Anaplastic thyroid carcinoma: Updates on WHO classification, clinicopathological features and staging.

xlomafota13 shared this article with you from Inoreader Anaplastic thyroid carcinoma: Updates on WHO classification, clinicopathological features and staging. Via Cellular and Molecular Biology Related Articles Anaplastic thyroid carcinoma: Updates on WHO classification, clinicopathological features and staging. Histol Histopathol. 2020 Nov 10;:18277 Authors: Abe I, Lam AK Abstract Anaplastic thyroid carcinoma is an uncommon carcinoma representing 1 to 4 % of all thyroid cancers. The carcinoma is most common in females of the eight decades. It is a locally advanced cancer with frequent infiltration of surrounding organs, blood vessels and skin of neck. Paraneoplastic manifestations could occur. Approximately half of the patients with anaplastic thyroid carcinoma had distant metastasis with lung and brain as the most frequent sites of metastasis. The median survival of patients with anaplastic thyroid carcinoma reported was from 1 to 6 months. The current terminology of the cancer in World Health Organization is "anaplastic thyroid carcinoma" rather than "undifferentiated thyroid carcinoma". In the latest American Joint Committee on Cancer (AJCC) TNM staging system for anaplastic thyroid carcinoma, there are updates on T and N categories. To conclude, updated knowledge of clinicopathological features, classification, pathological staging will improve our understanding of the cancer and will help in the management of the patients with this aggressive cancer. PMID: 33170501 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.