Stem Cell Based Tissue Regeneration of the Temporomandibular Joint

The ultimate goal of regenerative medicine is to faithfully recreate structures and organs with autogenously derived stem cells. Current technology involves creating a scaffold derived from various materials, populating it with mesenchymal stem cells harvested from fat or bone marrow, and then utilizing sophisticated cell culture techniques to coax the system to develop into a bone or organ. Progress in this area has been promising, but there are potential road blocks. When tissue is harvested and processed, the available stem cell populations may not include progenitors of the desired type.

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