Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats

Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats

Generation of pluripotent stem cell-derived mouse kidneys in <i>Sall1</i>-targeted anephric rats, Published online: 05 February 2019; doi:10.1038/s41467-019-08394-9

The use of pluripotent-stem cell derived organs for transplantation would be promising, if organs can be grown in a suitable host. Here, the authors use interspecific blastocyst complementation to generate a mouse pluripotent stem cell-derived kidney in anephric Sall1 mutant rats.

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