Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Low-frequency variation in <i>TP53</i> has large effects on head circumference and intracranial volume, Published online: 21 January 2019; doi:10.1038/s41467-018-07863-x

Size and shape of the brain are, among others, influenced by the dimensions of the skull. Here, the authors report genome-wide association studies for head circumference and intracranial volume in children and adults and the identification of nine common or low-frequency variants associated with these traits.

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