Sir William Osler once stated that "The practice of medicine is an art, based on science. Medicine is a science of uncertainty and an art of probability." While Osler's comment was made in 1893, over a century later it remains true that much variability exists in health care and that this variation in care is thought to contribute to significant waste. To some extent, this variability persists due to a perceived lack of high-quality evidence on which to base treatment decisions. This may be particularly relevant in surgery, where randomized clinical trials (RCTs), considered to provide the highest level of evidence, are difficult to perform.
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,