Αρχειοθήκη ιστολογίου

Τρίτη 26 Μαΐου 2020


Single cell transcriptomics reveals opioid usage evokes widespread suppression of antiviral gene program
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16159-yOver 100 million of opioid prescriptions are issued yearly in the USA alone, but the impact of opioid use on the immune system is barely characterized. Here the authors report antiviral immune response is blunted in several types of blood cells from opioid-dependent individuals, and when healthy donor cells are exposed to morphine in a dish.
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
The Perlman syndrome DIS3L2 exoribonuclease safeguards endoplasmic reticulum-targeted mRNA translation and calcium ion homeostasis
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16418-yThe DIS3L2 exonuclease degrades aberrant 7SL RNAs tagged by an oligouridine 3′-tail. Here the authors analyze DIS3L2 knockout mouse embryonic stem cells and suggest that DIS3L2-mediated quality control of 7SL RNA is important for ER-mediated translation and calcium ion homeostasis.
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Magnetic cilia carpets with programmable metachronal waves
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16458-4Synthetic hair-like structures (cilia) controlled by an external field have been developed, especially for microfluidic applications. Here, Gu et al. make soft artificial cilia carpets with programmable magnetization patterns and utilize them to achieve pumping and locomotion in a soft robotic model.
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16439-7Due to poor specificity, the current pharmacotherapy of atherosclerosis has limited therapeutic efficacy. Here, the authors show that a macrophage-biomimetic nanomedicine effectively alleviates atherosclerosis via targeted pharmacotherapy and sequestration of proinflammatory cytokines and chemokines.
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Structural basis for effector protein recognition by the Dot/Icm Type IVB coupling protein complex
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16397-0The Legionella pneumophila Dot/Icm type IVB secretion system (T4BSS) translocates effector proteins into host cells, and the recognition of these effectors is mediated by the Dot/Icm type IV coupling protein (T4CP) complex. Here, the authors present the crystal structure of a four-subunit containing T4CP subcomplex bound to the effector protein VpdB, and identify a FxxxLxxxK binding motif that is present in a subset...
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Tuning the interfacial spin-orbit coupling with ferroelectricity
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16401-7The spin Hall angle (SHA) is a measure of the efficiency for converting a charge to a spin current is still challenging to tune in situ. Here, the authors demonstrate by introducing a ferroelectric (FE) material in a ferromagnetic/heavy metal stack the SHA can be voltage controled via the polarization of the FE layer.
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Enabling safe aqueous lithium ion open batteries by suppressing oxygen reduction reaction
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16460-wDespite the non-flammable nature of water-based electrolytes, aqueous lithium-ion batteries still carry an explosion risk due to the sealing structure. Here the authors report a safe aqueous battery with an open configuration, utilizing highly concentrated electrolytes and Al2O3 coated anodes.
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-15701-2The tau protein is theorized to spread transneuronally in Alzheimers disease, though this theory remains unproven in humans. Our simulations of epidemic-like protein spreading across human brain networks support this theory, and suggest the spreading dynamics are modified by β-amyloid
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Single cell transcriptomics reveals opioid usage evokes widespread suppression of antiviral gene program
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
The Perlman syndrome DIS3L2 exoribonuclease safeguards endoplasmic reticulum-targeted mRNA translation and calcium ion homeostasis
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Magnetic cilia carpets with programmable metachronal waves
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Structural basis for effector protein recognition by the Dot/Icm Type IVB coupling protein complex
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Tuning the interfacial spin-orbit coupling with ferroelectricity
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Enabling safe aqueous lithium ion open batteries by suppressing oxygen reduction reaction
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease
Nature Communications - current - nature.com science feeds
Tue May 26, 2020 03:00
Factors affecting GDI improvement after single event multilevel surgery in patients with cerebral palsy
