Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects

Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects

Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects, Published online: 21 January 2019; doi:10.1038/s41467-018-08000-4

Obesity and the distribution of fat within the body are risk factors for cardiometabolic diseases. Here, Rask-Andersen et al. perform GWAS for bio-electrical impedance measurements in UK Biobank participants and identify 29 novel independent loci for fat distribution and a high degree of sex-heterogeneity.

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