Related ArticlesIntussusceptive Vascular Remodeling Precedes Pathological Neovascularization. Arterioscler Thromb Vasc Biol. 2019 Jul;39(7):1402-1418 Authors: Ali Z, Mukwaya A, Biesemeier A, Ntzouni M, Ramsköld D, Giatrellis S, Mammadzada P, Cao R, Lennikov A, Marass M, Gerri C, Hildesjö C, Taylor M, Deng Q, Peebo B, Del Peso L, Kvanta A, Sandberg R, Schraermeyer U, Andre H, Steffensen JF, Lagali N, Cao Y, Kele J, Jensen LD Abstract Objective- Pathological...
Related ArticlesA real-world study of socioeconomic factors with survival in adults aged 18-64 years with renal cell carcinoma. Future Oncol. 2019 Jun 26;: Authors: Zhang SL, Zhang ZY, Liu ZJ, Wang WR, Li ZM, Han B, Wang X, Wang LS Abstract Aim: To evaluate the impact of socioeconomic factors (SEFs) on survival of renal cell carcinoma (RCC) patients. Materials & methods: RCC patients diagnosed between 2007 and 2015 were collected from the SEER database....
Related ArticlesSystematic Review of adverse events reporting in clinical trials leading to approval of targeted therapy and immunotherapy. Future Oncol. 2019 Jun 26;: Authors: Bossi P, Botta L, Bironzo P, Sonetto C, Musettini G, Sbrana A, Di Giannantonio V, Locati LD, Di Maio M, Antonuzzo A Abstract Aim: Reporting toxicities of targeted therapies (TTs) and immunotherapy in oncology requires special attention. Materials & methods: We identified TTs...
Related ArticlesRadiomics: an Introductory Guide to What It May Foretell. Curr Oncol Rep. 2019 Jun 25;21(8):70 Authors: Nougaret S, Tibermacine H, Tardieu M, Sala E Abstract PURPOSE OF REVIEW: To briefly review the radiomics concept, its applications, and challenges in oncology in the era of precision medicine. RECENT FINDINGS: Over the last 5 years, more than 500 studies have evaluated the role of radiomics to predict tumor diagnosis, genetic...
Related ArticlesDuality of purpose: Participant and parent understanding of the purpose of genomic tumor profiling research among children and young adults with solid tumors. JCO Precis Oncol. 2019;3: Authors: Marron JM, Cronin AM, DuBois SG, Glade-Bender J, Kim A, Crompton BD, Meyer SC, Janeway KA, Mack JW Abstract PURPOSE: Increasing use of genomic tumor profiling may blur the line between research and clinical care. We aimed to describe research participants'...
Related ArticlesDevelopment of an Empirically Calibrated Model of Esophageal Squamous Cell Carcinoma in High-Risk Regions. Biomed Res Int. 2019;2019:2741598 Authors: Wang Z, Zhang Q, Wu B Abstract Objective: This study constructs, calibrates, and verifies a mathematical simulation model designed to project the natural history of ESCC and is intended to serve as a platform for testing the benefits and cost-effectiveness of primary and secondary ESCC prevention...
Related ArticlesΓδ T Cell-Based Immunotherapy in Melanoma: State of the Art. J Oncol. 2019;2019:9014607 Authors: Toia F, Di Stefano AB, Meraviglia S, Lo Presti E, Pirrello R, Rinaldi G, Fulfaro F, Dieli F, Cordova A Abstract Metastatic melanoma is still associated with a poor prognosis, and there is increasing interest in immunotherapy alone or in combination with other adjuvant therapies. Γδ T lymphocytes play a pivot role in the immune response against...
Related ArticlesTargeting CXCL12/CXCR4 and myeloid cells to improve the therapeutic ratio in patient-derived cervical cancer models treated with radio-chemotherapy. Br J Cancer. 2019 Jun 26;: Authors: Lecavalier-Barsoum M, Chaudary N, Han K, Pintilie M, Hill RP, Milosevic M Abstract BACKGROUND: The CXCL12/CXCR4 chemokine pathway is involved in cervical cancer pathogenesis and radiation treatment (RT) response. We previously reported that radiochemotherapy...
Related ArticlesInvasive lobular breast cancer: A review of pathogenesis, diagnosis, management, and future directions of early stage disease. Semin Oncol. 2019 Jun 17;: Authors: Thomas M, Kelly ED, Abraham J, Kruse M Abstract Invasive lobular carcinoma (ILC) is the second most common type of invasive breast cancer after invasive ductal carcinoma (IDC). Invasive lobular carcinoma has unique clinical, pathologic, and radiographic features which suggest...
Related ArticlesComparative safety and efficacy of anti-PD-1 monotherapy, chemotherapy alone, and their combination therapy in advanced nasopharyngeal carcinoma: findings from recent advances in landmark trials. J Immunother Cancer. 2019 Jun 25;7(1):159 Authors: Lv JW, Li JY, Luo LN, Wang ZX, Chen YP Abstract Recent phase 1-2 trials reported manageable safety profiles and promising antitumor activities of anti-PD-1 drugs (pembrolizumab, nivolumab, camrelizumab...