Publication date: Available online 25 May 2020Source: Gait & PostureAuthor(s): Jae Jung Min, Soon-Sun Kwon, Ki Hyuk Sung, Kyoung Min Lee, Chin Youb Chung, Moon Seok Park
Gait & Posture
Tue May 26, 2020 19:43
Utilizing the Somatosensory System via Vibratory Stimulation to Mitigate Knee Pain during Walking: Randomized Clinical Trial
Publication date: Available online 25 May 2020Source: Gait & PostureAuthor(s): Arielle G. Fischer, Jennifer C. Erhart-Hledik, Jessica L. Asay, Constance R. Chu, Thomas P. Andriacchi
Gait & Posture
Tue May 26, 2020 19:43
Verification of reliability and validity of motion analysis systems during bilateral squat using human pose tracking algorithm
Publication date: Available online 25 May 2020Source: Gait & PostureAuthor(s): Megumi Ota, Hiroshige Tateuchi, Takaya Hashiguchi, Takehiro Kato, Yasuhiro Ogino, Momoko Yamagata, Noriaki Ichihashi
Gait & Posture
Tue May 26, 2020 19:43
Midstance hamstring length is a better indicator for hamstring lengthening procedures than initial contact length
Publication date: Available online 25 May 2020Source: Gait & PostureAuthor(s): Sam Augsburger, Hank White, Henry Iwinski
Gait & Posture
Tue May 26, 2020 19:43
Classifying individuals with and without Patellofemoral Pain Syndrome using ground force profiles – development of a method using functional data boosting
Publication date: Available online 25 May 2020Source: Gait & PostureAuthor(s): Bernard X.W. Liew, David Rugamer, Deepa Abichandani, Alessandro Marco De Nunzio
Gait & Posture
Tue May 26, 2020 19:43
Head orientation and gait stability in young adults, dancers and older adults
Publication date: Available online 25 May 2020Source: Gait & PostureAuthor(s): Rina M. Magnani, Sjoerd M. Bruijn, Jaap H. van Dieën, Marcus F. Vieira
Gait & Posture
Tue May 26, 2020 19:43
Correction of out-of-FOV motion artifacts using convolutional neural network
Publication date: Available online 25 May 2020Source: Magnetic Resonance ImagingAuthor(s): Chengyan Wang, Yuan Wu, Yiping P. Du
Magnetic Resonance Imaging
Tue May 26, 2020 19:37
Polymorphism of <em>TNFRSF1A</em> gene may act as predictor of severe radiation-induced oral mucositis and prognosis factor in head and neck cancer patients
Publication date: Available online 26 May 2020Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Radosław Mlak, Tomasz Powrózek, Anna Brzozowska, Iwona Homa-Mlak, Marcin Mazurek, Paweł Gołębiowski, Dorota Korzeb, Mansur Rahnama-Hezavah, Teresa Małecka-Massalska
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Tue May 26, 2020 19:35
Distal Renal Artery Aneurysm Repair: “More than Meets the Eye”
Publication date: Available online 25 May 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Miltiadis Matsagkas, George Kouvelos
ScienceDirect Publication: European Journal of Vascular and Endovascular Surgery
Tue May 26, 2020 19:12
Limb Salvage: The Heart and Soul of Vascular Surgery
Publication date: Available online 25 May 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Christian-Alexander Behrendt, Eike S. Debus
ScienceDirect Publication: European Journal of Vascular and Endovascular Surgery
Tue May 26, 2020 19:12
Rethinking Respiratory Function Test Lab in the Era of COVID-19 : considerations about the “today” and the “day after”
The 2020 Members of Proficiency Standards for Pulmonary Function Testing Committee of the American Thoracic Society recently raised concerns on pulmonary function testing (PFT) “as a potential avenue for COVID 19 transmission due to the congregation of patients with lung disease and because of the potential for coughing and droplet formation”. (1) The Committee reccommen-ded that “PFT be limited to tests that are only essential for immediate treatment decisions” and that “personal protective equipment...
Annals of Allergy, Asthma & Immunology
Tue May 26, 2020 03:00
Diagnosis of Peanut Allergy Using Continuous Likelihood Ratios
Peanut allergy (PA) is associated with an economic and psychologic burden on patients and families. Its diagnosis includes tests for peanut specific IgE (sIgE), the values of which usually are categorized as positive or negative using a predefined cutoff (usually 0.35kU/L). With the use of Bayes theorem, this categorization can be replaced with a continuous interpretation if sIgE which accounts for the prevalence of PA and history of ingestion.
Annals of Allergy, Asthma & Immunology
Mon May 25, 2020 03:00
Un Astrobiólogo en la Corte del Coronavirus (entrevista a César Menor-Salván)
César Menor-SalvánEl genial Mark Twain hizo viajar a un Yankee a la Corte del Rey Arturo, un viaje fantástico ya no solo por el desafío a la flecha del tiempo que supone viajar al pasado sino también por el aún más grande desafío de viajar de la realidad a la leyenda. En 1979, con los hitos de la carrera espacial presentes en el imaginario popular, y el cine en su apogeo, el Director Russ Mayberry decidió hacer una adaptación cinematográfica de la novela de Twain con un Astronauta como visitante...
