Marginal discrepancy of noble metal–ceramic fixed ...
- Stress generation in mandibular anterior teeth res...
- A 3D-printed guide for lateral approach sinus graf...
- Diagnostic accuracy of 4 intraoral radiographic te...
- Degree of conversion of resin cement with varying ...
- Esthetic abutment design for angulated screw chann...
- A reflection and analysis about the tools in the a...
- Dopaminergic pathways for bruxism: a way forward?
- Asymmetric bone remodeling in mandibular and maxil...
- The elevated activation of NFκB and AP-1 is correl...
- Four-year outcomes of restored posterior tooth sur...
- Choto Family Dentistry coming
- Halitosis: effect of periodontal treatment
- How does sinus surgery affect topical irrigation d...
- Potential Effect of Leukocyte-Platelet-Rich Fibrin...
- Cancer-related hypercalcemia in oral cancer
- Buccal Mucosal Epithelial Cells Downregulate CTGF ...
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- The End of the Road
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Πέμπτη 16 Νοεμβρίου 2017
Effect of different resin luting cements on the marginal fit of lithium disilicate pressed crowns
Source:The Journal of Prosthetic Dentistry
Author(s): Radek Mounajjed, Thomas J. Salinas, Tomas Ingr, Basel Azar
Statement of problemThe vertical marginal discrepancy of restorations can increase upon cementation, and poor marginal fit can lead to cement dissolution, marginal discoloration, microleakage, and secondary caries. The amount of increase is related to the type of luting cement used, but how lithium disilicate pressed crowns are affected by different resin cements is unclear.PurposeThe purpose of this in vitro study was to compare the effect of using different resin luting cements on the vertical marginal discrepancy of lithium disilicate pressed crowns.Material and methodsA total of 18 intact extracted mandibular third molars were disinfected in a solution of 10% formalin for 7 days and were then prepared to receive a ceramic crown. Impressions were made with polyvinyl siloxane and lithium disilicate pressed crowns made and cemented with 1 of 3 resin luting cements. The marginal discrepancy was measured at 4 points on the finishing line of each tooth, with optical microscopy at ×200 magnification before and after cementation. Statistical analysis was done with the Kruskal-Wallis test to compare the median marginal increase among the 3 groups.ResultsThe least amount of marginal increase after cementation was with Harvard PremiumFlow cement, with an average marginal increase of 42 ±11 μm. RelyX Ultimate cement increased the margins by an average 45 ±29 μm. The highest marginal increase was found in the Enamel Plus HRi preheated composite resin group (116 ±47 μm).ConclusionsThe marginal increase of pressed crowns cemented with preheated composite resin (Enamel Plus HRi) exceeded the clinically acceptable range of marginal discrepancy.
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Prosthodontic rehabilitation with monolithic, multichromatic CAD-CAM complete overdentures in an adolescent patient with ectodermal dysplasia: A clinical report
Source:The Journal of Prosthetic Dentistry
Author(s): Hussain D. Alsayed, Nasser M. Alqahtani, Yasmin M. Alzayer, Dean Morton, John A. Levon, Nadim Z. Baba
Ectodermal dysplasia is a rare, hereditary, congenital disease that affects the normal development of certain tissues and structures of ectodermal origin. The disease is manifested to different degrees of severity and may involve the nose, eyes, hair, nails, sweat glands, and enamel. This report describes a 14-year-old boy with ectodermal dysplasia, rehabilitated with monolithic, multichromatic maxillary and mandibular computer-aided design and computer-aided manufacturing (CAD-CAM) acrylic resin complete overdentures.
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Analysis of the golden proportion and width/height ratios of maxillary anterior teeth in Arab and Kurdish populations
Source:The Journal of Prosthetic Dentistry
Author(s): Neda Al-Kaisy, Balkees Taha Garib
Statement of problemDentists providing anterior restorations are guided by the principles of anatomic tooth dimension. Dental biometrics should consider ethnicity to produce a more comprehensive evaluation.PurposeThe purpose of this clinical study was to analyze the anatomic crowns of maxillary central incisors (CI), lateral incisors (LI), and canines (C) with respect to the golden proportion (GP) and width/height (W/H) ratio in Kurdish and Arab populations.Material and methodsMaxillary gypsum casts were obtained from 100 participants (50 from a Kurdish and 50 from an Arab population). Standardized digital photographs of each cast were recorded. The apparent and actual anterior tooth dimensions were determined by ImageJ software for the calculation of the GP and W/H ratio. Data were statistically analyzed using ANOVA to investigate ethnic, sex, and arch side differences. The chi-square test was used to explore the GP, and the 1-sample t test was used to test the ideal W/H ratio (α=.05).ResultsThe GP was found in both the Kurdish and Arab groups in the LI/CI mean (0.62, 0.63), but not in the C/LI mean (0.69, 0.73). No difference due to sex was detected in the LI/CI in either ethnic group, but Kurdish men had significantly larger C/LI than women (0.73, 0.66, P=.006) and larger right-side LI/CI than left (0.63, 0.60, P=.049). The W/H ratio was higher than the predicted ideal ratio of 80% (range, 88% to 90%). The LI W/H ratio in Arabs was significantly larger than in Kurds (90.3% versus 82.7%, respectively; P<.001).ConclusionsThe GP was found to exist between the apparent widths of maxillary anterior teeth LI/CI for the both populations in both men and women but not for C/LI. No ideal ratio was detected for the W/H ratios. Specific population characteristics must be taken into consideration, especially when applying the proportions to Kurdish individuals.
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Modification of Makzoume vertical dimension recorder for individuals with a beard
Source:The Journal of Prosthetic Dentistry
Author(s): Jitendra J. Mete, Ulhas E. Tandale, Vilas L. Rajguru, Sonali S. Dahiwale
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Effect of coloring and sintering on the translucency and biaxial strength of monolithic zirconia
Source:The Journal of Prosthetic Dentistry
Author(s): Nazmiye Sen, Ibrahim Bülent Sermet, Sevki Cinar
Statement of problemThe influences of coloring and sintering procedures on the optical and mechanical properties of monolithic zirconia have not been thoroughly investigated.PurposeThe purpose of this in vitro study was to investigate the effects of the coloring procedure and of varying final sintering temperatures on the translucency parameter (TP) and biaxial flexural strength (BFS) of monolithic zirconia.Material and methodsDisk-shaped specimens (N=210) of 2 different monolithic zirconia brands (Vita YZ HTWhite [VYZa]; Vita YZ HTColor A2 [VYZb]; Prettau Zirkonzahn [PZ]; Prettau Anterior Zirkonzahn [PZA]) with a diameter of 15 mm and a thickness of 1.0 ±0.05 mm were prepared. Half of the specimens prepared from noncolored blocks (VYZa, PZ, and PZA) received coloring liquid application. Then, the specimens were divided into 3 subgroups (n=10) according to the final sintering temperatures (1350°C, 1450°C, and 1600°C). The TP was determined by using a reflection spectrophotometer, and the BFS was tested with the piston-on-3-ball method in a universal testing machine. Data were statistically analyzed by multivariate multiple regression and Bonferroni tests (α=.05).ResultsSignificant differences were obtained among the groups based on the results of the TP and BFS (P<.05). The TP was affected by the changes in final sintering temperature. The varying final sintering temperatures demonstrated no significant effect on the BFS, except in group PZ (noncolored) that produced lower BFS when sintered at 1350°C than the subgroups sintered at 1450°C and 1600°C (P<.05). Coloring liquid application significantly decreased the TP of VYZa (sintered at 1350°C) but produced no significant effect on the groups PZ and PZA. Additionally, the coloring procedure had no significant effect on the BFS of tested materials (VYZa, PZ, and PZA) (P>.05).ConclusionsIncreased sintering temperature leads to increased translucency with minimal impact on the BFS. The coloring procedure should be considered at the time of material selection to avoid possible reduction in translucency.
