Cancer,Mixed‐phenotype acute leukemia: A cohort and consensus research strategy from the Children's Oncology Group Acute Leukemia of Ambiguous Lineage Task ForceBackground Optimal chemotherapy for treating mixed‐phenotype acute leukemia (MPAL) and the role of hematopoietic stem cell transplantation (HSCT) remain uncertain. Major limitations in interpreting available data are MPAL's rarity and the use of definitions other than the currently widely accepted criteria: the World Health Organization...
09:25
Prenatal air pollution exposure linked to infants' decreased heart rate response to stressA mother's exposure to particulate air pollution during pregnancy is associated with reduced cardiac response to stress in six-month-old infants, according to Mount Sinai research published in Environmental Health Perspectives in October. This study is the first to find that particulate air pollution exposure in utero can affect heart rate variability, which is a known risk factor for health issues.Medical Xpress...
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Plants, Vol. 8, Pages 462: Effect of Oxygen Plasma on Sprout and Root Growth, Surface Morphology and Yield of GarlicPlants, Vol. 8, Pages 462: Effect of Oxygen Plasma on Sprout and Root Growth, Surface Morphology and Yield of Garlic Plants doi: 10.3390/plants8110462 Authors: Matej Holc Gregor Primc Jernej Iskra Primož Titan Janez Kovač Miran Mozetič Ita Junkar Depending on the climate, garlic can be planted either in the fall or spring for a harvest in the summer, but spring planting might require...
09:17
Otology & Neurotology - Published Ahead-of-Print, The Management of Tympanic Membrane Perforation...
Otology & Neurotology - Published Ahead-of-Print,The Management of Tympanic Membrane Perforation With Endoscopic Type I TympanoplastyObjective: The objective of this study is to describe what we consider to be the state-of-the-art procedure for the treatment of tympanic membrane perforations, and to present the results attained in our institution. Study Design: A retrospective cohort study, using data of Verona University Hospital, Italy. This medical record includes the data of 98 patients...
09:16
Hindawi Publishing Corporation,Optical Coherence Tomography May Help Distinguish Glaucoma from Suprasellar Tumor-Associated Optic DiscPurpose. This study aimed to differentiate patients with bilateral disc cupping associated with suprasellar tumor from patients with open-angle glaucoma by analyzing differences in optical coherence tomography (OCT) of the optic nerve. Methods. In this retrospective cross-sectional study, we collected data from the eyes of 25 patients with suprasellar craniopharyngioma...
09:14
International Journal of Cancer,Vitamin D Binding Protein and Risk of Renal Cell Carcinoma in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO)Our group has conducted two previous studies on the association between vitamin D binding protein (DBP) and renal cell carcinoma (RCC), the most common form of kidney cancer, finding strong inverse associations. We undertook the current analysis to replicate our findings in a different study population that included women and non‐smokers....
09:13
eCAM Evidence-Based Complementary and Alternative Medicine IF=2,064 , Evaluation of the Bioactivities of Rumex crispus L. Leaves and Root Extracts Using Toxicity, Antimicrobial, and Antiparasitic AssaysTraditional folks in different parts of the world use Rumex crispus L. for the treatment of microbial infections, malaria, and sleeping sickness in the form of decoction or tincture. In the search for a natural alternative remedy, this study aimed to evaluate the antimicrobial, antitrypanosomal, and...
09:10
Opioid-related gifts from pharma companies linked to physician prescribing by specialtyPhysicians who received gifts from pharmaceutical companies related to opioid medications were more likely to prescribe opioids to their patients the following year, compared to physicians who did not receive such gifts, according to a new analysis led by health policy scientists at the University of Pittsburgh Graduate School of Public Health.Medical Xpress - latest medical and health news stories09:06Mark above...
09:09
Clinical Otolaryngology,Subclinical vestibular deficit in six‐canal video Head Impulse Testing (vHIT) in patients with vestibular schwannomasAbstract This is the first study to demonstrate vestibular deficit in patients with vestibular schwannoma who do not have clinical symptoms of imbalance. Balance can have significant impact on patient's quality of life, and vHIT can potentially identify those at risk of balance problems. vHIT is the only validated test for six‐canal vestibular function. vHIT...
09:08
A Study to Test Different Doses of BI 891065 Alone and in Combination With BI 754091 in Asian Patients With Different Types of Advanced Cancer (Solid Tumours)Condition: Neoplasm Interventions: Drug: BI 891065; Drug: BI 754091 Sponsor: Boehringer Ingelheim Not yet recruiting (Source: ClinicalTrials.gov)MedWorm Cancer & Oncology Clinical TrialsFri Oct 25, 2019 18:00Phase II Trial of Focal Cryotherapy for Prostate CancerCondition: Prostate Cancer Intervention: Device: Focal Cryotherapy...
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Are BI-RADS 3 findings tracked effectively?More than a quarter of women who have breast lesions categorized as BI-RADS...Read more on AuntMinnie.comRelated Reading: DBT decreases the need for short-term follow-up CEUS helps reduce unnecessary breast biopsies Elastography methods reduce unnecessary breast biopsies AI may help reduce overdiagnosis of breast cancer ARRS: Is follow-up breast MRI OK for BI-RADS 3 cases? (Source: AuntMinnie.com Headlines)MedWorm: Cancer & OncologyTue Oct 29, 2019 14:18Merck...
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The ROS-KRAS-Nrf2 axis in the control of the redox homeostasis and the intersection with survival-apoptosis pathways: Implications for photodynamic therapyPublication date: Available online 28 October 2019Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Annalisa Ferino, Valentina Rapozzi, Luigi E. XodoAbstractIn highly proliferating cancer cells oncogenic mutations reprogram the metabolism and increase the production of reactive oxygen species (ROS). Cancer cells prevent ROS...
