Benefits of positron emission tomography scans for the evaluation of radiotherapy. Cancer Radiother. 2020 May 21;: Authors: Decazes P, Thureau S, Modzelewski R, Damilleville-Martin M, Bohn P, Vera P Abstract The assessment of tumour response during and after radiotherapy determines the subsequent management of patients (adaptation of treatment plan, monitoring, adjuvant treatment, rescue treatment or palliative care). In addition to its role in extension...
Tue May 26, 2020 13:19
Surgical sequence of neck dissection and primary tumor excision could impact the locoregional recurrence rates in oral squamous cell carcinoma. Oral Oncol. 2020 May 21;:104809 Authors: Devaraja K PMID: 32448740 [PubMed - as supplied by publisher]
Tue May 26, 2020 13:19
Impact of changes in head position during head and neck surgery on the depth of tracheal tube intubation in anesthetized children. BMC Anesthesiol. 2020 May 24;20(1):124 Authors: Yan S, Zhang H Abstract BACKGROUND: The classic formula has been used to estimate the depth of tracheal tube intubation in children for decades. However, it is unclear whether this formula is applicable when the head and neck position changes intraoperatively. ...
Tue May 26, 2020 13:19
Related ArticlesHuman vestibulo-ocular reflex adaptation is frequency selective. J Neurophysiol. 2019 09 01;122(3):984-993 Authors: Rinaudo CN, Schubert MC, Figtree WVC, Todd CJ, Migliaccio AA Abstract The vestibulo-ocular reflex (VOR) is the only system that maintains stable vision during rapid head rotations. The VOR gain (eye/head velocity) can be trained to increase using a vestibular-visual mismatch stimulus. We sought to determine whether low-frequency...
Tue May 26, 2020 13:19
Related ArticlesA quantitative confidence signal detection model: 2. Confidence analysis. J Neurophysiol. 2019 09 01;122(3):904-921 Authors: Yi Y, Wang W, Merfeld DM Abstract Decision making is a fundamental subfield within neuroscience. While recent findings have yielded major advances in our understanding of decision making, confidence in such decisions remains poorly understood. In this paper, we present a confidence signal detection (CSD) model...
Tue May 26, 2020 13:19
Related ArticlesThe hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the Osteoporotic Fractures in Men Study and the Sleep Heart Health Study. Eur Heart J. 2019 04 07;40(14):1149-1157 Authors: Azarbarzin A, Sands SA, Stone KL, Taranto-Montemurro L, Messineo L, Terrill PI, Ancoli-Israel S, Ensrud K, Purcell S, White DP, Redline S, Wellman A Abstract AIMS: Apnoea-hypopnoea index (AHI), the universal clinical metric of...
Tue May 26, 2020 13:18
The Precautions Required for the Safe Return of Elective Surgery - A Letter to the Editor in Response to "Impact of the coronavirus (COVID-19) pandemic on surgical practice - Part 2 (surgical prioritisation)". Int J Surg. 2020 May 22;: Authors: Cheng SO, Liu A PMID: 32450264 [PubMed - as supplied by publisher]
Tue May 26, 2020 13:18
Letter to editor - Can universal masking help with our recovery from the COVID-19 pandemic? Int J Surg. 2020 May 22;: Authors: Chiang CH, Chiang CH, Chiang CH PMID: 32450263 [PubMed - as supplied by publisher]
Tue May 26, 2020 13:18
An Invited Commentary on "Reducing the negative appendectomy rate with the laparoscopic appendicitis score; a multicenter prospective cohort and validation study" (Int J Surg 2020; Epub ahead of print). Int J Surg. 2020 May 22;: Authors: Iuamoto LR, Meyer A PMID: 32450262 [PubMed - as supplied by publisher]
Tue May 26, 2020 13:18
A Commentary on "Enhanced recovery after surgery protocols in patients undergoing liver transplantation: A retrospective comparative cohort study" (Int J Surg 2020;78:108-22). Int J Surg. 2020 May 22;: Authors: Qiang H, Yuanshui S PMID: 32450261 [PubMed - as supplied by publisher]
Tue May 26, 2020 13:18
A Commentary on ''Major Hepatectomies in Liver Cystic Echinococcosis: A Bi-centric experience. Retrospective Cohort Study'' (Int J Surg 2018;54:182-6). Int J Surg. 2020 May 22;: Authors: Akbulut S, Sahin TT, Yilmaz S PMID: 32450260 [PubMed - as supplied by publisher]
Tue May 26, 2020 13:18
An Invited Commentary on: The incidence of right-sided colon cancer in patients aged over 40 years with acute appendicitis: A systematic review and meta-analysis. Int J Surg. 2020 May 22;: Authors: Caputo D, Coppola A PMID: 32450259 [PubMed - as supplied by publisher]
Tue May 26, 2020 13:18
In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies. Bioorg Chem. 2020 May 16;100:103951 Authors: Fayed EA, Ammar YA, Ragab A, Gohar NA, Mehany ABM, Farrag AM Abstract In this study, anti-proliferative effects of twenty-seven indeno[1,2-b]quinoxalin-11-one derivatives were investigated in three human cancer cell lines, namely: the colon cancer cell line...