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Aluminum barrier laminate or plastic tube as a dispenser for modeling plastic impression compound for border molding
Source:The Journal of Prosthetic Dentistry
Author(s): Jitendra J. Mete, Vilas L. Rajguru, Shankar P. Dange
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Marginal discrepancy of noble metal–ceramic fixed dental prosthesis frameworks fabricated by conventional and digital technologies
Source:The Journal of Prosthetic Dentistry
Author(s): Ahmed Afify, Stephan Haney, Ronald Verrett, Michael Mansueto, James Cray, Russell Johnson
Statement of problemStudies evaluating the marginal adaptation of available computer-aided design and computer-aided manufacturing (CAD-CAM) noble alloys for metal–ceramic prostheses are lacking.PurposeThe purpose of this in vitro study was to evaluate the vertical marginal adaptation of cast, milled, and direct metal laser sintered (DMLS) noble metal–ceramic 3-unit fixed partial denture (FDP) frameworks before and after fit adjustments.Material and methodsTwo typodont teeth were prepared for metal–ceramic FDP abutments. An acrylic resin pattern of the prepared teeth was fabricated and cast in nickel-chromium (Ni-Cr) alloy. Each specimen group (cast, milled, DMLS) was composed of 12 casts made from 12 impressions (n=12). A single design for the FDP substructure was created on a laboratory scanner and used for designing the specimens in the 3 groups. Each specimen was fitted to its corresponding cast by using up to 5 adjustment cycles, and marginal discrepancies were measured on the master Ni-Cr model before and after laboratory fit adjustments.ResultsThe milled and DMLS groups had smaller marginal discrepancy measurements than those of the cast group (P<.001). Significant differences were found in the number of adjustments among the groups, with the milled group requiring the minimum number of adjustments, followed by the DMLS and cast groups (F=30.643, P<.001).ConclusionsMetal–ceramic noble alloy frameworks fabricated by using a CAD-CAM workflow had significantly smaller marginal discrepancies compared with those with a traditional cast workflow, with the milled group demonstrating the best marginal fit among the 3 test groups. Manual refining significantly enhanced the marginal fit of all groups. All 3 groups demonstrated marginal discrepancies within the range of clinical acceptability.
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Stress generation in mandibular anterior teeth restored with different types of post-and-core at various levels of ferrule
Source:The Journal of Prosthetic Dentistry
Author(s): Anatolii Savychuk, Marianthi Manda, Christos Galanis, Christofer Provatidis, Petros Koidis
Statement of problemPertinent evidence regarding the mechanical integrity of mandibular anterior teeth restored with a post-and-core is limited.PurposeThe purpose of this finite element analysis study was to compare the impact of the post type (glass fiber post-and-resin core or cast post-and-core) along with the ferrule effect on the stress fields generated in endodontically treated mandibular lateral incisors and canines.Material and methodsThree-dimensional models of the segmented mandible were developed. Mandibular incisors and canines with or without a 2-mm circular ferrule and restored with a cast post-and-core or glass fiber post-and-resin core were simulated and subjected to linear elastic static analysis. The principal stress values were calculated. von Mises equivalent stresses were used to evaluate the stress.ResultsMaximum principal stresses in dentin were highest in incisors, with a ferrule. Stress parameters in composite resin core in both incisors and canines were critically close to the tensile failure limit of the core material. Cast post-and-cores cemented in incisors without a ferrule accumulated the highest stresses, exceeding the tensile failure limit of resin-modified glass ionomer cement.ConclusionsTooth preparation with a ferrule led to a remarkable rise in stress in the dentin of mandibular incisors but favored the mechanical integrity of the restoration.
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A 3D-printed guide for lateral approach sinus grafting: A dental technique
Source:The Journal of Prosthetic Dentistry
Author(s): Brian J. Goodacre, Rajesh S. Swamidass, Jaime Lozada, Aladdin Al-Ardah, Erik Sahl
Lateral approach sinus grafting has become a routine and predictable surgical method of augmenting the pneumatized sinus for implant placement. Outlining the lateral window access can be a challenging task for the clinician to envision and execute. Improper extension and access to the maxillary sinus can prevent proper placement of graft materials and lead to complications. The purpose of this report was to demonstrate a technique that will allow the precise planning of the lateral approach using radiographic information and 3-dimensional (3D) software to 3D-print a surgical guide.
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Diagnostic accuracy of 4 intraoral radiographic techniques for misfit detection at the implant abutment joint
Source:The Journal of Prosthetic Dentistry
Author(s): Pollyana Darós, Vinícius Cavalcanti Carneiro, Amanda Pasolini Siqueira, Sergio Lins de-Azevedo-Vaz
Statement of problemA misfit or gap at the implant–abutment joint (IAJ) requires detection as it may compromise the health of the peri-implant tissue. However, which radiographic technique provides the most orthogonal relationship between the central beam and the implant/image receptor is unclear.PurposeThe purpose of this in vitro study was to evaluate the diagnostic accuracy of 4 intraoral radiographic techniques on misfit detection at the IAJ.Material and methodsTwenty implants were placed in polyamide jaws, and customized dental implant abutments with a metal collar were installed. Different gaps were simulated by placing one or three 50-μm-thick polyester strips at the IAJ; the absence of the strip represented the control group (no gap). The 4 radiographic techniques were evaluated by using different film holders: a periapical with bisecting angle (PBA), a bitewing interproximal (BI), a periapical with standard paralleling (PSP), and a periapical with modified paralleling (PMP) holder (with a custom-made paralleling index). A total of 240 digital radiographs were evaluated by 4 clinicians experienced with dental implants. Differences were evaluated by using receiver operating characteristic (ROC) curves (Az) and Fisher tests (α=.05). Diagnostic values (sensitivity, specificity, accuracy, and positive and negative predictive values) were also obtained. The Kappa test was used to assess intra- and interevaluator reproducibility, which ranged from moderate to almost perfect.ResultsAll diagnostic values, except specificity, were lower for the PBA technique for both the 50- and 150-μm gaps. Az values for the PBA technique were significantly lower than those obtained for the other 3 techniques (P<.05), which did not differ from each other. The 150-μm gaps were more easily detected than the 50-μm gaps only for PBA (P<.05).ConclusionsThe BI, PSP, and PMP techniques detected misfits at the IAJ most accurately. The PBA technique is not recommended for this purpose.
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Degree of conversion of resin cement with varying methacrylate compositions used to cement fiber dowels: A Raman spectroscopy study
Source:The Journal of Prosthetic Dentistry
Author(s): Abdulelah M. BinMahfooz, Osama A. Qutub, Thamer Y. Marghalani, Mohammed F. Ayad, Abdulhamaid A. Maghrabi
Statement of problemStudies on the degree of conversion of dental cement in relation to the number of methacrylate components are lacking.PurposeThe purpose of this in vitro study was to evaluate the degree of conversion of single- and multicomponent methacrylate-containing dental cements around opaque and translucent fiber dowels at varying depths.Material and methodsTeeth were prepared for standard endodontic therapy, and a dowel space was created. Opaque and translucent fiber dowels consisting of Aestheti-Plus (AP) and FiberKleer were cemented with 4 methacrylate (MA)-containing cements, including RelyX U100 (R), which contains TEGDMA; Duolink (D), which contains TEGDMA and BisGMA; and Variolink N LC (V) and Breeze (B), which contain TEGDMA, BisGMA, and UDMA. Light-emitting diode polymerization was performed for 60 seconds. The specimens were immediately cut into halves and measured within the first hour at depths of 1, 3, and 5 mm using Raman spectroscopy, and the degree of conversion (DC) of resin cement was calculated. Data were analyzed using 3-way ANOVA and the Tukey multiple comparison test (α=.05).ResultsThe measured dowel regions were not significantly different at various depths (P=.10). The dowel and cement types significantly influenced the degree of conversion of the cement (P<.05). The V and B cements exhibited a higher DC than D and R cements. With AP dowels, the DC of cement D was lower than that of the V, B, and R cements.ConclusionsWithin the limitations of this in vitro study, the degrees of conversion of the tested resin cements were not affected by the tested dowel depths. Higher DC was found in cement with more than 2 types of flexible MA. Opaque dowels produced a lower DC than translucent dowels.
