Efficacy of Banxia Xiexin decoction for chronic atrophic gastritis: A systematic review and meta-analysis

als.fakia shared this article with you from Inoreader Efficacy of Banxia Xiexin decoction for chronic atrophic gastritis: A systematic review and meta-analysis Via PLOS ONE Alerts: New Articles by Yang Cao, Yixin Zheng, Jingbin Niu, Chunmei Zhu, Decai Yang, Fen Rong, Guoping Liu Background Banxia Xiexin decoction (BXD), a classical formula of traditional Chinese medicine (TCM), has been wildly used for chronic atrophic gastritis (CAG) patients with the cold-heat complex syndrome in China, and achieved satisfied effects. However, the clinical effects of it remains unclear. Purpose The purpose of this article is to evaluate the clinical efficacy and safety of BXD for CAG treatment. Methods We searched seven electronic databases including Ovid, Embase, PubMed, Cochrane Library, Wan-fang database, VIP (Chinese Scientific Journals Database) and CNKI (China National Knowledge Infrastructure) from their inception to September 21, 2020. We used Jadad scale and Cochrane Collaboration's risk of bias tool to make evaluation of methodological quality. Revman 5.3 statistical software was used for statistical processing to evaluate the clinical efficacy and safety of BXD. Results 26 randomized controlled trials (RCTs) totaling 1985 patients were identified for analysis. Meta-analysis showed that BXD treatment was more effective (RR 1.29; 95%CI 1.24, 1.35; P Conclusions The meta-analysis showed that BXD was more effective and safer for CAG patients than the control group. However, due to limitations of methodological quality and small sample size of the included studies, further standardized research of rigorous design should be needed. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.