New perspectives on the roles of circular RNAs in osteoarthritis development and progression (Review)

xlomafota13 shared this article with you from Inoreader New perspectives on the roles of circular RNAs in osteoarthritis development and progression (Review) Via Experimental and therapeutic medicine Exp Ther Med. 2021 Dec;22(6):1471. doi: 10.3892/etm.2021.10906. Epub 2021 Oct 21. ABSTRACT Osteoarthritis (OA) is a common disease of the elderly, posing a major personal and socioeconomic burden. OA is characterized by painful degeneration of articular cartilage, and its prevention, diagnosis and treatment remain problematic. Circular RNAs (circRNAs) constitute a large family of non-coding RNAs that are widely distributed, stable, conserved and tissue-specific. circRNAs have been found to be closely associated with OA development and progression, and they may serve as targets for disease prevention and treatment. The aim of the present article was to review the roles of circRNAs in OA and discuss possible treatment strategies. PMID:34737811 | PMC:PMC8561767 | DOI:10.3892/etm.2021.10906 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.