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Esthetic abutment design for angulated screw channels: A technical report
Source:The Journal of Prosthetic Dentistry
Author(s): Satoshi Sakamoto, Munehiko Ro, Aladdin Al Ardah, Charles Goodacre
Angulated screw channel system abutments (ASCs) have recently been introduced to address the problem with visible screw access that may compromise esthetics. ASCs allow the screw access to be modified up to 25 degrees relative to the implant axis. However, a widened channel, which may cause thinning of the facial ceramic, is needed at the implant screw head to allow for proper engagement of the screwdriver. This technical report introduces a custom titanium insert design, the Satoshi Sakamoto (SS) abutment. The SS abutment consists of a custom titanium metal insert and zirconia coping in which the access hole is located in an esthetic position with an ASC system. The SS abutment results in a crown with more normal crown dimensions that also provides more space for the soft tissues. This SS abutment design allows clinicians to obtain screw-retained restorations with optimal esthetics and mechanical strength.
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Asymmetric bone remodeling in mandibular and maxillary tori
Abstract
Objectives
Tori are frequent paucisymptomatic bony outgrowths of the oral cavity in three locations: torus palatinus (TP), mandibularis (TM), and maxillaris (TMax). Their usually described histological characteristics are unspecific: normal cortical bone with more or less trabecular bone. The aim of this study was to describe tori's specific morphological and histomorphometric characteristics.
Materials and methods
Histological characteristics in a series of 18 tori collected after surgical removal were analyzed. Microcomputed tomography provided a 3D analysis. Mineral apposition rate (MAR) was measured after double tetracycline labeling. Osteoid tissue was identified by Goldner's trichrome and osteoclasts by the tartrate resistant acid phosphatase identification in undecalcified sections. Iron and aluminum were detected by histochemical staining methods. Osteoid thickness and MAR were determined at the outer surface of the torus and in the Haversian canals.
Results
Tori appeared made of lamellar Haversian bone in 16/18 cases. Osteoid thickness did not differ between the outer surface and within the canals. An asymmetric bone remodeling was observed in the Haversian canals of 15 tori: osteoid seams were deposited on the side close to the free torus surface, and Howship's lacunae with numerous osteoclasts were observed on the opposite side. A high MAR was found at the surface of the tori and within the canals. There was no iron or aluminum deposit.
Conclusions
Tori may be characterized by a specific asymmetric bone remodeling which seems to determine their shape.
Clinical relevance
This finding could constitute a specific histological feature allowing to differentiate tori from exostoses.
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The elevated activation of NFκB and AP-1 is correlated with differential regulation of Bcl-2 and associated with oral squamous cell carcinoma progression and resistance
Abstract
Objectives
Oral cancer is the sixth most common cancer in the world. Failure of chemoradiation therapy is a major concern for treating oral cancer patients. The objective of this study is to determine the B cell lymphoma-2 (bcl-2) expression and its regulation by nuclear factor κB (NFκB) and activator protein 1 (AP-1) in oral cancer progression and chemoradiation resistance.
Materials and methods
In the present study, a total of 123 (n = 123) human samples were included. Briefly, 64 fresh samples were from adjacent normal (AN), primary oral tumors without treatment (PT), and tumors with resistance to chemoradiation therapy with local recurrence (RCRT). Fifty-nine samples were human tongue cancers and normal samples (TMA). Messenger RNA (mRNA) expression levels of bcl-2 and protein levels of bcl-2, NFκB, AP-1, and inactive GSK3α/β were measured by semiquantitative RT-PCR, immunohistochemistry, Western blot, and ChIP analysis.
Results
Increased bcl-2 expression was observed in PT compared to AN. The RCRT tumors showed maximum expression of bcl-2 mRNA and protein over the PT and AN groups. Bcl-2 protein and mRNA expression were positively correlated with NFκB and AP-1 expression. AP-1 expression was strongly correlated with bcl-2 in the RCRT group of tumors. Further, inactive GSK3α/β showed a positive trend with bcl-2 expression in oral tongue cancer specimens.
Conclusion
Collectively, our results demonstrated cumulative effect of AP-1 and NFĸB for bcl-2 gene regulation in overall PT progression and chemoradiation resistance. The study provides evidence of increased bcl-2 mRNA/protein fueled by NFĸB in PT and AP-1 in RCRT. These regulations of bcl-2 by NFκB and AP-1 are important in OSCC progression and chemoradiation resistance.
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Four-year outcomes of restored posterior tooth surfaces—a massive data analysis
Abstract
Objectives
There is only sparse knowledge concerning the outcomes of treatments with posterior permanent restorations in general practice settings. This study aimed at evaluating outcomes based on a large dataset by using a novel approach on a tooth surface basis.
Materials and methods
The study based on routine data from a major German national health insurance company. Respective treatment fee codes allowed for tracking the clinical courses on a tooth surface level. The study intervention was defined as the placement of a restoration on an interproximal or occlusal posterior tooth surface regardless of its actual extension and material on which no information was available. All surfaces restored between January 1st, 2010 and December 31st, 2013 were included. Kaplan-Meier survival analyses were conducted to estimate four-year survival. The primary outcome was a restorative re-intervention on the same tooth surface. Separate analyses were performed for the secondary outcomes "crowning" and "extraction".
Results
Over ten million interproximal surfaces and eight million occlusal surfaces in nine million posterior teeth had been restored. At 4 years, the cumulative survival rates concerning the primary outcome "re-intervention" for mesial surfaces (81.4%; CI 81.3–81.5%) and distal surfaces (81.2%; CI 81.1–81.2%) differed significantly from those for occlusal surfaces (77.0%; CI 76.9–77.0%). Restored surfaces in premolars showed significantly higher survival rates compared to molars. Four-year survival rates for the secondary outcome "crowning" were 91.9% (CI 91.8—91.9%) for mesial surfaces, 92.1% (CI 92.1–92.2%) for distal surfaces and 93.3% (CI 93.2–93.3%) for occlusal surfaces. The respective rates for the secondary outcome "extraction" were 94.5% (CI 94.5–94.5%) for mesial surfaces, 94.8% (CI 94.7–94.8%) for distal surfaces and 95.4% (CI 95.4–95.5%) for occlusal surfaces.
Conclusions
Re-interventions after restorative treatment play a significant role in general practice settings. Surface-related survival rates of restorations reveal a need for improvement.
Clinical relevance
This study allows the estimation of the probability of re-interventions after restoring posterior tooth surfaces. It is based on several million cases from general practises under the terms and conditions of a national health insurance system.
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Choto Family Dentistry coming
Darrel Clabough, D.D.S., left, and Tommy Spears, D.D.S., both of Maryville, are partnering to open Choto Family Dentistry in Markets at Choto. They said they hope to be open in March.
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Halitosis: effect of periodontal treatment
Eight low quality studies were included in this review of the effect of scaling and root planing, professional tooth cleaning together with oral hygiene instructions on halitosis. All the studies demonstrated a positive effect but the findings need to be interpret cautiously.
The post Halitosis: effect of periodontal treatment appeared first on National Elf Service.
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How does sinus surgery affect topical irrigation distribution?.