Related ArticlesCause-specific death assessment of patients with stage I small-cell lung cancer: a competing risk analysis. Future Oncol. 2019 Jun 26;: Authors: Liu J, Zhou H, Zhang Y, Fang W, Yang Y, Hong S, Chen G, Zhao S, Chen X, Zhang Z, Xian W, Shen J, Huang Y, Zhao H, Zhang L Abstract Aim: Stage I small-cell lung cancer (SCLC) is a potentially curable disease that needs timely and multidisciplinary management. The aim of this study was to evaluate...
Related ArticlesUtilization of tumor genomics in clinical practice: an international survey among ASCO members. Future Oncol. 2019 Jun 26;: Authors: Barroso-Sousa R, Guo H, Srivastava P, James T, Birch W, Siu LL, Tew WP, Tolaney SM Abstract Aim: To identify patterns of use and barriers to tumor genomic testing among oncologists. Methods: We surveyed American Society of Clinical Oncology physician members about their use of genomic testing. Results: Among...
Related ArticlesThe day after De-ESCALaTE and RTOG 1016 trials results. Future Oncol. 2019 Jun 26;: Authors: Orlandi E, Licitra L PMID: 31238718 [PubMed - as supplied by publisher]
Related Articles["Watch and wait" strategy after neoadjuvant therapy for rectal cancer: status survey of perceptions, attitudes and treatment selection in Chinese surgeons]. Zhonghua Wei Chang Wai Ke Za Zhi. 2019 Jun 25;22(6):550-559 Authors: Sun TT, Wang L, Yao YF, Peng YF, Zhao J, Zhan TC, Leng JH, Wang HY, Chen N, Chen PJ, Li YJ, Zhang X, Liu XZ, Zhang Y, Wu AW Abstract Objective: To understand the perceptions, attitudes and treatment selection of...
Related ArticlesTreatment with intravenous immunoglobulin in patients with recurrent pregnancy loss: An update. J Reprod Immunol. 2019 Jun 18;133:37-42 Authors: Christiansen OB, Kolte AM, Krog MC, Nielsen HS, Egerup P Abstract Intravenous immunoglobulin (IVIg) has a documented clinical effect in many autoimmune diseases and has so far been tested in >10 randomised controlled trials (RCTs) in women with recurrent pregnancy loss (RPL). The results of...
Related ArticlesManagement of distal ureter and bladder cuff at the time of nephroureterectomy: surgical techniques and predictors of outcome. Future Oncol. 2019 Jun 25;: Authors: Attalla K, Patnaik S, Vellos T, Mehrazin R Abstract Open radical nephroureterectomy (NU) with removal of the ureter and bladder cuff is the 'gold standard' in the treatment of high-grade urothelial cancers of the upper urinary tract. A salient issue is the management of the...
Related ArticlesBladder cancer mortality after a diagnosis of nonmuscle-invasive bladder carcinoma. Future Oncol. 2019 Jun 25;: Authors: Abdel-Rahman O Abstract Aim: To assess mortality from bladder cancer following a diagnosis of nonmuscle-invasive bladder cancer. Materials & methods: This is a SEER registry-based study. The risk of death from bladder cancer was compared with that of the general population. Cox proportional model was performed to...
Related ArticlesClinical implications of mismatch repair deficiency in prostate cancer. Future Oncol. 2019 Jun 25;: Authors: Sedhom R, Antonarakis ES Abstract Immune checkpoint blockade holds great promise in the treatment of solid tumors but has not yet been approved for use in advanced prostate cancer. This is largely due to the relatively modest response in clinical trials in unselected patients and the lack of available biomarkers to predict clinical...
Related ArticlesPreoperative high c-reactive protein/albumin ratio is a poor prognostic factor of oral squamous cell carcinoma. Future Oncol. 2019 Jun 25;: Authors: Wang Q, Song X, Zhao Y, He Q, Shi M, Xu P, Ni S, Chen Y, Lin J, Zhang L Abstract Aim: To explore whether c-reactive protein/albumin (CRP/Alb) ratio is a poor prognostic factor for patients with oral squamous cell carcinoma (OSCC). Patients & methods: Receiver-operating characteristic...
Related ArticlesAnti-PD-1 versus anti-PD-L1 therapy in patients with pretreated advanced non-small-cell lung cancer: a meta-analysis. Future Oncol. 2019 Jun 25;: Authors: Tartarone A, Roviello G, Lerose R, Roudi R, Aieta M, Zoppoli P Abstract Aim: At present three immune checkpoint inhibitors (ICIs), two anti-PD-1 (nivolumab and pembrolizumab) and one anti-PD-L1 (atezolizumab) can be used in pretreated non-small-cell lung cancer patients. The aim of...
