Bacterial cGAS-like enzymes synthesize diverse nucleotide signals

Bacterial cGAS-like enzymes synthesize diverse nucleotide signals

Bacterial cGAS-like enzymes synthesize diverse nucleotide signals, Published online: 20 February 2019; doi:10.1038/s41586-019-0953-5

A bacterial family of cGAS/DncV-like nucleotidyltransferases synthesizes a diverse range of cyclic dinucleotide and trinucleotide compounds that are likely to modulate the interaction of both pathogens and commensal microbiota with their animal and plant hosts.

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