Single-cell RNA-seq denoising using a deep count autoencoder

Single-cell RNA-seq denoising using a deep count autoencoder

Single-cell RNA-seq denoising using a deep count autoencoder, Published online: 23 January 2019; doi:10.1038/s41467-018-07931-2

Single-cell RNA sequencing is a powerful method to study gene expression, but noise in the data can obstruct analysis. Here the authors develop a denoising method based on a deep count autoencoder network that scales linearly with the number of cells, and therefore is compatible with large data sets.

from A via a.sfakia on Inoreader https://go.nature.com/2sKkx0p