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Potential Effect of Leukocyte-Platelet-Rich Fibrin in Bone Healing of Skull Base: A Pilot Study
Background. Reconstruction of surgical defects following cranial base surgery is challenging. Others have demonstrated that leukocyte-platelet-rich fibrin (L-PRF) stimulates tissue healing and bone regeneration. However, these studies have addressed mostly maxillofacial surgical wounds. Objective. The objective of this study was to assess the possible adjuvant role of L-PRF in inducing neoossification of the surgical bone defect in anterior skull base surgery. Methods. We identified patients who had undergone an endoscopic endonasal surgery of the anterior skull base in which L-PRF membranes were used for the reconstruction of the bone defect and who were followed up with postoperative CT scans. CT findings were then correlated with baseline scans and with the CT scans of a patient who had undergone imaging and histologic analysis after maxillofacial surgery in which L-PRF was used and in which we demonstrated bone formation. Results. Five patients fulfilled the inclusion criteria. In four patients, the CT scan demonstrated closure of the bony defect by neoosteogenesis; however, the bone appeared less dense than the surrounding normal bone. A comparison with the control patient yielded similar radiological features. Conclusion. This case series suggests that L-PRF may induce bone healing and regeneration at the surgical site defect. Multi-institutional studies with a larger series of patients are required to confirm this possibility.
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Cancer-related hypercalcemia in oral cancer
Cancer-related hypercalcemia (CRH) is a critical paraneoplastic disorder in advanced cancer patients. In clinical practice, patients with CRH have a poor prognosis. The medical records of 3198 oral cancer patients with CRH diagnosed at Taichung Veterans General Hospital from 1 January 2003 to 31 December 2015 were reviewed. The criteria for patient enrolment were a diagnosis of hypercalcemia or the use of antihypercalcemia medication. Patients who met any of the following criteria were excluded: use of total parenteral nutrition, incomplete serum calcium data, and unknown date of death. (Source: International Journal of Oral and Maxillofacial Surgery)
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Buccal Mucosal Epithelial Cells Downregulate CTGF Expression in Buccal Submucosal Fibrosis Fibroblasts
Abstract
Introduction
Oral submucosal fibrosis (OSMF) is a chronic debilitating fibrotic disease of the oral cavity and is a serious health hazard in south Asia and, increasingly, the rest of the world. The molecular basis behind various treatment modalities to treat OSMF still remains unclear. In this study, we have investigated the in vitro ability of the buccal mucosal cells to reduce the proliferation of the fibroblasts of the fibrotic area in co-culture of cells and also at the molecular levels to reduce the level of connective tissue growth factor (CTGF) in the OSMF fibroblasts (SMF-F).
Materials and Methods
The study compares isolation, morphological and proliferation kinetics of SMF-F and BMF cells with and without co-culturing with BMEs. In addition, we have compared the mRNA expression levels of CTGF in SMF-F co-cultured BME and non-co-cultured SMF-F cells using validated real-time quantitative PCR (RT-qPCR) method.
Results
The basic morphological characteristics of SMF-F were similar to BMF, but the former cells had higher proliferation rate in early passages compared to late passage state. We also observed that the CTGF expression levels in SMF-F under co-culture conditions of BME were consistently and significantly downregulated in all four different SMF-F-derived cells from four different patients.
Conclusion
Rapid proliferation and collagen synthesis in SMF-F as against BMF cells are the factors that confirm the innate nature of fibrosis fibroblasts (SMF-F). Further, the CTGF expression level in SMF-F was significantly suppressed by BME in co-culture conditions against controls (BMF). Considered together, this suggests that the cell therapeutic candidate of BME could be used in treating OSMF.
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Piezoelectric versus conventional implant site preparation: A systematic review and meta-analysis
Abstract
Background
The use of a piezoelectric device (PED) for implant site preparation (ISP) has been introduced to overcome the limitations of using conventional drills (CDs). With little and inconsistent information in the literature regarding their efficiency for preparing implant osteotomies, the objective of this systematic review was to compare the use of CDs to PEDs for ISP with regard to implant stability values, marginal bone level changes, operating time, and dental implant failure rate.
Methods
The systematic review was prepared according to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The literature was searched for studies that assessed the use of CDs and PEDs for ISP. The Cochrane Collaboration risk of bias tool was used to evaluate the selected studies and meta-analyses were performed using statistical software.
Results
A total of 755 citations were identified. Of these, 4 studies with 178 implant osteotomies in 80 participants were included. The pooled estimates for the implant stability showed significant differences between the 2 surgical techniques in favor of PEDs at baseline, 8 and 12 weeks. A statistically significant difference in the operating time was also shown between the 2 techniques with more time required using PED. The differences in marginal bone level changes or implant failure rate were not statistically significant.
Conclusions
With the limitations of this review in mind, PEDs appear to be a viable alternative to traditional drilling techniques for ISP. With the exception of prolonged operating time associated with the use of PEDs, both techniques were comparable in terms of the marginal bone level changes and the risk of implant failure. The favorable influence of the implant stability pattern related to the use of PEDs on the predictability of immediate and early loading protocols need to be confirmed in future studies.
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Assessment of interleukin-1β, interleukin-6, and tumor necrosis factor-Α levels in the peri-implant sulcular fluid among waterpipe (narghile) smokers and never-smokers with peri-implantitis
Abstract
Background
It is hypothesized that levels of interleukin (IL)-1β, IL-6 and tumor necrosis factor (TNF)-α are significantly higher in the peri-implant sulcular fluid (PISF) of waterpipe-smokers (WS) compared with never-smokers with peri-implantitis.
Purpose
The aim of the present convenience sample case-control study was to compare the levels of IL-6, IL-1β, and TNF-α in the PISF of WS and never-smokers with peri-implantitis.
Materials and methods
Demographic data was collected using a questionnaire. Peri-implant probing depth (PPD) was measured and crestal bone loss (CBL) was measured on digital bitewing radiographs. PISF samples were collected using paper strips and the collected PISF volume was determined. levels of IL-6, IL-1β, and TNF-α were measured using enzyme linked immunosorbent assay. Study sample-size was estimated and statistical analysis was performed. P values less than .05 were considered statistically significant.
Results
Sixty-six individuals (33 individuals in group-1 and 33 in group-2) were included. In groups 1 and 2, 41 and 44 implants, respectively were placed. The mean total PPD (P < .001) and peri-implant CBL (P < .001) was statistically significantly higher around implants affected by peri-implantitis in group-1 compared with group-2. The PISF volume (P < .05) collected and levels of IL-1β (P < .01), IL-6 (P < .01), and TNF-α (P < .01) were statistically significantly higher among individuals in group-1 compared with group-2.
Conclusion
WS with peri-implantitis present increased expression of local proinflammatory cytokines in the PISF than never-smokers.
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Peri-implant parameters and C-reactive protein levels among patients with different obesity levels
Abstract
Background
It is hypothesized that peri-implant conditions are worse with increasing severity of obesity, because systemic low-grade inflammatory marker (C-reactive protein [CRP]) is higher in severe form of obese individuals.
Purpose
The aim of the cross-sectional retrospective study was to compare clinical and radiographic peri-implant inflammatory parameters in patients with different levels of obesity and correlate these parameters with CRP levels.
Materials and methods
Eighty-four patients who participated in this study were divided into 4 groups: class I obese (group 1), class II obese (group 2), class III obese (group 3), and nonobese individuals (group 4) were included. Clinical (plaque index [PI], bleeding on probing [BOP], probing depth [PD]) and radiographic (marginal bone loss [MBL]) peri-implant parameters were recorded. Serum CRP were quantified using enzyme-linked immunosorbent assay (ELISA). Clinical peri-implant parameters and serum CRP concentrations were analyzed using 1-way analysis of variance. The Pearson correlation coefficient was used to analyze correlations of CRP levels with any of the clinical and radiographic parameters assessed.
