How Face Masks Affect Acoustic and Auditory Perceptual Characteristics of the Singing Voice

xlomafota13 shared this article with you from Inoreader How Face Masks Affect Acoustic and Auditory Perceptual Characteristics of the Singing Voice Via Journal of Voice Wearing a face mask has been accepted as one of the most effective ways for slowing the spread of COVID-19. Yet information regarding the degree to which masks affect acoustics and perception associated with voice performers is scarce. This study examines these effects with common face masks, namely a neck gaiter, disposable surgical mask, and N95 mask, as well as a novel material that could be used as a mask (acoustic foam). A recorded excerpt from the "Star-Spangled Banner" was played through a miniature speaker placed inside the mouth of a masked manikin. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

A novel seven‑gene panel predicts prognosis of head and neck squamous cell carcinoma treated with platinum‑based radio(chemo)therapy

xlomafota13 shared this article with you from Inoreader A novel seven‑gene panel predicts prognosis of head and neck squamous cell carcinoma treated with platinum‑based radio(chemo)therapy Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Mar 26. doi: 10.1007/s00405-021-06760-2. Online ahead of print. NO ABSTRACT PMID:33770246 | DOI:10.1007/s00405-021-06760-2 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Bilateral Chronic Subdural Hematomas

xlomafota13 shared this article with you from Inoreader Bilateral Chronic Subdural Hematomas Via leak of cerebrospinal fluid No Shinkei Geka. 2021 Mar;49(2):238-243. doi: 10.11477/mf.1436204384. ABSTRACT Chronic subdural hematomas(SDHs)do not infrequently present isodensity on CT. They should not be overlooked, particularly if bilateral. Therefore, checking for an abnormal mass effect and visualizing the cortical sulci in higher slices should be routine. In suspected cases, MRI can be a reliable tool for establishing the diagnosis. SDHs or subdural hygromas are often found in patients with intracranial hypotension, along with other findings such as thickened dural enhancement, enlarged dural sinuses, an anterior shift of the brainstem, inferior shift of the cerebellar tonsils, and others. In such cases, some techniques are indicated for visualizing cerebrospinal fluid leakage from the dural sac. Conditions with similar imaging findings, such as chronic SDHs, include dural metastases, several kinds of granulomatous disease, and hypertrophic pachymeningitis. Addition ally, it is essential to consider child abuse when SDH is found in children. PMID:33762443 | DOI:10.11477/mf.1436204384 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Endonasale konfokale Laserendomikroskopie – erste Anwendung und Validierung von Malignitätskriterien

xlomafota13 shared this article with you from Inoreader Endonasale konfokale Laserendomikroskopie – erste Anwendung und Validierung von Malignitätskriterien Via Laryngo-Rhino-Otologie Laryngorhinootologie DOI: 10.1055/a-1418-9175 Hintergrund Die konfokale Laserendomikroskopie (CLE) ist eine Methode zur In-vivo-Echtzeit-Visualisierung von Schleimhautveränderungen auf zellulärer Ebene. Erste Untersuchungen bei Kopf-Hals-Karzinomen beschrieben die oropharyngeale Anwendbarkeit. Ziel dieser Untersuchung ist es, anhand der im Oropharynx validierten Kriterien zu klären, ob diese auf die endonasalen Schleimhäute übertragen werden können. Methode Wir verwendeten die CLE mit intravenöser Fluorescein-Färbung vor und während der endoskopischen Operation bei einem Patienten mit einem sinunasalen invertierten Papillom sowie einem Patienten mit einem endonasalen Plattenepithelkarzinom. Wir verglichen die zelluläre Darstellung der pathologischen Veränderungen mit der der gesunden Schleimhaut der Gegenseite desselben Patienten sowie mit unseren früheren Befunden im Oropharynx. Ergebnisse Die endonasale CLE erwies sich als im operativen Setting gut durchführbar und die Übertragung von Malignitätskriterien in Analogie zur histologischen Untersuchung konnte optisch gut nachvollzogen werden. Darüber hinaus ergaben sich zusätzliche Kriterien zur geweblichen Dignitätsbeurteilung. Schlussfolgerung Unsere Ergebnisse legen nahe, dass die endonasale CLE eine wertvolle Erweiterung des diagnostischen Repertoires durch eine zusätzliche Echtzeitanalyse der Nasenschleimhaut darstellt. Dies ist von besonderem Wert in chirurgisch anspruchsvollen anatomischen Bereichen wie den Nasennebenhöhlen. Weitere Untersuchungen und eine Validierung dieser Ergebnisse werden notwendig sein, um die Sicherheit der Methode beurteilen zu können. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Management of Lingual Thyroid with Second Thyroid Anomaly: An Institutional Experience

