Childhood Health and Educational Outcomes Associated with Maternal Sleep Apnea: A Population Record-Linkage Study.

Childhood Health and Educational Outcomes Associated with Maternal Sleep Apnea: A Population Record-Linkage Study.

Sleep. 2017 Oct 05;:

Authors: Bin YS, Cistulli PA, Roberts CL, Ford JB

Abstract
Objectives: Sleep apnea in pregnancy is known to adversely affect birth outcomes. Whether in utero exposure to maternal sleep apnea is associated with long-term childhood consequences is unclear.
Methods: Population-based longitudinal study of singleton infants born during 2002 to 2012 was conducted using linked birth, hospital, death, developmental, and educational records from New South Wales, Australia. Maternal sleep apnea during pregnancy was identified from hospital records. Outcomes were mortality and hospitalisations up to age 6, developmental vulnerability in the 1st year of school (aged 5-6), and performance on standardised tests in the 3rd year of school (aged 7-9). Cox proportional hazards and modified Poisson regression models were used to calculate hazard and risk ratios for outcomes in children exposed to maternal apnea compared to those not exposed.
Results: 209 of 626,188 singleton infants were exposed to maternal sleep apnea. Maternal apnea was not significantly associated with mortality (Fisher's exact p=0.48), developmental vulnerability (adjusted RR 1.29; 95% CI 0.75-2.21), special needs status (1.58; 0.61-4.07), or low numeracy test scores (1.03; 0.63-1.67) but was associated with low reading test scores (1.55; 1.08-2.23). Maternal apnea significantly increased hospitalisations in the 1st year of life (adjusted HR 1.81; 95% CI 1.40-2.34) and between the 1st and 6th birthdays (1.41; 1.14-1.75). This is partly due to admissions for suspected paediatric sleep apnea.
Conclusions: Maternal sleep apnea during pregnancy is associated with poorer childhood health. Its impact on developmental and cognitive outcomes warrants further investigation.

PMID: 29029347 [PubMed - as supplied by publisher]

from # All Medicine by Alexandros G. Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2wZ1sYX
via IFTTT