Results
Peri-implant PI, BOP, PD, and MBL were significantly higher in group-1, -2, and -3 patients as compared to nonobese individuals (P < .05). Peri-implant PI, BOP, PD, and MBL were significantly higher in obese patients of group-2 and group-3 as compared to obese patients in group-1 (P < .01). Mean PI, BOP, PD, and MBL were comparable between group-2 and group-3 patients (P > .05). A significant positive correlations were found between CRP levels and BOP (P = .0148) and PD (P = .0425); and significant negative correlation was found for MBL in group 3, respectively (P = .0212).
Conclusion
Clinical and radiographic peri-implant inflammatory parameters and serum CRP were significantly high in patients with severe form of obesity. Serum CRP levels correlated with peri-implant bleeding in obese patients. These findings are preliminary and long-term controlled trials are recommended to support these outcomes.
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LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity
LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity
LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity, Published online: 16 November 2017; doi:10.1038/bjc.2017.412
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Cumulative incidence rates for CNS and non-CNS progression in two phase II studies of alectinib in ALK-positive NSCLC
Cumulative incidence rates for CNS and non-CNS progression in two phase II studies of alectinib in ALK-positive NSCLC
Cumulative incidence rates for CNS and non-CNS progression in two phase II studies of alectinib in <i>ALK</i>-positive NSCLC, Published online: 16 November 2017; doi:10.1038/bjc.2017.395
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Reply to ‘Comment on ‘Efficacy of stereotactic body radiotherapy in oligorecurrent and in oligoprogressive prostate cancer: new evidence from a multicentric study’’
Reply to 'Comment on 'Efficacy of stereotactic body radiotherapy in oligorecurrent and in oligoprogressive prostate cancer: new evidence from a multicentric study''
Reply to 'Comment on 'Efficacy of stereotactic body radiotherapy in oligorecurrent and in oligoprogressive prostate cancer: new evidence from a multicentric study'', Published online: 16 November 2017; doi:10.1038/bjc.2017.406
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Comment on ‘Efficacy of stereotactic body radiotherapy in oligorecurrent and in oligoprogressive prostate cancer: new evidence from a multicentric study’
Comment on 'Efficacy of stereotactic body radiotherapy in oligorecurrent and in oligoprogressive prostate cancer: new evidence from a multicentric study'
Comment on 'Efficacy of stereotactic body radiotherapy in oligorecurrent and in oligoprogressive prostate cancer: new evidence from a multicentric study', Published online: 16 November 2017; doi:10.1038/bjc.2017.342
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Treponema denticola chymotrypsin-like proteinase may contribute to orodigestive carcinogenesis through immunomodulation
Treponema denticola chymotrypsin-like proteinase may contribute to orodigestive carcinogenesis through immunomodulation
<i>Treponema denticola</i> chymotrypsin-like proteinase may contribute to orodigestive carcinogenesis through immunomodulation, Published online: 16 November 2017; doi:10.1038/bjc.2017.409
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NPDS Seeking Patients needing Root Canal Treatment
The Endodontics Department at the Naval Postgraduate Dental School, Bethesda, MD, is currently accepting new patients in need of root canal treatment by our residents. If your dentist has told you that you need a root canal or you are having tooth pain and you have been putting off having a root canal, contact us for a consultation.
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Editorial board
Publication date: December 2017
Source:Calphad, Volume 59
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Alveolar Osteitis and Third Molar Pathologies
We read with great interest the article published in your valuable journal, "Does Administration of Oral Versus Intravenous Antibiotics for Third Molar Removal Have an Effect on the Incidence of Alveolar Osteitis or Postoperative Surgical Site Infections?" by Reiland et al.1 Antibiotics administration in third molar (3M) surgery is an endearing concept in oral surgery and we commend the authors for their excellent literature review and study population. However, we would like to raise some important points.
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Alveolar Osteitis and Third Molar Pathologies
We read with great interest the article published in your valuable journal, "Does Administration of Oral Versus Intravenous Antibiotics for Third Molar Removal Have an Effect on the Incidence of Alveolar Osteitis or Postoperative Surgical Site Infections?" by Reiland et al.1 Antibiotics administration in third molar (3M) surgery is an endearing concept in oral surgery and we commend the authors for their excellent literature review and study population. However, we would like to raise some important points.
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Surgical Treatment of Fibroosseous Lesion in Young Patient with Reduced Mouth Opening
Cranial Maxillofac Trauma Reconstruction
DOI: 10.1055/s-0037-1608697
Fibrous dysplasia is a benign fibroosseous disorder that can affect the maxillary bones, causing aesthetic deformity and functional impairment. This article reports the case of a 13-year-old male patient at the time of diagnosis. The patient showed increased facial volume with relevant asymmetry, having reported the onset of the condition 12 months before. Upon examination, the patient presented an 8-mm mouth opening and an acute inflammatory process associated with tooth 37 pericoronal hood. Upon imaging exam, exuberant bone growth in the left mandibular ramus area of ground glass aspect was observed. After incisional biopsy, fibrous dysplasia was diagnosed and sequentially treated with osteoplasty and coronoid process removal. The patient evolved to a 43-mm mouth opening and favorable aesthetics without recurrence in a 3-year follow-up period. In this case, coronoidectomy and bone plasty proved to be effective, returning aesthetics and function. The patient is supposed to be followed up in the long term.
[...]
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Article in Thieme eJournals:
Table of contents | Abstract | Full text
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Pathology and management of mass in accessory parotid gland region: 24-year experience at a single institution
Masses in the accessory parotid gland (APG) region are clinically rare and their management can lead to conflicts between the need for tumor resection and facial cosmesis. The aim of this study was to analyze the pathological classifications and management of APG lesions in our hospital.
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Anticoagulants are dental friendly
The Clinicians Report newsletter is an invaluable resource for cutting-edge clinical and scientific information for practicing dentists throughout the United States and the world. While we appreciate that the important issue of dental surgery in anticoagulated patients was the topic of "Anticoagulants: are they dental friendly or not?" in the September 2017 issue,1 this article overstates the bleeding risk in anticoagulated dental patients and understates the embolic risks with interruption of anticoagulation for dental procedures, and we respectfully take issue with it for the reasons below.
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Letter to the editor: Comments in relation to the CPC case entitled: “Submucosal nodule in buccal mucosa” Oral Surg Oral Med Oral Pathol Oral Radiol 2016;122:660-665.1
We read with great interest the clinicopathological conference published by Dairot et. al. entitled "Submucosal nodule in buccal mucosa". We reviewed the virtual slides. Histologically, the tumor shows a cribriform pattern with capsular invasion and extra-capsular invasion, the latter is evident in the virtual slides, but not in the published pictures. Basal Cell Adenoma (BCA) of the minor salivary glands is a rare, and we were able to find a single article2 describing capsular invasion. Wilson and Robinson (2014)3 have reported that morphologic observation of local tissue invasion is the best parameter for differentiation BCA from Basal Cell Adenocarcinoma.
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A symptomatic swelling of the upper lip
A 67-year-old woman presented to the School of Dentistry of the Federal University of Pelotas, Brazil, complaining about a slightly painful swelling of the upper lip, lasting around 5 years. The pain was not triggered or aggravated by cold or touch. Intraoral examination showed a 1.0-cm well-defined, sessile, slightly mobile, fibrous submucosal nodule on the right upper lip. The color of the lesion was similar to the adjacent normal mucosa (Figure 1). No other contributing information was collected from the anamnesis.
