Ruthenium‐Catalyzed ortho C−H Borylation of Arylphosphines

Taking the stage: Phosphine‐directed ortho C−H borylation of arylphosphine derivatives was achieved using Ru catalysts. The reaction is applicable to various tertiary arylphosphine and arylphosphinite derivatives to give (o‐borylaryl)phosphorus compounds and enables easy access to functionalized phosphine ligands and ambiphilic phosphine boronate compounds, thus realizing a new late‐stage modification of phosphorus compounds.

Abstract

Efficient, phosphine‐directed ortho C−H borylation of arylphosphine derivatives was achieved using Ru catalysts for the first time. The reaction is applicable to various tertiary arylphosphine and arylphosphinite derivatives to give (o‐borylaryl)phosphorus compounds in high yields. This reaction enables easy access to a variety of functionalized phosphine ligands and ambiphilic phosphine boronate compounds, thus realizing a new late‐stage modification of phosphorus compounds.

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