xlomafota13 shared this article with you from Inoreader Management of Lingual Thyroid with Second Thyroid Anomaly: An Institutional Experience Via Otolaryngology Indian Abstract Patients diagnosed with Lingual thyroid (LT) may have second thyroid anomaly (STA).Given rarity of dual ectopics/anomalies, standardized management recommendations are lacking. We aimed to describe our experience in management of LT with STA and suggest a management algorithm. We conducted a retrospectivechart review of patients diagnosed with LT between Jul-2013 and Dec-2019. Data regarding demographics, clinical presentation, endocrine-profile, associated STA treatment received, and outcomes were collected and analyzed. Eight patients (female-7 cases, male-1 case, adult-4 cases, children-4 cases, mean age-18.1 years, range 6–43 years) with LT were identified. Four(50%) cases had STA in addition to LT (thyroglossal cyst in two-cases, sublingual thyroid in one-case and sub-mental thyroid in one-case) and presented as neck mass. Diagnosis was confirmed with flexible-nasopharyngoscopy,ultrasonography,thyroid-scintigraphy and computed-tomography. Ectopic thyroid(s) was/were only functional thyroid gland with absence of normal thyroid in all cases. Two- cases had symptomatic for LT and were managed by coblation assisted excision of LT in one and I131 ablation in one-case.All adult patients were hypothyroidand received thyroxin.All pediatric cases were euthyroidand received no surgical intervention for LT.Three patients required surgery for STA; Sistrunk surgery in two and excision of submental thyroid in one. All cases were asymptomatic. These results were utilized to suggest a management algorithm for LT with STA. LT patients with STA are more symptomatic and required more surgical interventions in compare to isolated LT. When appropriate, excision of STA with/without intervention for LT and thyroxin is advocated as the treatment modality of choice in LT patients with STA. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Application of auriculotemporal nerve block and dextrose prolotherapy in exercise therapy of TMJ closed lock in adolescents and young adults

xlomafota13 shared this article with you from Inoreader Application of auriculotemporal nerve block and dextrose prolotherapy in exercise therapy of TMJ closed lock in adolescents and young adults Via Head & Face Medicine Temporomandibular joint (TMJ) 'closed lock' is a clinical condition causing TMJ pain and limited mouth opening (painful locking). Recent studies suggest an increasing prevalence of degenerative joint disease a... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Tympanic membrane perforations: a critical analysis of 1003 ears and proposal of a new classification based on pathogenesis

xlomafota13 shared this article with you from Inoreader Tympanic membrane perforations: a critical analysis of 1003 ears and proposal of a new classification based on pathogenesis Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Mar 27. doi: 10.1007/s00405-021-06776-8. Online ahead of print. ABSTRACT PURPOSE: To present a large series ears with tympanic membrane perforations (TMP), to describe their characteristics, and to propose a new classification system based on the pathogenesis of TMP. METHODS: This cross-sectional study was conducted at a tertiary university hospital with 1003 ears (792 consecutive patients with TMP in at least 1 ear). Otoendoscopy and audiometry were performed. Perforation measurements and their locations were digitally assessed. TMP with no suggestive signs of previous retraction were classified as Group 1, and those with possible previous retraction were classified as Group 2. Signs of retraction previous to the TMP, symptom length, perforation size and location, status of the contralateral ear, and hearing status were compared. RESULTS: Group 1 comprised 63.5% of the included ears. Compare d to Group 2, Group 1 presented a higher rate of central perforations (99% vs. 53%), a shorter duration of symptoms, smaller perforations (mean area: 18.5% vs. 41.4%), a higher rate of perforations in the anterior quadrants, better hearing levels (mean tritonal gap: 23.9 dB vs. 29.2 dB), and a lower rate of abnormal contralateral ears (28% vs. 66%). CONCLUSION: The classification of TMP into two groups based on signs of previous retractions is feasible and indicates two different levels of disease severity. While the group without previous signs of retraction comprises ears with more limited disease, membranes with previous retraction seem to show more severe disease and, consequently, a less functional middle ear. PMID:33772610 | DOI:10.1007/s00405-021-06776-8 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The protective effect of Naringenin against ovalbumin-induced allergic rhinitis in rats

