Analytical ChemistryDOI: 10.1021/acs.analchem.0c01271
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Abstract Objective The aim of this randomized controlled trial was to evaluate the interproximal cleaning efficacy of waist-shaped compared with straight soft interdental brushes in patients undergoing nonsurgical periodontal therapy. Materials and methods Ten patients diagnosed with periodontitis stage II or III were scheduled for nonsurgical periodontal...
Abstract Objectives Investigating the effect of carbonation on the strength and structure of calcium silicate-based cement (Biodentine™) in the presence of bicarbonate ion. Materials and methods Cylindrical samples of Biodentine (N = 120) were prepared and cured in deionised water (DW) or bicarbonate solution (BC) for 1 and 2 days and 1, 2 and 4 weeks. After...
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Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03408
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c05607
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c04160
[ASAP] Synthesis of Stilbenes by Rhodium-Catalyzed Aerobic Alkenylation of Arenes via C–H Activation
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03935
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c04330
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02067
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03635
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02597
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c04909
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c05283
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03805
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02438
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Zusammenfassung Ichthyosen sind hereditäre Verhornungsstörungen, die isoliert/nichtsyndromal oder mit assoziierten Erkrankungen an inneren Organen (syndromal) auftreten und bei Neugeborenen zu lebensbedrohlichen Komplikationen führen können. Die Identifizierung der genetischen Ursachen hat zum Verständnis der molekularen Mechanismen, aber auch zur Reklassifizierung geführt. Auch die pathologischen Veränderungen der Hautbiopsien wurden genauer charakterisiert. Dabei konnten bestimmte...
Zusammenfassung Der Mamillen-Areola-Komplex ist Ausgangspunkt verschiedener morphologisch eigenständiger Tumoren und tumorartiger Veränderungen, die sich von den besonderen Strukturen der Mamille, insbesondere den intramamillären Milchgängen, den Anhangsgebilden und dem intramamillären Stroma ableiten lassen. Im Vordergrund stehen dabei epitheliale Tumoren gutartigen Verhaltens wie das Mamillenadenom und der syringomatöse Tumor der Mamille. Seltener sind benigne mesenchymale Tumoren...
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J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1712462 Objectives Local failure of incompletely resected vestibular schwannoma (VS) following salvage stereotactic radiosurgery (SRS) using standard doses of 12 to 13 Gy is common. We hypothesized that dose-escalated SRS, corrected for biologically effective dose, would have superior local control of high-grade VS progressing after subtotal or near-total resection compared with standard-dose SRS. Design Retrospective cohort study....
J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1712180 Objective Data regarding the surgical advantages and anatomic constraints of a hearing-preserving endoscopic-assisted retrolabyrinthine approach to the IAC are scarce. This study aimed to define the minimum amount of retrosigmoid dural exposure necessary for endoscopic exposure of the IAC and the surgical freedom of motion afforded by this approach. Methods Presigmoid retrolabyrinthine approaches were performed on fresh...
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Abstract Angiotensin-II (Ang-II) receptor plays a role in allergic airway inflammation; however, the underlying mechanism and role of macrophages need better understanding. In the present study, angiotensin-II infusion (1 μg/kg/min) in ovalbumin-induced airway inflammation mice model significantly decreased immune cell infiltration, goblet cell hyperplasia, and eosinophil numbers in lungs. Ang-II infusion increased M1 and decreased M2 macrophage...
Abstract Apigenin, a flavonoid found in many plants, has various biological properties. We aimed to investigate the anti-inflammatory and anti-oxidative activity of apigenin against carbon tetrachloride (CCl4)-induced acute liver injury in mice and hydrogen peroxide (H2O2)-induced oxidative stress in HepG2 cells and possible mechanism. In vivo, apigenin significantly reduced alanine aminotransferase (ALT) and aspartate aminotransferase...
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British Journal of Cancer, Published online: 27 May 2020; doi:10.1038/s41416-020-0895-6Producing the appropriate model and drug for intratumoural ablation
British Journal of Cancer, Published online: 27 May 2020; doi:10.1038/s41416-020-0904-9Evaluation of the activity of a chemo-ablative, thermoresponsive hydrogel in a murine xenograft model of lung cancer
British Journal of Cancer, Published online: 27 May 2020; doi:10.1038/s41416-020-0905-8Regorafenib is effective against neuroblastoma in vitro and in vivo and inhibits the RAS/MAPK, PI3K/Akt/mTOR and Fos/Jun pathways
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Abstract Octopus cells in the ventral cochlear nucleus (VCN) have been difficult to study because of the very features that distinguish them from other VCN neurons. We performed in vivo recordings in cats on well-isolated units, some of which were intracellularly labeled and histologically reconstructed. We found that responses to low-frequency tones with frequencies < 1 kHz reveal higher levels of neural synchrony and entrainment to the stimulus than the auditory nerve. In...
