Patient iPSC-derived retinal organoids: Observable retinal diseases in-a-dish

xlomafota13 shared this article with you from Inoreader Patient iPSC-derived retinal organoids: Observable retinal diseases in-a-dish Via Cellular and Molecular Biology Histol Histopathol. 2021 Jan 22:18307. doi: 10.14670/HH-18-307. Online ahead of print. ABSTRACT Induced pluripotent stem cells (iPSCs), reprogrammed from human somatic cells, hold the capacity to differentiate into most human body cells. iPSCs can be differentiated into retinal organoids, a three-dimensional structured retina containing various retinal cells. Patient-specific retinal organoids provide a powerful disease model to recapitulate the disease to study the pathogenesis of inherited retinal dystrophies, to screen or discover new drugs, and most importantly to supply an unlimited cell source for retinal regeneration. PMID:33491763 | DOI:10.14670/HH-18-307 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.