Neck Dissection in Salvage Surgery for Larynx Cancer: National Cancer Database Review

xlomafota13 shared this article with you from Inoreader Neck Dissection in Salvage Surgery for Larynx Cancer: National Cancer Database Review Via otol rhinol Ann Otol Rhinol Laryngol. 2021 Jun 10:34894211024062. doi: 10.1177/00034894211024062. Online ahead of print. ABSTRACT OBJECTIVE: Salvage laryngeal surgery is the preferred treatment after failure of non-surgical treatment of larynx cancer. This study aims to identify the impact of ND in salvage surgery on survival and factors predictive of nodal metastasis. METHODS: The National Cancer Database was used to identify patients who received salvage laryngeal surgery. Demog raphics, disease characteristics, and survival were compared between the subgroups of patients stratified according to performance of ND and presence of nodal metastasis. RESULTS: Sixty-two percent of patients underwent ND. A total of 26% of patients undergoing ND had nodal metastasis. Younger age and lesser time since radiation were associated with nodal metastasis. While undergoing ND did not significantly affect survival, those with nodal metastasis had poorer survival (P = .001). CONCLUSIONS: Although ND did not show a survival benefit, younger patients and those who have had a shorter time elapsed between the start of radiation and salvage surgery may benefit from the prognostic data provided by ND. Nonetheless, the risks and benefits of elective ND in salvage larynx cancer treatment should be evaluated on an individual case basis as the data do not support a broadly applicable recommendation. PMID:34111981 | DOI:10.1177/00034894211024062 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.