Tue May 26, 2020 13:15
Unravelling the anticancer potential of functionalized chromeno[2,3-b]pyridines for breast cancer treatment. Bioorg Chem. 2020 May 17;100:103942 Authors: Oliveira-Pinto S, Pontes O, Lopes D, Sampaio-Marques B, Costa MD, Carvalho L, Gonçalves CS, Costa BM, Maciel P, Ludovico P, Baltazar F, Proença F, Costa M Abstract A selection of new chromeno[2,3-b]pyridines was prepared from chromenylacrylonitriles and N-substituted piperazines, using a novel and...
Tue May 26, 2020 13:15
Metabolomics study of the metabolic changes in hepatoblastoma cells in response to NTCP/SLC10A1 overexpression. Int J Biochem Cell Biol. 2020 May 22;:105773 Authors: Wang J, Tian R, Shan Y, Li J, Gao H, Xie C, Ma Y, Wu Y, Ji B, Gu S, Xu M Abstract NTCP (SLC10A1) has been well recognized as a basolateral (sinusoidal) Na+-bile acid co-transporter that mediates the hepatic uptake of bile acids. However, little is known about the effects of NTCP (SLC10A1)...
Tue May 26, 2020 13:15
Long non-coding RNA SLC16A1-AS1: its multiple tumorigenesis features and regulatory role in cell cycle in oral squamous cell carcinoma. Cell Cycle. 2020 May 25;:1-13 Authors: Feng H, Zhang X, Lai W, Wang J Abstract Altered expressions of long non-coding RNAs (lncRNAs) are potential cancer prognostic biomarkers that play a critical role in the development of tumorigenesis and metastasis of cancer. However, the relationship between the expression of...
Tue May 26, 2020 13:15
Entinostat is a Novel Therapeutic Agent to Treat Oral Squamous Cell Carcinoma. J Oral Pathol Med. 2020 May 25;: Authors: Marques AEM, do Nascimento Filho CHV, Marinho TMB, Guerra ENS, Castilho RM, Squarize CH Abstract INTRODUCTION: Alterations of the epigenome may influence cancer initiation and progression. At the cellular level, histones are key regulators of chromatin accessibility and gene transcription; thus, inhibition of histone deacetylase...
Tue May 26, 2020 13:15
Anticancer effects of brusatol in nasopharyngeal carcinoma through suppression of the Akt/mTOR signaling pathway. Cancer Chemother Pharmacol. 2020 May 24;: Authors: Guo S, Zhang J, Wei C, Lu Z, Cai R, Pan D, Zhang H, Liang B, Zhang Z Abstract PURPOSE: Brusatol, a natural quassinoid that is isolated from a traditional Chinese herbal medicine known as Bruceae Fructus, possesses biological activity in various types of human cancers, but its effects...
Tue May 26, 2020 13:15
Selective Induction of Cellular Toxicity and Anti-tumor Efficacy by N-Methylpiperazinyl Diarylidenylpiperidone and its Pro-nitroxide Conjugate through ROS-mediated Mitochondrial Dysfunction and G2/M Cell-cycle Arrest in Human Pancreatic Cancer. Cell Biochem Biophys. 2020 May 24;: Authors: Mast JM, Hinds JW, Tse D, Axelrod K, Kuppusamy ML, Kmiec MM, Bognár B, Kálai T, Kuppusamy P Abstract Pancreatic adenocarcinoma is an aggressive cancer with poor...
Tue May 26, 2020 13:15
Structural insight into the interaction between p53 TAD1 and AIMP2-DX2 by NMR. Biochem Biophys Res Commun. 2020 May 21;: Authors: Cho HY, Jha R, Mushtaq AU, Oh SH, Jeon YH Abstract p53 is the most studied tumor suppressor and a key transcriptional factor, with discrete domains that regulate cellular pathways such as apoptosis, angiogenesis, cell-cycle arrest, DNA repair, and senescence. Previous studies have suggested that AIMP2, and ARS-interacting...
