Cancer immunotherapy: a promising dawn in cancer research

xlomafota13 shared this article with you from Inoreader Cancer immunotherapy: a promising dawn in cancer research Via American Journal of Blood Research Am J Blood Res. 2020 Dec 15;10(6):375-385. eCollection 2020. ABSTRACT Cancer is a highly proliferative disease, which is caused due to the loss of regulation of cell cycle and apoptosis, DNA damage, faulty repair system etc. The cancer microenvironment plays a pivotal role in disease progression as they contain different types of innate and adaptive immune cells. The most important molecules that establish a correlation between inflammation, innate immunity, adaptive immunity, and cancer are the molecules released by inflammatory cells in cancer microenvironment. These molecules secreted by the immune cells, which might activate a pro-tumorigenic and anti-tumorigenic response in cancer. In inflammatory microenvironment, the equilibrium state of immunosuppressive and immunostimulatory signals are important in tumor suppression. The immunotherapeutic approaches could be more effective in cancer treatment. However, advancement in immunobi ology and cancer are improving the prospects of immunotherapy alone and/or in combination with the conventional therapies. Thus, the review attempts to highlight a promising and futuristic immunotherapeutic approach in combination with conventional treatment modalities. PMID:33489447 | PMC:PMC7811907 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.