Prognostic impact of tumor-associated macrophage infiltration in esophageal cancer: a meta-analysis.
Related ArticlesPrognostic impact of tumor-associated macrophage infiltration in esophageal cancer: a meta-analysis. Future Oncol. 2019 Jun 25;: Authors: Li J, Xie Y, Wang X, Li F, Li S, Li M, Peng H, Yang L, Liu C, Pang L, Zou H, Zhao J, Qi Y, Cao Y, Hu J Abstract Aim: To provide clarity surrounding the association between tumor-associated macrophages (TAMs) and esophageal cancer prognosis. Materials & methods: Several databases were searched. The...
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Related ArticlesRadiation therapy for extrahepatic bile duct cancer: Current evidences and future perspectives. World J Clin Cases. 2019 Jun 06;7(11):1242-1252 Authors: Koo T, Park HJ, Kim K Abstract Extrahepatic bile duct cancer (EBDC) is a rare malignancy that involves neoplastic changes extending from both hepatic ducts to the common bile duct. The treatment of choice is surgical resection, but the predominant pattern of initial treatment failure...
Related ArticlesPancreatic Ductal Organoids React Kras Dependent to the Removal of Tumor Suppressive Roadblocks. Stem Cells Int. 2019;2019:2079742 Authors: Perkhofer L, Engler M, Gout J, Arnold F, Morawe M, Breunig M, Seufferlein T, Kleger A, Frappart PO Abstract Pancreatic ductal adenocarcinoma (PDAC) is still the Achilles heel in modern oncology, with an increasing incidence accompanied by a persisting high mortality. The developmental process of PDAC...
Related ArticlesVitamin D receptors (VDR), hydroxylases CYP27B1 and CYP24A1 and retinoid-related orphan receptors (ROR) level in human uveal tract and ocular melanoma with different melanization levels. Sci Rep. 2019 Jun 24;9(1):9142 Authors: Markiewicz A, Brożyna AA, Podgórska E, Elas M, Urbańska K, Jetten AM, Slominski AT, Jóźwicki W, Orłowska-Heitzman J, Dyduch G, Romanowska-Dixon B Abstract In recent years, a significant number of studies have investigated...
Related ArticlesAchieving a timely diagnosis for teenagers and young adults with cancer: the ACE "too young to get cancer?" study. BMC Cancer. 2019 Jun 24;19(1):616 Authors: Dommett RM, Pring H, Cargill J, Beynon P, Cameron A, Cox R, Nechowska A, Wint A, Stevens MCG Abstract BACKGROUND: Time to diagnosis (TTD) concerns teenagers and young adults (TYA) with cancer and may affect outcome. METHODS: Healthcare records from 105 TYA in a regional...
Related ArticlesRamucirumab and paclitaxel in patients with gastric cancer and prior trastuzumab: subgroup analysis from RAINBOW study. Future Oncol. 2019 Jun 25;: Authors: De Vita F, Borg C, Farina G, Geva R, Carton I, Cuku H, Wei R, Muro K Abstract Aim: This subgroup analysis of the RAINBOW study evaluated the efficacy and safety of ramucirumab in patients with gastric cancer/gastroesophageal junction adenocarcinoma who received prior trastuzumab therapy....
Related ArticlesLung Transplantation in Hungary From Cardiac Surgeons' Perspective. Transplant Proc. 2019 May;51(4):1263-1267 Authors: Fazekas L, Ghimessy Á, Gieszer B, Radeczky P, Mészáros L, Török K, Bogyó L, Hartyánszky I, Pólos M, Daróczi L, Agócs L, Kocsis Á, Bartók T, Dancs T, Tóth KK, Schönauer N, Madurka I, Elek J, Döme B, Rényi-Vámos F, Lang G, Farkas A Abstract Thoracic organ transplantation made a fresh start in Hungary with the first double...
Related Articles[Fudan experience of neoadjuvant treatment for rectal cancer]. Zhonghua Wei Chang Wai Ke Za Zhi. 2019 Apr 25;22(4):336-341 Authors: Zhang J, Shen LJ, Wan JF, Yang LF, Zhu J, Zhang Z Abstract Neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. Fudan University Shanghai Cancer Center has carried out multiple series of studies to explore the optimization of the neoadjuvant therapy since 2005. On the...
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Related ArticlesHolistic services for people with advanced disease and chronic or refractory breathlessness: a mixed-methods evidence synthesis Book. 2019 6 Authors: Maddocks M, Brighton LJ, Farquhar M, Booth S, Miller S, Klass L, Tunnard I, Yi D, Gao W, Bajwah S, Man WDC, Higginson IJ Abstract BACKGROUND: Breathlessness is a common and distressing symptom of many advanced diseases, affecting around 2 million people in the UK. Breathlessness increases with disease progression...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,