Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16159-yOver 100 million of opioid prescriptions are issued yearly in the USA alone, but the impact of opioid use on the immune system is barely characterized. Here the authors report antiviral immune response is blunted in several types of blood cells from opioid-dependent individuals, and when healthy donor cells are exposed to morphine in a dish.
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16418-yThe DIS3L2 exonuclease degrades aberrant 7SL RNAs tagged by an oligouridine 3′-tail. Here the authors analyze DIS3L2 knockout mouse embryonic stem cells and suggest that DIS3L2-mediated quality control of 7SL RNA is important for ER-mediated translation and calcium ion homeostasis.
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16458-4Synthetic hair-like structures (cilia) controlled by an external field have been developed, especially for microfluidic applications. Here, Gu et al. make soft artificial cilia carpets with programmable magnetization patterns and utilize them to achieve pumping and locomotion in a soft robotic model.
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16439-7Due to poor specificity, the current pharmacotherapy of atherosclerosis has limited therapeutic efficacy. Here, the authors show that a macrophage-biomimetic nanomedicine effectively alleviates atherosclerosis via targeted pharmacotherapy and sequestration of proinflammatory cytokines and chemokines.
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16397-0The Legionella pneumophila Dot/Icm type IVB secretion system (T4BSS) translocates effector proteins into host cells, and the recognition of these effectors is mediated by the Dot/Icm type IV coupling protein (T4CP) complex. Here, the authors present the crystal structure of a four-subunit containing T4CP subcomplex bound to the effector protein VpdB, and identify a FxxxLxxxK binding motif that is present in a subset...
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16401-7The spin Hall angle (SHA) is a measure of the efficiency for converting a charge to a spin current is still challenging to tune in situ. Here, the authors demonstrate by introducing a ferroelectric (FE) material in a ferromagnetic/heavy metal stack the SHA can be voltage controled via the polarization of the FE layer.
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-16460-wDespite the non-flammable nature of water-based electrolytes, aqueous lithium-ion batteries still carry an explosion risk due to the sealing structure. Here the authors report a safe aqueous battery with an open configuration, utilizing highly concentrated electrolytes and Al2O3 coated anodes.
Nature Communications, Published online: 26 May 2020; doi:10.1038/s41467-020-15701-2The tau protein is theorized to spread transneuronally in Alzheimers disease, though this theory remains unproven in humans. Our simulations of epidemic-like protein spreading across human brain networks support this theory, and suggest the spreading dynamics are modified by β-amyloid
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Publication date: Available online 25 May 2020Source: Gait & PostureAuthor(s): Jae Jung Min, Soon-Sun Kwon, Ki Hyuk Sung, Kyoung Min Lee, Chin Youb Chung, Moon Seok Park
Publication date: Available online 25 May 2020Source: Gait & PostureAuthor(s): Arielle G. Fischer, Jennifer C. Erhart-Hledik, Jessica L. Asay, Constance R. Chu, Thomas P. Andriacchi
Publication date: Available online 25 May 2020Source: Gait & PostureAuthor(s): Megumi Ota, Hiroshige Tateuchi, Takaya Hashiguchi, Takehiro Kato, Yasuhiro Ogino, Momoko Yamagata, Noriaki Ichihashi
Publication date: Available online 25 May 2020Source: Gait & PostureAuthor(s): Sam Augsburger, Hank White, Henry Iwinski
Publication date: Available online 25 May 2020Source: Gait & PostureAuthor(s): Bernard X.W. Liew, David Rugamer, Deepa Abichandani, Alessandro Marco De Nunzio
Publication date: Available online 25 May 2020Source: Gait & PostureAuthor(s): Rina M. Magnani, Sjoerd M. Bruijn, Jaap H. van Dieën, Marcus F. Vieira
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Publication date: Available online 25 May 2020Source: Magnetic Resonance ImagingAuthor(s): Chengyan Wang, Yuan Wu, Yiping P. Du
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Publication date: Available online 26 May 2020Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Radosław Mlak, Tomasz Powrózek, Anna Brzozowska, Iwona Homa-Mlak, Marcin Mazurek, Paweł Gołębiowski, Dorota Korzeb, Mansur Rahnama-Hezavah, Teresa Małecka-Massalska
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Publication date: Available online 25 May 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Miltiadis Matsagkas, George Kouvelos
Tue May 26, 2020 19:12
Publication date: Available online 25 May 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Christian-Alexander Behrendt, Eike S. Debus
Tue May 26, 2020 19:12
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The 2020 Members of Proficiency Standards for Pulmonary Function Testing Committee of the American Thoracic Society recently raised concerns on pulmonary function testing (PFT) “as a potential avenue for COVID 19 transmission due to the congregation of patients with lung disease and because of the potential for coughing and droplet formation”. (1) The Committee reccommen-ded that “PFT be limited to tests that are only essential for immediate treatment decisions” and that “personal protective equipment...
