Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs

Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs

Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs, Published online: 20 December 2018; doi:10.1038/s41467-018-07769-8

The source of where definitive hematopoietic stem cells (dHSCs) develop in the mouse embyro has been much debated. Here, the authors identify that dHSCs arise from the intra-embyronic region by using murine embryonic explant transplantation but not from the yolk sac.

from A via a.sfakia on Inoreader https://ift.tt/2EFE3mL