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Fruit and vegetable intake and cognitive impairment: a systematic review and meta-analysis of observational studies
Fruit and vegetable intake and cognitive impairment: a systematic review and meta-analysis of observational studies
Fruit and vegetable intake and cognitive impairment: a systematic review and meta-analysis of observational studies, Published online: 17 November 2017; doi:10.1038/s41430-017-0005-x
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Comparison of three different adenoidectomy techniques in children - has the conventional technique been surpassed?
Pharyngeal tonsil hyperplasia is the most frequent cause of nasal obstruction and chronic mouth breathing during childhood. Adenoidectomy is the procedure of choice for the resolution of these symptoms. It is not yet known, however, whether the conventional technique ("blind curettage") has been surpassed by more modern adenoidectomy techniques (video-assisted, with the aid of instruments). This study aimed to compare the conventional adenoidectomy technique with two other emerging techniques, performed in a reference otorhinolaryngology center.
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Germinal mosaicism of PAX3 mutation caused Waardenburg syndrome type I
Waardenburg syndrome mutations are most often recurrent or de novo. The rate of familial recurrence is low and families with several affected children are extremely rare. In this study, we aimed to clarify the underlying hereditary cause of Waardenburg syndrome type I in two siblings in a Chinese family, with a mother affected by prelingual mild hearing loss and a father who was negative for clinical symptoms of Waardenburg syndrome and had a normal hearing threshold.
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Musculo-mucous web velum and velopharyngeal dysfunction associated with 8q22.1–22.2 microduplication
This report presents a rare case of isolated non-cleft velopharyngeal dysfunction (VPD). An eight-year-old child presented 1. aphenotypically unique band-gap pattern of the velar musculature with anteroposterior insertion; 2. a mosaic partial trisomy on chromosome 19 as well as microduplications on chromosomes 8 and 22. Following cytogenetic analysis, microduplication on chromosome 8 was found in another member of her family. A family history of VPI with hypernasality and nasal regurgitation was reported over three different generations on the patient's maternal side.
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Diagnosis of Mesiodistal Vertical Root Fractures in Teeth with Metal Posts: Influence of Applying Filters in Cone-beam Computed Tomography Images at Different Resolutions
The aim of this article was to evaluate the influence of applying filters in cone-beam computed tomography (CBCT) images at different resolutions. These CBCT images were obtained for diagnosing mesiodistal vertical root fractures (VRFs) in teeth with metal posts.
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Influence of Mixed Additives on the Physicochemical Properties of a 5.25% Sodium Hypochlorite Solution: An Unsupervised Multivariate Statistical Approach
This article reports for the first time the effects of multiple additives (polyethylene glycol 400, Triton X-100, benzalkonium chloride, and ethyl formate) on the surface tension, pH, and viscosity of 5.25% sodium hypochlorite (NaOCl) irrigant solution. Advanced statistical approaches based on unsupervised multivariate analysis (cluster analysis and principal component analysis) were used to quantify the variability of the physicochemical properties of the modified NaOCl solution for the first time in dentistry.
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A judge decided this Brampton dentist is allowed to practise despite...
A court has reinstated the licence of a Brampton dentist and part-time standup comedian who, according to the judge's ruling, admitted to police and a psychiatrist that he masturbated in front of teenage girls in Florida this year. In a decision that has left Ontario's dental regulator "very disappointed," Superior Court Justice Nancy Spies ordered last week that a suspension on the licence be lifted immediately and that the Royal College of Dental Surgeons of Ontario pay Dr. Ron Rohringer $20,000 in court costs.
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Cancer-related hypercalcemia in oral cancer
Cancer-related hypercalcemia (CRH) is a critical paraneoplastic disorder in advanced cancer patients. In clinical practice, patients with CRH have a poor prognosis. The medical records of 3198 oral cancer patients with CRH diagnosed at Taichung Veterans General Hospital from 1 January 2003 to 31 December 2015 were reviewed. The criteria for patient enrolment were a diagnosis of hypercalcemia or the use of antihypercalcemia medication. Patients who met any of the following criteria were excluded: use of total parenteral nutrition, incomplete serum calcium data, and unknown date of death.
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Submental tracheal intubation: A useful alternative during orthognathic surgery in an acromegalic patient with a history of cranial base surgery
Publication date: Available online 15 November 2017
Source:Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
Author(s): Ryosuke Kita, Seiji Kondo, Mika Seto, Masayasu Hirase, Kyoichi Narihira, Ryosuke Mano, Shiho Tanaka, Toshihiro Kikuta
Submental tracheal intubation is an alternative technique for use in patients with airway difficulties in whom oro- or naso-tracheal intubation is contraindicated. Here, a planned submental tracheal intubation was used during orthognathic surgery in an acromegalic patient who had previously undergone trans-sphenoidal surgery (TSS) for removal of a pituitary adenoma, which involves removal of the sellar bone covering the anterior surface of the cavernous sinus. This helped prevent serious complications, such as intracranial penetration during nasotracheal intubation. Submental tracheal intubation can reduce the morbidity associated with repeated attempts at tracheal intubation in acromegalic patients who have undergone cranial base surgery and in whom orthognathic surgery is planned.
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Peripheral facial palsy after set-forward orthognathic surgery: A case report and review of literature
Publication date: Available online 15 November 2017
Source:Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
Author(s): Eiji Mitate, Jun-Nosuke Hayashida, Takeshi Toyoshima, Takeshi Noguchi, Toru Kitahara, Ichiro Takahashi, Tetsuro Ikebe, Seiji Nakamura
The complications of orthognathic surgery may include but are not limited to postoperative unexpected bleeding, abnormal fractures, infections, and nerve damages. Peripheral facial palsy is rare. We report a case of 23-year-old woman with signs of malocclusion, including pectus excavatum, wrist sign, and thumb sign for Marfan syndrome (MFS) underwent peripheral facial palsy after orthognathic surgery with mandibular advancement. Because cardiovascular, thoracic, and ocular abnormalities were absent, she was suspected of having MFS but not definitively diagnosed. On the other hand, she was diagnosed with a maxillary protrusion with mandibular retrognathism. After presurgical orthodontic treatment, we performed Le Fort I osteotomy and 8mm advancement by bilateral sagittal split ramus osteotomy. Because the periosteum is vulnerable, we checked the bleeding more are fully and frequently during the operation than usual. The day after the operation, peripheral facial palsy with inability to wrinkle the forehead, blink, and grimace were found. The patient was administered mecobalamin, linear polarized infrared irradiation, and stellate ganglion blocks. The patient was also administered valacyclovir for 6days and steroid pulse therapy for 7days. Six months after the operation, the facial palsy had disappeared completely.In 58 previous reports, the facial palsy was induced by the reasons, including the operative procedure, postoperative hematoma, edema, perioperative stress, and tissue vulnerability. In the present case, because of the suspected MFS, tissue vulnerability was considered to be one of the major cause of facial palsy, which should be paid attention more carefully in addition to general causes.
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A novel method to prevent biting through nasolabial flap: Modified oral screen
Publication date: Available online 15 November 2017
Source:Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
Author(s): Zainab Chaudhary, Ranjeet Bodh, Pankaj Sharma, Sujata Mohanty, Anjali Verma
ObjectiveOral submucous fibrosis (OSMF) is a chronic, progressive precancerous condition of oral mucosa, predominantly seen in the Indian subcontinent. This technical note describes the use of oral screen prosthesis used as an adjunct to surgery to prevent relapse following surgical correction.MethodsThe modified oral screen appliance was inserted in the patient's labial and buccal vestibule as oral screen. The appliance was intended to be used as an oral stent along with mouth exercises to counteract relapse of the corrected mouth opening.ResultsThe possibility of flap shrinkage and interference with occlusion results in surgical failure of the treatment of OSMF. Securing the flap in position using oral screen prosthesis has been tried as an adjunct to treat such cases.ConclusionsThis modified approach can be performed in routine clinical practice, making the rehabilitation of such a case possible with relative ease.