La nueva Ilustración Evolucionista / The new Evolutionary Enlightenment
Tue May 26, 2020 19:00
Fidget Spinner for Rapid Detection of Urinary Tract Infections
More than half of all women experience at least one episode of urinary tract infection (UTI) in their lifetime, with men also facing increasing risks of infection as they age. Current detection of UTIs rely on patients reporting symptoms followed by a lab culture of the urine for known bacterial culprits, which typically takes a few days. However, doctors tend to prescribe antibiotics to suppress any suspect cases of UTI before they get the test results, contributing to the increasing problem of...
Medgadget
Tue May 26, 2020 14:58
Smartphone Measures Hemoglobin Levels in Photos of Eyelids
Anemia is properly diagnosed using a blood test that measures hemoglobin, but simply looking behind a patient’s eyelid can be a pretty good alternative if you know how red the tissue is supposed to be. Now, a team at Purdue University has developed a technology that lets a clinician use smartphone pictures of the inner eyelid to automatically obtain surprisingly accurate results of blood hemoglobin levels. This capability is expected to soon be fully integrated into an app that will perform the necessary...
Medgadget
Tue May 26, 2020 17:48
Targeted and immune therapies among patients with metastatic renal carcinoma undergoing hemodialysis: A systemic review
Publication date: Available online 26 May 2020Source: Seminars in OncologyAuthor(s): E. Klajer, L. Garnier, M. Goujon, F. Schlurmann-Constans, B. Mery, T. Nguyen Tan Hon, G. Mouillet, F. Calcagno, A. Thiery-Vuillemin
Seminars in Oncology
Tue May 26, 2020 18:57
Current controversies in breast cancer screening
Publication date: Available online 26 May 2020Source: Seminars in OncologyAuthor(s): Laura Shepardson, Laura Dean
Seminars in Oncology
Tue May 26, 2020 18:57
Metabolic targeting can improve the efficiency of brain tumor biopsies
Publication date: Available online 25 May 2020Source: Seminars in OncologyAuthor(s): Maikal Villena Martín, Francisco José Pena Pardo, Fátima Jiménez Aragón, José María Borras Moreno, Ana María García Vicente
Seminars in Oncology
Tue May 26, 2020 18:57
Early stage triple negative breast cancer: Management and future directions
Publication date: Available online 25 May 2020Source: Seminars in OncologyAuthor(s): Lubna N. Chaudhary
Seminars in Oncology
Tue May 26, 2020 18:57
Chemical composition, surface roughness, and ceramic bond strength of additively manufactured cobalt-chromium dental alloys
Publication date: Available online 25 May 2020Source: The Journal of Prosthetic DentistryAuthor(s): Marta Revilla-León, Nadin Al-Haj Husain, Mohammed Mujtaba Methani, Mutlu Özcan
The Journal of Prosthetic Dentistry
Tue May 26, 2020 18:38
Use of extra-fine crosscut bur to produce horizontal texture in composite resin restorations
Publication date: Available online 25 May 2020Source: The Journal of Prosthetic DentistryAuthor(s): Pablo Lenin Benitez Sellan, Eduardo Bresciani
The Journal of Prosthetic Dentistry
Tue May 26, 2020 18:38
Opportunity Costs Pacifism
Abstract If the resources used to wage wars could be spent elsewhere and save more lives, does this mean that wars are unjustified? This article considers this question, which has been largely overlooked by Just War Theorists and pacifists. It focuses on whether the opportunity costs of war lead to a form of pacifism, which it calls ‘Opportunity Costs Pacifism’. The article argues that Opportunity Costs Pacifism is, at the more ideal level, compelling. It suggests that the only...
Latest Results for Law and Philosophy
Tue May 26, 2020 03:00
Enhanced Draping for Airway Procedures During the COVID-19 Pandemic
Publication date: Available online 26 May 2020Source: Journal of the American College of SurgeonsAuthor(s): Nikolaus E. Wolter, Clyde T. Matava, Blake C. Papsin, Alice Oloya, Marie-Eve Mercier, Eloisa Salonga, Evan J. Propst
Journal of the American College of Surgeons
Tue May 26, 2020 18:09

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,

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