Peanut allergy (PA) is associated with an economic and psychologic burden on patients and families. Its diagnosis includes tests for peanut specific IgE (sIgE), the values of which usually are categorized as positive or negative using a predefined cutoff (usually 0.35kU/L). With the use of Bayes theorem, this categorization can be replaced with a continuous interpretation if sIgE which accounts for the prevalence of PA and history of ingestion.
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César Menor-SalvánEl genial Mark Twain hizo viajar a un Yankee a la Corte del Rey Arturo, un viaje fantástico ya no solo por el desafío a la flecha del tiempo que supone viajar al pasado sino también por el aún más grande desafío de viajar de la realidad a la leyenda. En 1979, con los hitos de la carrera espacial presentes en el imaginario popular, y el cine en su apogeo, el Director Russ Mayberry decidió hacer una adaptación cinematográfica de la novela de Twain con un Astronauta como visitante...
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More than half of all women experience at least one episode of urinary tract infection (UTI) in their lifetime, with men also facing increasing risks of infection as they age. Current detection of UTIs rely on patients reporting symptoms followed by a lab culture of the urine for known bacterial culprits, which typically takes a few days. However, doctors tend to prescribe antibiotics to suppress any suspect cases of UTI before they get the test results, contributing to the increasing problem of...
Anemia is properly diagnosed using a blood test that measures hemoglobin, but simply looking behind a patient’s eyelid can be a pretty good alternative if you know how red the tissue is supposed to be. Now, a team at Purdue University has developed a technology that lets a clinician use smartphone pictures of the inner eyelid to automatically obtain surprisingly accurate results of blood hemoglobin levels. This capability is expected to soon be fully integrated into an app that will perform the necessary...
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Publication date: Available online 26 May 2020Source: Seminars in OncologyAuthor(s): E. Klajer, L. Garnier, M. Goujon, F. Schlurmann-Constans, B. Mery, T. Nguyen Tan Hon, G. Mouillet, F. Calcagno, A. Thiery-Vuillemin
Publication date: Available online 26 May 2020Source: Seminars in OncologyAuthor(s): Laura Shepardson, Laura Dean
Publication date: Available online 25 May 2020Source: Seminars in OncologyAuthor(s): Maikal Villena Martín, Francisco José Pena Pardo, Fátima Jiménez Aragón, José María Borras Moreno, Ana María García Vicente
Publication date: Available online 25 May 2020Source: Seminars in OncologyAuthor(s): Lubna N. Chaudhary
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Publication date: Available online 25 May 2020Source: The Journal of Prosthetic DentistryAuthor(s): Marta Revilla-León, Nadin Al-Haj Husain, Mohammed Mujtaba Methani, Mutlu Özcan
Publication date: Available online 25 May 2020Source: The Journal of Prosthetic DentistryAuthor(s): Pablo Lenin Benitez Sellan, Eduardo Bresciani
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Abstract If the resources used to wage wars could be spent elsewhere and save more lives, does this mean that wars are unjustified? This article considers this question, which has been largely overlooked by Just War Theorists and pacifists. It focuses on whether the opportunity costs of war lead to a form of pacifism, which it calls ‘Opportunity Costs Pacifism’. The article argues that Opportunity Costs Pacifism is, at the more ideal level, compelling. It suggests that the only...
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Publication date: Available online 26 May 2020Source: Journal of the American College of SurgeonsAuthor(s): Nikolaus E. Wolter, Clyde T. Matava, Blake C. Papsin, Alice Oloya, Marie-Eve Mercier, Eloisa Salonga, Evan J. Propst
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,