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A case of chondrosarcoma in the temporomandibular joint
Publication date: Available online 15 November 2017
Source:Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
Author(s): Kenji Fukada, Toshihiro Okamoto, Noriyuki Shibata, Tomohiro Ando
We report a case of a 78-year-old woman with chondrosarcoma in the temporomandibular joint. On examination, swelling of the right preauricular region and pain when opening the mouth was observed. Imaging revealed an irregular-shaped radiopaque mass in the right mandibular condyle with bone resorption. After performing tumorectomy under general anesthesia, histopathological examination revealed that tumor cells had slightly hyperchromatic nuclei that lacked significant pleomorphism, displayed polygonal or stellate profiles of the soma, and formed nodular nests in the homogeneous fibrous cartilage matrix. The pathological diagnosis was chondrosarcoma, Grade II of the right temporomandibular joint.
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Residual cementoblastoma: An unusual presentation of a rare odontogenic tumor
Publication date: Available online 15 November 2017
Source:Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
Author(s): Lucas Ribeiro Teixeira, Jessica Luana dos Santos, Luciana Yamamoto Almeida, Carla Bento Nelem-Colturato, Ricardo Ferreira de Paula, Fernando Radaelli Osório Oliveira, Jorge Esquiche León
Cementoblastoma is a benign ectomesenchymal odontogenic tumor characterized by the formation of cementum mass continuous with the tooth root, preferentially a permanent mandibular first molar. Clinically, the tumor shows a tender, sometimes painful, cortical plate expansion, frequently in male patients under 30 years old. Radiographically, the lesion exhibits a radiopaque mass, surrounding by a thin radiolucent rim, and attached to the tooth root. Microscopically, it is visualized a calcified matrix lined by large hyperchromatic cementoblasts with radiating columns at the periphery. Treatment of choice is surgery. Interestingly, rare cases of residual (after tooth extraction only) and recurrent (after tumor removal plus tooth extraction) cementoblastomas have been reported, which can be misdiagnosed if an appropriate clinicopathological correlation is not considered. Here, we present a rare case of residual cementoblastoma affecting an 18-year-old male patient at level of permanent mandibular first molar. Thus, residual cementoblastoma is an unusual presentation which should be included in the differential diagnosis of cementum-forming and bone-forming tumors affecting the jaws.
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Exposure to a community-wide campaign is associated with physical activity and sedentary behavior among Hispanic adults on the Texas-Mexico border
Despite evidence for the use of community-wide campaigns to promote physical activity, few evaluations of community–wide campaigns in Hispanic communities exist. This study assessed the associations of exposur...
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Impact of a decision aid about stratified ovarian cancer risk-management on women’s knowledge and intentions: a randomised online experimental survey study
Risk stratification using genetic and other types of personal information could improve current best available approaches to ovarian cancer risk reduction, improving identification of women at increased risk o...
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Cosmetic and Reconstructive Surgery of Congenital Ear Deformities
It is my privilege and great pleasure to introduce this issue of Facial Plastic Surgery Clinics of North America with a comprehensive focus on cosmetic and reconstructive surgery of congenital ear deformities. First and foremost, I wish to thank sincerely our many wonderful authors who graciously offered their time, commitment, and world-class expertise in this specialty subject for the benefit of our readership.
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Forthcoming Issues
Controversies in Facial Plastic Surgery
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Cosmetic Otoplasty
Otoplasty for prominent ears is a rewarding yet exacting surgery that demands the precise application of anatomic knowledge, anthropometric norms, and surgical creativity. The practitioner must be able to use a variety of different techniques to provide durable and acceptable cosmetic results to patients. This article provides an in-depth description of normal and abnormal auricular anatomy, the historical context for modern otoplasty, and describes in detail the common otoplastic procedures currently performed.
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Autologous Rib Microtia Construction
Nagata technique becomes most popular method of autologous rib microtia construction. To achieve successful outcome, 3 keys must be perfect: skin envelope, 3D cartilage framework, and proper location of the construct. The first step of the surgery is to identify "auricular rectangle." Relationship between the auricular rectangle and the vestige will determine if the vestige is usable for surgery. Rib cartilage must be harvested without perichondrium to prevent chest deformity. Lobule split technique is the hallmark of the Nagata technique, which allows skin envelope expansion, and allows deeper conchal cavity. Surgeons must master 3D framework construct before clinical cases.
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Contributors
J. REGAN THOMAS, MD, FACS
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Surgical Otoplasty
Otoplasty is one of the first procedures learned during residency. A myriad of surgical techniques and nuances exist. Many have merit, some are ineffective, some destructive, and some frankly fanciful. Adopting an effective and safe technique should be based on proven efficacy and effectiveness to avoid early disappointments. We present a review of traditional otoplasty techniques and more recent innovations. Their pros and cons are discussed in view of the relative risks/benefits balance. Recurrence rates are low for most techniques. Some techniques carry a higher risk of significant complications. A ladder approach preferring techniques that minimize cartilage damage appears advisable.
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Auricular Prostheses in Microtia
The progress made in the development of the silicones and percutaneous titanium implants allow for rehabilitation of patients with microtia with an inconspicuous auricular prosthesis. The art of making the prosthesis by the dedicated anaplastologist is the key for the success of this approach. Most patients with microtia desire camouflage. The greatest advantage of the auricular prosthesis is that it can be manufactured as a mirrored replica of the opposite side. The outcome is predictable. Computer science with virtual planning and rapid prototyping is about to revolutionize the process of prosthetic auricular rehabilitation.
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Cosmetic and Reconstructive Surgery of Congenital Ear Deformities
FACIAL PLASTIC SURGERY CLINICS OF NORTH AMERICA
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Atresiaplasty in Congenital Aural Atresia
Patients with microtia and congenital aural atresia should have a comprehensive hearing assessment early in life. Options for hearing habilitation should be presented, and children with bilateral aural atresia should be fitted with a bone conducting hearing device to support normal speech and language development. If atresia surgery is pursued, the microtia surgeon must be aware of certain principles. This article presents recommendations on options for potentially improving hearing in children with congenital aural atresia: assessing surgical candidacy; chronology and timing of surgeries; functional importance of certain ear structures; and understanding the possible locations of an aberrant facial nerve to avoid injury in these patients.
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Otoplasty for Congenital Auricular Malformations
Among the less common congenital auricular anomalies are cryptotia, Stahl ear, constricted ear, and macrotia. The vast majority of these occur spontaneously without accompanying syndromes or other deformities. This article provides a comprehensive overview of these anomalies, as well as common techniques to correct these anomalies.
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Pediatric Microtia Reconstruction with Autologous Rib
Reconstruction of the microtic ear is one of the most challenging, yet gratifying surgical experiences. Careful planning, attention to detail, and conservative tissue management are necessary for excellent results. Technologies continue to evolve; with the advancement of cartilage tissue engineering, the future of ear reconstruction is very promising.
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Nonsurgical Management of Congenital Auricular Anomalies
Congenital auricular deformities often can be corrected by neonatal ear molding techniques, which have evolved significantly over a 25-year period with commercially available molding systems now available. Indications for molding and methodology for best optimizing results have been well described in the literature, although recent studies have explored methodology for reduction in the cost of technique and also called for increased awareness among pediatric practitioners of the importance of early institution of therapy.
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Lipari Foods, LLC. Issues Voluntary Product Recall of Specific Dark Chocolate Products Due to Undeclared Milk Allergen
Lipari Foods, LLC has issued a voluntary recall of specific dark chocolate products packaged by sister company JLM due to an undeclared milk allergen. People who have an allergy or severe sensitivity to milk run the risk of a serious or life-threatening allergic reaction if they consume these products. The products are safe for consumption by those who do not have an allergy or severe sensitivity to milk.
