microRNA ‑205 acts as a tumor suppressor and directly targets YAP1 in glioma.

microRNA‑205 acts as a tumor suppressor and directly targets YAP1 in glioma. Mol Med Rep. 2017 Jun 09;: Authors: Ji T, Zhang X, Li W Abstract Glioma is the most common form of primary malignant tumor that occurs in the central nervous system. The underlying molecular mechanism of the carcinogenesis and progression of glioma remains to be elucidated. It is well‑established that microRNAs (miRs) are associated with the regulation of glioma initiation and progression, and may represent a novel effective therapeutic strategy for the treatment of glioma. In the present study, the expression, roles and molecular mechanisms of miR‑205 in glioma were investigated. The expression levels of miR‑205 in glioma tissues, normal brain tissues, human glioma and normal HEB glia...

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