xlomafota13 shared this article with you from Inoreader The protective effect of Naringenin against ovalbumin-induced allergic rhinitis in rats Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Mar 26. doi: 10.1007/s00405-021-06769-7. Online ahead of print. ABSTRACT BACKGROUND: Allergic rhinitis (AR) is a ubiquitous chronic disease with a growing incidence. We aimed to investigate the protective effect of naringenin against AR induced in rats. METHODS: Thirty-two Sprague Dawley rats were divided into four groups of eight animals each. Group 1 represented the control group. The other 24 rats were sensitized with intraperitoneal 0.3 mg ovalbumin (OVA) and 30 mg aluminum hydroxide every other day for 14 days to induce AR. Ten microliters OVA was administered to both nostrils by inhalation for the following seven days to provoke AR. Group 2 represented the AR group and received no treatment. Group 3 was treated as the reference group and received 5 mg/kg desloratadine every day between days 15 and 21. Group 4 received 100 mg/kg naringenin orally between days 15 and 21. All animal's sneezing a nd nasal itching scores were recorded on day 22. The rats were then sacrificed. Serum total IgE, IL4 and IL5 values were studied, and nasal structures were extracted 'en bloc' for histopathological examination. RESULTS: Significant clinical recovery was achieved in the group treated with naringenin. Serum total IgE, IL4 and IL5 values in the naringenin group were significantly lower than in the AR group, and significant histopathological improvement was observed compared to the AR group. CONCLUSIONS: Naringenin produced significant clinical, biochemical and histopathological benefits in rats with induced AR. These effects suggest that naringenin is a promising agent for the treatment of AR. PMID:33772317 | DOI:10.1007/s00405-021-06769-7 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Lacrimal sac diverticulum: clinical presentation and endoscopic management

xlomafota13 shared this article with you from Inoreader Lacrimal sac diverticulum: clinical presentation and endoscopic management Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Mar 27. doi: 10.1007/s00405-021-06773-x. Online ahead of print. ABSTRACT BACKGROUND: To describe the clinical presentation, surgical intervention and clinical outcomes of patients with a lacrimal sac diverticulum. METHODS: Retrospective chart review of all patients who underwent endonasal endoscopic dacryocystorhinostomy (DCR) in a single medical center from January 2010 to October 2020. The diagnosis of a lacrimal sac diverticulum was based upon intraoperative findings. RESULTS: In total, 406 patients underwent endonasal endoscopic DCR during the study period. Eight female patients (mean age 35 years) were diagnosed with a lacrimal diverticulum and underwent DCR by an endonasal endoscopic approach. The mean follow-up period was 11.5 months. All eight patients had cystic findings at the lacrimal fossa on imaging studies prior to surgery. Five patients had a history of dacryocystitis. The main presenting symptoms were epiphora and/or medial canthal swelling. The diverticulum was identified on the inferior wall in seven cases. A dacryolith in the lacrimal sac was identified intraoperatively in two patients. All patients showed full resolution of symptoms after surgery. There were no intraoperative or postoperative complications. CONCLUSION: Lacrimal sac diverticulum is a rare entity with female predominance. It may be the underlying etiology of epiphora and/or dacryocystitis. The diagnosis is based upon identifying the presence of a diverticulum intraoperatively. Endoscopic DCR is an effective approach for integrating both the lacrimal sac and diverticulum cavities into a single space, leading to resolution of symptoms. PMID:33772319 | DOI:10.1007/s00405-021-06773-x View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Challenging the gold standard: methods of sampling for microbial culture in patients with chronic rhinosinusitis

