Clinical and pathological analyses of tuberculosis in the oral cavity: report of 11 cases

Publication date: Available online 28 September 2017
Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Author(s): Wu-tong Ju, Yong Fu, Ying Liu, Yi-ran Tan, Min-jun Dong, Li-zhen Wang, Jiang Li, Lai-ping Zhong
ObjectiveTo analyze tuberculosis (TB) in the oral cavity according to clinical appearance, clinical differential diagnosis, treatment, and outcome.Study DesignWe enrolled 11 patients with TB in the oral cavity between November 2012 and November 2016. Glossal lymphoid TB was excluded. Clinical symptoms, auxiliary examinations, treatments, and outcomes were recorded and analyzed.ResultsThere were six men and five women, with a mean age of 59 years. Five patients presented with ulcer, five with a mass, and one with osteomyelitis. Excisional biopsy was performed in three patients, mass resection in seven, and curettage of mandibular lesion in one. After pathological diagnosis of TB in the oral cavity in eight patients, six of them underwent purified protein derivative examination; four of them were positive and received drug therapy. The mean follow-up period was 24.9 months, with no recurrence.ConclusionsTB in the oral cavity is rare, with no specific clinical appearance. Pathology, acid-fast staining, PCR, or DNA test for Mycobacterium tuberculosis is useful for final diagnosis. Surgery is suggested as the treatment of choice, with good clinical outcomes.



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