Role of Toluidine Blue Staining in Suspicious Lesions of Oral Cavity and Oropharynx

AbstractOral cancer; the sixth most common malignancy in the world has one of the lowest 5  year survival rates. This can be attributed mainly to the delay in diagnosis. The purpose of this study was to evaluate the efficacy of vital staining with toluidine blue dye as an adjunct to standard clinical examination to facilitate early detection of malignant lesions of oral cavity and oropha rynx. A hospital based diagnostic test accuracy study was carried out on 55 subjects with oral mucosal disorders that included clinically suspicious premalignant or malignant lesions, in the Department of ENT, Academy of Medical Sciences, Pariyaram, Kannur, Kerala over a period of 2 years. All lesi ons were subjected to detailed clinical examination and toluidine blue staining; and dye retention was reco...

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