Isolated fluorodeoxyglucose avid right pleural deposits/effusion on an F-18 fluorodeoxyglucose positron emission tomography/computed tomography in patients with ovarian cancer – Are they almost certainly metastatic? An extrapolation of atypical meigs' syndrome

Raja Senthil, Arun Visakh Ramachandran Nair, Thara Pratap, Chitrathara Kesavan

Indian Journal of Nuclear Medicine 2019 34(1):42-44

Majority of ovarian cancer (OC) patients are usually diagnosed at advanced stage and present with peritoneal spread/ascites. Some patients develop pleural deposits/effusion secondary to transdiaphragmatic spread of peritoneal disease/ascites. However, pleural deposits/effusion from OC in the absence of peritoneal disease/ascites are very rare. We present a case of serous carcinoma of the left ovary with fluorodeoxyglucose (FDG) avid right pleural deposits and effusion in the absence of peritoneal disease/ascites on FDG positron emission tomography (PET)/computed tomography (CT), showing excellent response to chemotherapy in subsequent PET/CT. We also discuss the pathophysiology of pleural abnormalities in patients with ovarian diseases, a characteristic disease spread pattern and recognition of which would help in the imaging interpretation.

from A via a.sfakia on Inoreader http://bit.ly/2AUjSOe