Exploring the landscape of focal amplifications in cancer using AmpliconArchitect
Exploring the landscape of focal amplifications in cancer using AmpliconArchitect, Published online: 23 January 2019; doi:10.1038/s41467-018-08200-y
Focal amplifications are prevalent in many cancer genomes. Here, the authors present AmpliconArchitect (AA), a computational tool for reconstructing their architecture, and reveal an extrachromosomal origin for focal amplifications, including hybrid human-virus elements in HPV-mediated cancers.
from A via a.sfakia on Inoreader https://go.nature.com/2Hw0cpM
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,