Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity

Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity

Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity, Published online: 28 January 2019; doi:10.1038/s41467-018-08205-7

Heterogeneity in gene expression and epigenetic states exists across individual cells. Here, the authors develop scCAT-seq, a technique for simultaneously performing ATAC-seq and RNA-seq within the same single cell.

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