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Mariany Morales, a third-year student at the UW School of Dentistry, has been selected to receive a UW Latino Center for Health Student Fellowship, the center has announced. She is one of 10 University of Washington Health Sciences students to receive the award in the fellowship program’s first year. The post Dental student receives Latino Center for Health fellowship appeared first on UW School of Dentistry.
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Abstract Purpose Adversity in early life can induce metabolic defects in exposure to stress in adulthood. Therefore, the exploration of involving mechanisms can be helpful in the treatment of metabolic disorders. So, the present study was conducted in terms of exploring the effects of interaction between early postnatal stress and young adulthood psychological stress on insulin secretion and pancreatic GLUT-2 levels in male rats. ...
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Laryngeal botulinum toxin injection is an important treatment modality for spasmodic dysphonia and other laryngeal disorders. We sought to compare usage patterns of laryngeal botulinum toxin injections for voice disorders and to identify and quantify inefficiencies and barriers in providing this treatment. A 26 item survey was written and approved for distribution by the American Academy of Otolaryngology-Head and Neck Surgery and the National Spasmodic Dysphonia Association. It was distributed to...
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The Space Shuttle orbiter lifted off for the last time in July 2011. (NASA/Bill Ingalls/)If all goes according to plan tomorrow, two NASA astronauts will blast off on a SpaceX Falcon 9 rocket from Florida, bound for the International Space Station (ISS). It will be the first crewed launch from US soil since 2011, when the Space Shuttle orbiter made its last flight.When the Shuttle made its debut on the Kennedy Space Center launchpad in 1981, it had two astronauts on board. Up to that point, NASA...
An uptick in cases in some US states is just one of the dire updates on the current pandemic front. (Pixabay/)Follow all of PopSci’s COVID-19 coverage here, including tips on cleaning groceries, ways to tell if your symptoms are just allergies, and a tutorial on making your own mask.We’ve made it through what’s probably been one of the strangest Memorial Day weekends of our lives. As we ease into the summer months, it’s hard to predict what a season of watermelon eating, pool parties, and barbecuing...
You too can have secret powers. (Amazon/)Multi-tools feel like secret weapons; they’re a practical solution to all sorts of problems that pop up during everyday life. While you probably won’t (we hope) have to use one to escape from a locked room, or cut the wires of a covert device that has your highly classified chemistry lab under surveillance, the possibility of MacGyver-ing your way out of a scrape is part of the allure. These cleverly-designed standouts will help you feel ready to handle whatever...
Time to create. (Jakub Dziubak via Unsplash/)Much can be said about the effects of technology on popular music over the years, but few inventions were as pivotal to the progression of modern music as the introduction of the synthesizer. This computerized, electronic instrument made its way into music from every corner of the globe and allowed widespread access to never-before-heard instrumental sounds that have since become touchstones of pop culture. In recent years, new synthesizers have taken...
A stunningly simple solution. (Nadine Shaabana via Unsplash/)Frequent online video meetings are a side-effect of working from home that not everyone loves, and can be downright exhausting. On top of the challenges of getting a word in without being able to make direct eye contact, most of us are constantly distracted by our own faces staring back at us. You can’t just time your meetings for when you can sit in an ethereal beam of diffused sunlight, but there’s no denying the harsh realities of too-little...
Monty Hall hosted about 4,500 episodes of the TV game show Let's Make a Deal over two decades. (Brian Klutch/)We know you are bored at home right now—we are too. Here are some puzzles and brainteasers to challenge your family and friends with, either in person or over video chat. From the 1960s to the ’80s, Monty Hall, host of Let’s Make a Deal, presented this puzzle: Players had to choose among three doors. Two hid a gag gift (like a goat); the third, a prize (say, a car). Simple, but the game...
Some apps let you contact emergency services with a simple, discreet tap. (Uber/)The apps you use every day can keep you safe—whether you're on a date you've arranged online, calling a car, arranging to pick up something you've purchased on the web, or simply messaging other people.You shouldn’t panic about getting into trouble in these scenarios, but you should absolutely make sure you’re aware of each app’s available safety features, just in case you need to use them.UberIt’s in Uber’s best interests...
Greenland glacier; 29 April 2019. <br> Today, more than 700 orbiting objects watch Earth all the time, some continually producing images. (European Space Agency/)The snow hasn’t started yet this October evening in Boulder, Colorado, but the sharp wind and low clouds around Backcountry Pizza & Tap House foretell an early winter storm. Just before 6 p.m., Diane Fritz comes in from the cold, passing pinball machines and pool tables on her way to the back room. Setting down her bag, she takes...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,