Magnetically Controlled Growing Rod for Early Onset Scoliosis: A Systematic Review and Meta-Analysis.

Magnetically Controlled Growing Rod for Early Onset Scoliosis: A Systematic Review and Meta-Analysis.

World Neurosurg. 2019 Feb 01;:

Authors: Tang N, Zhao H, Shen JX, Zhang JG, Li SG

Abstract
BACKGROUND: The goal of the current systematic review and meta-analysis was to explore the utilization of magnetically controlled growing rod (MCGR) for the treatment of early onset scoliosis based on eligible studies demonstrating efficacy.
METHODS: Online electronic databases were searched to identify the eligible studies updated to April 2018 according to the index words. Several literatures that were relevant to the present analysis were also included. Mean difference (MD) or relative risk (RR) along with 95% confidence interval (95% CI) was used to analyze the main outcomes.
RESULTS: Totally, 11 studies were included in the meta-analysis with 186 patients in the MCGR group and 64 patients in the conventionally growing rod (CGR) group; three studies were case-control studies, and eight studies were self-control studies. The results indicated that MCGR had significantly decreased the Cobb angle and thoracic kyphosis, and increased T1-T12 distance, and T1-S1 distance. In addition, the incidence of complications after MCGR therapy was 0.37%. However, there was no significant difference in the change of Cobb angle and the incidence of complications between the MCGR group and the CGR group.
CONCLUSION: We demonstrated that MCGR significantly reduced the Cobb angle and thoracic kyphosis while markedly increase T1-T12 distance and T1-S1 distance. However, a close comparison of MCGR with CGR reveals more high-quality RCTs with a larger sample size and long-term follow-ups are needed to gather more robust evidence on the efficacy of MCGR for early onset scoliosis.

PMID: 30716487 [PubMed - as supplied by publisher]

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