xlomafota13 shared this article with you from Inoreader Challenging the gold standard: methods of sampling for microbial culture in patients with chronic rhinosinusitis Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Mar 27. doi: 10.1007/s00405-021-06747-z. Online ahead of print. ABSTRACT PURPOSE: Chronic rhinosinusitis (CRS) is a highly prevalent multifactorial disorder. Culture-directed antibiotics are frequently prescribed to patients with CRS and the middle nasal meatus (MM) is traditionally believed to be a representative sampling site of the sinuses as a whole. The purpose of our study was to reevaluate the reliability of the MM as a sampling site in patients with CRS who suffer from impaired drainage from the sinuses to the MM. METHODS: Swabs and tissue biopsies were collected from the MM, maxillary sinus and frontal sinus from 50 patients with CRS. The results of bacterial culture were compared between sampling methods and sites in relation to the patency of the sinus ostia. RESULTS: 782 bacterial isolates were cultured from the samples. Concordant results between the MM and the sinus cavity were noted in 80% of patients for the maxillary sinus, but only 66% for the frontal sinus and 76% for the sinuses a whole. The differences were similarly prevalent in patients with open and occluded sinus ostia. Notably, swabs from all three sites provided representative information in 92% of patients and tissue biopsies did not provide additional information compared to multiple swabs. CONCLUSION: The traditional method of sampling from the middle meatus provides inadequate information in 24% of patients with CRS, which may result in inadequate antibiotic therapy and contribute to increasing antibiotic resistance. Additional sampling from the sinuses should be recommended whenever possible, while invasive sampling is not necessary. PMID:33772608 | DOI:10.1007/s00405-021-06747-z View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Patterns of cervical lymph node metastasis in supraglottic laryngeal cancer and therapeutic implications of surgical staging of the neck

xlomafota13 shared this article with you from Inoreader Patterns of cervical lymph node metastasis in supraglottic laryngeal cancer and therapeutic implications of surgical staging of the neck Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Mar 27. doi: 10.1007/s00405-021-06753-1. Online ahead of print. ABSTRACT PURPOSE: Accurate therapeutic management of the neck is a challenge in patients with supraglottic laryngeal cancer. Nodal metastasis is common at all disease stages, and treatment planning relies on clinical staging of the neck, for both surgical and non-surgical treatment. Here, we compared clinical and surgical staging results in supraglottic carcinoma patients treated with primary surgery to assess the accuracy of pre-therapeutic clinical staging and guide future treatment decisions. METHODS: Retrospective analysis of clinical, pathological, and oncologic outcome data of 70 patients treated with primary surgery and bilateral neck dissection for supraglottic laryngeal cancer. Patients where clinical and pathological neck staging results differed, were identified and analyzed in detail. RESULTS: On pathologic assessment , patients with early stage (pT1/2) primaries showed cervical lymph node metastases in 55% (n = 17/31) of cases, compared to 67% (n = 26/39) of patients with pT3/4 tumors. In 24% (n = 17/70) of all patients, cN status differed from pN status, resulting in an upstaging in 16% of cases (n = 11/70) and a downstaging in 9% (n = 6/70) of cases. 14% of patients with cN0 status had occult metastases (n = 5/30). As assessed by a retrospective tumor board, in case of a non-surgical treatment approach, the inaccurate clinical staging of the neck would have led to an over- or undertreatment of the neck in 20% (n = 14/70) of all patients. CONCLUSION: Our data re-emphasize the high cervical metastasis rates of supraglottic laryngeal cancer across all stages. Inaccurate clinical staging of the neck is common and should be taken into consideration when planning treatment. PMID:33772318 | DOI:10.1007/s00405-021-06753-1 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.