Tue May 26, 2020 13:15
Corrigendum to "The long non-coding RNA HOTAIR promotes the proliferation of serious ovarian cancer cells through the regulation of cell cycle arrest and apoptosis" [Exp. Cell Res. 333 (2015) 238-248]. Exp Cell Res. 2020 May 21;:112035 Authors: Qiu JJ, Wang Y, Ding JX, Jin HY, Yang G, Hua KQ PMID: 32448483 [PubMed - as supplied by publisher]
Tue May 26, 2020 13:15
Distinct anti-proliferative effects of herbal melanin on human acute monocytic leukemia THP-1 cells and embryonic kidney HEK293 cells. BMC Complement Med Ther. 2020 May 24;20(1):154 Authors: El-Obeid A, Alajmi H, Harbi M, Yahya WB, Al-Eidi H, Alaujan M, Haseeb A, Trivilegio T, Alhallaj A, Alghamdi S, Ajlouni AW, Matou-Nasri S Abstract BACKGROUND: Herbal melanin (HM) is a dark pigment extracted from the seed coat of Nigella sativa L. and known to...
Tue May 26, 2020 13:15
Ribophorin II is upregulated in myelodysplastic syndromes and prevents apoptosis and cell cycle progression. Exp Biol Med (Maywood). 2020 May 25;:1535370220927996 Authors: Ren J, Wang Y, Wang L, Guo X, Guo X Abstract IMPACT STATEMENT: This study explored the role of ribophorin II (RPN2) in myelodysplastic syndromes (MDSs) cell proliferation and growth and revealed that RPN2 knockdown suppressed OCI-AML3 cell growth and proliferation and triggered...
Tue May 26, 2020 13:15
Related ArticlesBlockade of TLR4 using TAK-242 (resatorvid) enhances anti-cancer effects of chemotherapeutic agents: a novel synergistic approach for breast and ovarian cancers. Immunol Res. 2019 12;67(6):505-516 Authors: Kashani B, Zandi Z, Karimzadeh MR, Bashash D, Nasrollahzadeh A, Ghaffari SH Abstract It is believed that pathways of the immune system are responsible for eradicating cancer cells; however, their over-activation and also their ectopic...
Tue May 26, 2020 13:15
Development and validation of criteria for sparing confirmatory tests in diagnosing primary aldosteronism. J Clin Endocrinol Metab. 2020 May 25;: Authors: Wang K, Hu J, Yang J, Song Y, Fuller PJ, Hashimura H, He W, Feng Z, Cheng Q, Du Z, Wang Z, Ma L, Yang S, Li Q Abstract CONTEXT: The Endocrine Society Guidelines for the diagnosis of primary aldosteronism (PA) suggest that confirmatory tests (CFT) are not required when the following criteria are met:...
Tue May 26, 2020 13:13
Expression of SOAT1 in adrenocortical carcinoma and response to mitotane monotherapy: an ENSAT multicenter study. J Clin Endocrinol Metab. 2020 May 25;: Authors: Weigand I, Altieri B, Lacombe AMF, Basile V, Kircher S, Landwehr LS, Schreiner J, Zerbini MCN, Ronchi CL, Megerle F, Berruti A, Canu L, Volante M, Paiva I, Della Casa S, Sbiera S, Fassnacht M, Fragoso MCBV, Terzolo M, Kroiss M Abstract CONTEXT: Objective response rate to mitotane in advanced...
Tue May 26, 2020 13:13
Letter to the Editor: Our Response to Covid-19 as Endocrinologists and Diabetologists. J Clin Endocrinol Metab. 2020 May 25;: Authors: Snyder S PMID: 32448905 [PubMed - as supplied by publisher]
Tue May 26, 2020 13:13
Pulmonary Function in Patients with Multiple Endocrine Neoplasia 2B (MEN2B). J Clin Endocrinol Metab. 2020 May 25;: Authors: Fuller S, Del Rivero J, Venzon D, Ilanchezhian M, Allen D, Folio L, Ling A, Widemann B, Fontana JR, Glod J Abstract CONTEXT: Multiple endocrine neoplasia type 2B (MEN2B) is a rare cancer predisposition syndrome resulting from an autosomal-dominant germline mutation of the RET proto-oncogene. No prior studies have investigated pulmonary...
Tue May 26, 2020 13:13
CPAP Adherence, Mortality, and Progression-Free Survival in Interstitial Lung Disease and OSA. Chest. 2020 May 22;: Authors: Adegunsoye A, Neborak JM, Zhu D, Cantrill B, Garcia N, Oldham JM, Noth I, Vij R, Kuzniar TJ, Bellam SK, Strek ME, Mokhlesi B Abstract BACKGROUND: Obstructive sleep apnea (OSA), a common co-morbidity in ILD, could contribute to a worsened course if untreated. It is unclear if adherence to CPAP therapy improves outcomes. ...
