Isolated giant ileal neurofibroma sans neurofibromatosis

Reetu Kundu, Sanjay Gupta, Robin Kaushik, Rajpal Singh Punia, Ravinder Kaur

Indian Journal of Cancer 2018 55(3):301-303

Neurofibromas are benign neoplasms that are usually seen in hereditary disorders such as von Recklinghausen's disease [neurofibromatosis type 1 (NF1)]. The occurrence of isolated ileal neurofibroma in patients without the classic manifestations of NF1 or multiple endocrine neoplasia (MEN) syndromes is an extremely rare entity . We report one such case of isolated ileal neurofibroma in a 60 year old woman without any other stigmata of NF. It may be the initial manifestation of NF1 or MEN 2b or malignant transformation, all of which necessitate further follow-up of these patients.

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