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Comparison of diagnostic methods for early interproximal caries detection with near-infrared light transillumination: an in vivo study
Abstract
Background
Although numerous studies have used digital intraoral imaging, only a few studies have used photo-optical methods for the diagnosis of caries. Moreover, several limitations exist in terms of observers (experience and specialty) and the caries lesion itself. Hence, the aims of this study were to evaluate the diagnostic capability of near-infrared light transillumination (NILT) and PSP-Bitewing radiographs and to compare the interobserver and intraobserver differences in addition to observers' experience level to detect early interproximal caries lesions in vivo.
Methods
A total of 52 untreated posterior teeth with and without varying degrees of early interproximal carious lesions were included. Bitewing radiographs using digital phosphor plates (PSP-Bitewing) and NILT were used to clarify the diagnosis. An oral and maxillofacial radiologist and a restorative dentistry consultant evaluated the images twice. A separate appointment for clinical validation and restoration was made. Kappa coefficients were calculated to assess both intraobserver and interobserver agreements for each evaluation method. Scores obtained from PSP-Bitewing and NILT were compared with the clinical validation via receiver operating characteristic (ROC) analysis.
Results
No significant differences were found between PSP-Bitewing radiography and NILT for detecting early interproximal carious lesions with high average Az results. Both intraobserver and interobserver agreement values were relatively higher for NILT evaluation. The Az values increased at second evaluations for both caries detection methods.
Conclusions
NILT examination has an appropriate sensitivity and diagnostic accuracy for detecting early interproximal caries lesions and can be considered as a method of choice for detecting caries without the use of ionizing radiation.
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Peak Airflow Measurement in Patients With Glottic Insufficiency After Vocal Fold Augmentation
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Implementing Quality Improvement and Patient Safety in Residency Education
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Association of Enrollment in an Aerodigestive Clinic With Reduced Hospital Stay
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Anesthesia Exposure and Neurotoxicity in Children
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Survival Outcomes for T3N0M0 Squamous Cell Carcinoma of the Glottic Larynx
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Reporting of Effect Size and Confidence Intervals
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Error in Byline
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Laryngoscopic Findings and Response to Gabapentin
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Measuring Institutional Quality in Head and Neck Surgery Using Hospital-Level Data
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Prognosis of 5-Year Survival of Chemoradiotherapy-Treated Patients With Nasopharyngeal Carcinoma
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Nationwide Variation in Rates of Thyroidectomy Among US Medicare Beneficiaries
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Extracapsular Dissection vs Superficial Parotidectomy
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Interferon-γ Treatment of Human Laryngotracheal Stenosis–Derived Fibroblasts
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Minimal Important Difference in Voice Handicap Index–10
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Double Parathyroid Adenomas in Monozygotic Twins
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Krouse Classification for Sinonasal Inverted Papilloma With Recurrence
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JAMA Otolaryngology–Head & Neck Surgery
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Unusual Cause of Recurrent Meningitis
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Analysis of the Growth Pattern of Thyroid Cancer in Young Patients
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Rethinking the Growth Pattern of Thyroid Cancer in Young Patients Based on the Fukushima Database
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Editorial Board
Source:American Journal of Otolaryngology, Volume 38, Issue 6
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Table of Contents
Source:American Journal of Otolaryngology, Volume 38, Issue 6
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Guidelines for Contributing Authors
Source:American Journal of Otolaryngology, Volume 38, Issue 6
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Progress and Opportunities for Strengthening Global Health Security
F. J. Angulo et al.
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Newly Recognized Pediatric Cases of Typhus Group Rickettsiosis, Houston, Texas, USA
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Earlsgate Dental Practice in Folkestone closes
A dentist who suddenly closed his doors to patients was under investigation by dental and health authorities, we can reveal. The Earlsgate Dental Practice in Folkestone closed unexpectedly but it has emerged Dr Miodrag Mitic was issued with a warning by the General Dental Council earlier this year.
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CBD College Launches Inaugural Dental Assistant Program Including...
CBD College, the Los Angeles-based non-profit education institution that has been providing quality education and training to students in the medical field for more than 30 years, has launched its newest offering to students-the Dental Assistant program. Classes are scheduled to commence Tuesday, November 14 under the direction of Dental Assistant program director Nicole Alvarez.
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Analysis of Surface Roughness, Fracture Toughness, and Weibull Characteristics of Different Framework—Veneer Dental Ceramic Assemblies after Grinding, Polishing, and Glazing
Abstract
Purpose
To compare the surface roughness and biaxial flexural strength of dental ceramics obtained after chairside surface modification by mechanical polishing procedures, versus laboratory reglazing.
Materials and Methods
Discs (16 × 1.5 ± 1.6 mm) (N = 90) of various framework-veneering combinations were fabricated: D/FC: lithium disilicate/feldspathic ceramic; Z/AL: zirconium dioxide/aluminous ceramic; N/FC: noble alloy/feldspathic ceramic; N/FF: noble alloy feldspathic with fluorapatite; B/FC: base alloy/feldspathic ceramic; B/FF: base alloy/feldspathic ceramic with fluorapatite. In each group 10 specimens were ground using a diamond bur (46 μm) and five were polished with silicone-reinforced disc polishers (25 μm). Surface roughness (Ra) was measured using contact profilometry. After thermocycling in artificial saliva (6000 cycles, 5 to 55 ± 5°C), biaxial flexural strength was measured using "piston-on-three ball" test. The data (N) were analyzed using one-way ANOVA, Bonferroni, and Tukey's posthoc tests. Weibull distribution values were calculated.
Results
Surface roughness was significantly higher in the ground group only (p < 0.0001). Mean fracture toughness was significantly lower for chipping (RK: 287, HS: 22, ISO: 1099 MPa) than for total fracture (p < 0.05), (RK: 841, HS:64, ISO: 3222 MPa). For chipping, Weibull distribution presented the highest shape value (m) for D/FC (3.82-5.07) and for total fracture for B/FC (3.69-4.6).
Conclusion
Chairside surface polishing restored veneer ceramic roughness and mechanical strength to the level of glazing. Feldspathic ceramic with fluorapatite presented better polishing results than conventional feldspathic ceramic did. Ceramic fused to metal was more resistant than lithium disilicate or zirconium dioxide framework-veneer assemblies. Lithium disilicate framework veneered with feldspathic ceramic presented more durability against chipping. Clinical implications: After chairside occlusal modifications in the surfaces of cemented all-ceramic or fused-to-metal FDPs, mechanical polishing procedures should always be carried out.
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Special issue on advanced manipulation
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Accounting for Time-varying Confounding in the Relation between Obesity and Coronary Heart Disease: Analysis with G-estimation, the Atherosclerosis Risk in Communities (ARIC) study
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A novel strategy to address unmeasured confounding when comparing opioid agonist therapies in pregnancy
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Early Pregnancy Perfluoroalkyl Substance Plasma Concentrations and Birth Outcomes in Project Viva: Confounded by Pregnancy Hemodynamics?
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Associations Between Divorce and Onset of Drug Abuse in a Swedish National Sample
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Exposure Biomarkers Indicate More than Just Exposure
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Long Term Risk of Cardiovascular Death With Use of Clarithromycin and Roxithromycin – a Nationwide Cohort Study
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Αναζήτηση αυτού του ιστολογίου
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Publication date: 1 May 2019 Source: Talanta, Volume 196 Author(s): Ruiqing Long, Te Li, Chaoying Tong, Lihui Wu, Shuyun Shi Abstract...
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Oral Cancer Rapid Test Kit Market Rugged Expansion Foreseen by 2024 MilTech Oral cancer is one of the largest group of cancers ...
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