Tue May 26, 2020 13:08
Clinical, esthetic, and quality of life outcomes after telegnathic surgery in Caucasian OSAS patients. Cranio. 2020 May 23;:1-8 Authors: González MB, Casellas JB, Fernández Mondragón MP, Nuño VC, Amezaga JA, De Carlos Villafra F Abstract OBJECTIVE: To carry out both an objective and subjective assessment of the facial esthetics, clinical outcome, and quality of life evaluation in 25 OSAS patients treated with telegnathic surgery. METHODS: Patients...
Tue May 26, 2020 13:08
ABSTRACT Background Podoplanin (PDPN) is a glycoprotein associated with epithelial‐mesenchymal transition, invasion, and metastasis in several types of malignancies, including oral and oropharyngeal squamous cell carcinoma (OSCC). The aim of this systematic review (SR) was to summarize and critically appraise the available evidence about the association between PDPN immunoexpression and clinicopathological features and its utility as a prognostic marker in OSCC. Methods Five electronic...
Mon May 25, 2020 22:44
ABSTRACT Introduction Alterations of the epigenome may influence cancer initiation and progression. At the cellular level, histones are key regulators of chromatin accessibility and gene transcription; thus, inhibition of histone deacetylase enzymes (HDACs) constitutes an attractive target for therapy. In this study, we investigated the effects of the HDAC inhibitor Entinostat on oral squamous cell carcinoma (OSCC). Materials and Methods We tested the effects of Entinostat on OSCC cell...
Mon May 25, 2020 21:39
Abstract Background Preventive and early diagnostic methods such as health promotion and disease screening are increasingly advocated to improve detection and survival rates for oral cancer. These strategies are most effective when targeted at ‘high‐risk’ individuals and populations. Bayesian disease‐mapping modelling is a statistical method to quantify and explain spatial and temporal patterns for risk and covariate factor influence, thereby identifying ‘high‐risk’ sub‐regions or ‘case clustering’...
Mon May 25, 2020 21:14
Abstract Background Synovitis is characterized by the infiltration of inflammatory cells and often accompanies the pathological progression of the clinical symptoms affecting the temporomandibular joint (TMJ), such as pain, snapping, and limited mouth opening. It has been suggested that the signal transduction pathway and resultant proinflammatory mediators play important roles in the pathogenesis of synovitis. Therefore, in this present research, we aimed to investigate the changes in the expressions...
Mon May 25, 2020 14:56
Abstract Background Buccal squamous cell carcinoma (SCC) is a locoregionally aggressive malignancy, representing a small subset of oral cancers in North America. We investigated the prognostic value of several clinicopathologic factors in a cohort of patients diagnosed with buccal SCC. Methods Between years 1992 and 2017, 52 patients were diagnosed with conventional buccal SCC. Archival surgical pathology material was retrospectively reviewed for reportable findings according to the latest...
Mon May 25, 2020 14:39
The magnetic resonance imaging appearances of the interureteric crest of the urinary bladder. Surg Radiol Anat. 2020 May 24;: Authors: Abernethy P, Williams P, Freeman S Abstract PURPOSE: This study was devised to evaluate the imaging appearances of the interureteric crest (IUC) of the bladder on magnetic resonance imaging (MRI). The primary objective was to determine how commonly the IUC was observed on pelvic MRI examinations. The secondary objectives...
Tue May 26, 2020 13:01
The frequency-following response (FFR) is an EEG-based potential used to characterize the brainstem encoding of complex sounds. Adopting techniques from auditory signal processing, we assessed the degree to which FFRs encode important properties of cochlear processing (e.g. nonlinearities) and their relation to speech-in-noise (SIN) listening skills. Based on the premise that normal cochlear transduction is characterized by rectification and compression, we reasoned these nonlinearities would create...
Mon May 25, 2020 03:00
Waggle needling, a classical anti-spastic needling technique characterized by combination of acupuncture with joint movement, has gained increasing popularity of spasticity treatment in China. This study was designed to compare the anti-spastic effect of waggle needling to the routine needling and to explore its underlying mechanism. We established post-stroke spasticity model based on ischemia stroke operation (middle cerebral artery occlusion). Rats were divided into six groups: normal control...
Mon May 25, 2020 03:00
The brain’s default mode network (DMN) has become closely associated with self-referential mental activity, particularly in the resting-state. Prior reports point that the sex hormones are potent modulators of brain plasticity and functional connectivity. However, it is uncertain whether changes in ovarian hormones, as occur during the monthly menstrual cycle, substantially affects the functional connectivity of DMN. Here, we employed a Self-Awareness Scale (SAS) and the resting-state functional...
Mon May 25, 2020 03:00
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,