Cross-lineage protection by human antibodies binding the influenza B hemagglutinin

Cross-lineage protection by human antibodies binding the influenza B hemagglutinin

Cross-lineage protection by human antibodies binding the influenza B hemagglutinin, Published online: 18 January 2019; doi:10.1038/s41467-018-08165-y

Immune recognition of Influenza B virus (IBV) is poorly understood. Here, Liu et al. use flow cytometry to characterize IBV-specific memory B cell responses following seasonal vaccination and show that elicited cross-reactive antibodies can protect against infection, providing a platform for vaccine design.

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