Enantioselective Electrophilic Aromatic Nitration: A Chiral Auxiliary Approach

Molecular crane arms deliver nitronium ions to specific locations of concave, polyaromatic systems in a stereoselective manner. In their Communication (DOI: 10.1002/anie.201811517), S. T. Schneebeli and co‐workers now describe how the first enantioselective aromatic nitration reactions have been achieved with the help of such crane arms. These findings represent a breakthrough in terms of enabling one of the oldest reactions to finally be carried out in an enantioselective manner.

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