A review on Quinoline hydrazone derivatives as a new class of potent antitubercular and anticancer agents

Publication date: Available online 20 July 2017 Source:Beni-Suef University Journal of Basic and Applied Sciences Author(s): Mustapha C. Mandewale, Udaysinha C. Patil, Supriya V. Shedge, Uttam R. Dappadwad, Ramesh S. Yamgar Tuberculosis (TB) and Cancer remains a global public health problem in recent years. There is an urgent need for the screening of new bioactive molecules with new targets and with a different mechanism of action. Among heterocyclic compounds, compounds with Quinoline core gained much importance in medicinal chemistry. Quinoline hydrazone scaffold plays an important role in anti-tuberculosis and anticancer drug development as their derivatives have shown outstanding results. This broad spectrum of biological and biochemical activities has been further assisted by the sy...

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