Diffuse Skeletal Hemangiomatosis Mimicking Metastastic Disease on 18F-FDG PET/CT

Diffuse skeletal hemangiomatosis is a rare vascular proliferation disorder involving multiple bones and may be confused with metastatic bone malignancy. We present a case of a 53-year-old man suffering back and proximal right femur pain underwent 18F-FDG PET/CT scan. Multiple hypermetabolic lesions of bone were concerning for metastatic carcinoma. Since no primary malignancy was found, open biopsy was performed and histologic examination led to a diagnosis of diffuse skeletal angiomatosis. This case highlighted the importance of including diffuse skeletal hemangiomatosis in the differential diagnosis of multiple hypermetabolic skeletal lesions on 18F-FDG PET/CT. Received for publication August 30, 2018; revision accepted November 16, 2018. Yunxia Ye and Wenjie Zhang contributed equally to this work and shared joint first authorship. Conflicts of interest and sources of funding: none declared. Correspondence to: Xiaohong Ou, MD, Department of Nuclear Medicine, West China Hospital, Sichuan University, No.37, Guoxue, Alley, Chengdu 610041, People's Republic of China. E-mail: xiaohong_ou@163.com. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.

from A via a.sfakia on Inoreader http://bit.ly/2AELTt0