Mucosal ‐associated invariant (MAIT) cells are deficient in systemic sclerosis

ConclusionWe demonstrate that in SSc the frequencies and absolute numbers of MAIT and γδ T cells are significantly reduced in comparison to healthy controls. MAIT and γδ T cells did not correlate with C‐reactive protein, BNP, pulmonary involvement or median skin fibrosis scale, steroid amount or disease duration. In addition, MAIT and γδ T cells decrease did not stratify with gender, interstitial lung disease or active digital ulcers. Functional studies are necessary to determine the signification of MAIT cells decrease in systemic sclerosis.This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)

from ! Medicine by Alexandros G. Sfakianakis via alwin on Inoreader http://ift.tt/2tpDHYe
via IFTTT