Malignant transformation of a non-healing traumatic wound on the lower extremity: A case report.

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Malignant transformation of a non-healing traumatic wound on the lower extremity: A case report.

Int J Surg Case Rep. 2018;53:468-470

Authors: Day DL, Chakari W, Matzen SH

Abstract
OBJECTIVE: Malignant transformation of chronic non-healing wounds is often overlooked. If a chronic wound fails to heal, or if there are changes in the characteristics of a wound, a biopsy should be performed.
METHODS: This case is presented in line with SCARE guidelines.
PRESENTATION OF CASE: We present a case of a man with a non-healing traumatic wound over two years in which a basal cell carcinoma was diagnosed by biopsy. The basal cell carcinoma was radically excised and the defect was closed using a split thickness skin transplant.
DISCUSSION: The term Marjolin's ulcer, pathophysiology and recommended treatment.
CONCLUSION: Delayed diagnosis of malignancy in chronic wounds can lead to a worsened prognosis and therefore it is important to exclude a malignant aetiology. Malignant transformation of chronic wounds is not common but Marjolin's ulcer should be considered.

PMID: 30567071 [PubMed]

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