09:05
Disseminated mucormycosis with cerebellum involvement due to Rhizomucor pusillus in a patient with multiple myeloma and secondary myelodysplastic syndrome: A case report.Authors: Chen Q, Chen K, Qian S, Wu S, Xu L, Huang X, Shi P, Wang K, Wang M, Wang X Abstract Mucormycosis is an angioinvasive fungal infection with a high mortality rate. Patients with hematological malignancies following voriconazole therapy are at high risk from mucormycosis. Here, the present study reports on a 68-year-old man...
09:04
Definition of a Good Death, Attitudes Toward Death, and Feelings of Interconnectedness Among People Taking Care of Terminally ill Patients With Cancer: An Exploratory Study.Authors: Bovero A, Gottardo F, Botto R, Tosi C, Selvatico M, Torta R Abstract The concept of a good death is crucial in palliative care, but its relationship with attitudes toward death and feelings of interconnectedness needs to be further deepened. The first aim of this study was to explore the concept of good death, attitudes...
09:04
Prognostic impact of the Controlling Nutritional Status score in patients with non-small cell lung cancer treated with pembrolizumab.Conclusions: The CONUT score has potential application as a predictor of the therapeutic effect and the prognosis of NSCLC patients treated with pembrolizumab. Our findings suggest that in addition to the programmed cell death ligand 1 expression level, the CONUT may also be a useful indicator for selecting NSCLC patients who may benefit from ICI treatment. PMID: 31656648...
09:03
Peanut-allergy therapy 'protection not a cure'Immunotherapy works by suppressing the allergic response, rather than curing it, a study suggests. (Source: BBC News | Health | UK Edition)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.MedWorm Allergy & Immunology Top 2002:26California Tightens Scrutiny of Medical Vaccine Exemptions California Tightens Scrutiny of Medical Vaccine ExemptionsA new state law...
09:02
Applied Sciences, Vol. 9, Pages 4605: A Plant-Based Artificial Haemagglutinin (A/H5N1) Strongly Induced Neutralizing Immune Responses in MiceApplied Sciences, Vol. 9, Pages 4605: A Plant-Based Artificial Haemagglutinin (A/H5N1) Strongly Induced Neutralizing Immune Responses in Mice Applied Sciences doi: 10.3390/app9214605 Authors: Pham Ho Phan Le Pham Conrad Vu Hoang Chu Developing new vaccine candidates is considered the best strategy for protecting poultry against artificial haemagglutinin (A/H5N1)...
09:02
Biology, Vol. 8, Pages 82: Autophagy in Cancer Cell Death: Biology, Vol. 8, Pages 82: Autophagy in Cancer Cell DeathBiology doi: 10.3390/biology8040082Authors: Linder Kögel Autophagy has important functions in maintaining energy metabolism under conditions of starvation and to alleviate stress by removal of damaged and potentially harmful cellular components. Therefore, autophagy represents a pro-survival stress response in the majority of cases. However, the role of autophagy in cell survival...
09:01
Remote Sensing, Vol. 11, Pages 2544: Suppressing Paired Echoes Caused by Stair-Step Antenna Steering in TOPS SAR ImagingRemote Sensing, Vol. 11, Pages 2544: Suppressing Paired Echoes Caused by Stair-Step Antenna Steering in TOPS SAR Imaging Remote Sensing doi: 10.3390/rs11212544 Authors: He Zhang Yi Jin Dong The use of electronically steered antennas in the azimuth dimension typically leads to a staircase-like antenna beam steering law in the Terrain Observation by Progressive Scan (TOPS) wide-swath...
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IJMS, Vol. 20, Pages 5396: A Novel Claudinopathy Based on Claudin-10 MutationsIJMS, Vol. 20, Pages 5396: A Novel Claudinopathy Based on Claudin-10 Mutations International Journal of Molecular Sciences doi: 10.3390/ijms20215396 Authors: Susanne Milatz Claudins are key components of the tight junction, sealing the paracellular cleft or composing size-, charge- and water-selective paracellular channels. Claudin-10 occurs in two major isoforms, claudin-10a and claudin-10b, which constitute paracellular...
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Agronomy, Vol. 9, Pages 694: Analysis of Factors Affecting the Rearing of Early-Weaned Lambs of Dairy Breeds for the Meat MarketAgronomy, Vol. 9, Pages 694: Analysis of Factors Affecting the Rearing of Early-Weaned Lambs of Dairy Breeds for the Meat Market Agronomy doi: 10.3390/agronomy9110694 Authors: Jesús P. Val-Aguasca Pablo Martín-Ramos Esperanza Horcas Jesús Yániz F. Javier García-Ramos Sheep farming makes an important socio-economic contribution to Spain's rural areas by sustaining farming...
08:59
3DPrint.com,Effect of Newly Developed (Meth)acrylate Resins on Impact Strength in 3D PrintingThe Challenge Dymax is creating solutions that allow photopolymer-based 3D printing resins to meet or exceed the capabilities of thermoplastic materials such as polycarbonate or ABS, targeting superior impact and temperature resistance properties. The goal is improvements in impact strength while maintaining a high Heat Deflection Temperature (HDT). Material Reference Product Name HR1 BR-952 HR2 Exp. Olig....
08:58
Safety Profile of Sclerosing AgentsNo abstract availableBlinded, Randomized, Controlled Trial Evaluating the Effects of Light-Emitting Diode Photomodulation on Lower Extremity Wounds Left to Heal by Secondary IntentionBACKGROUND Light-emitting diode (LED) has been used for wound healing because of its stimulatory effects on fibroblast proliferation, matrix synthesis, angiogenesis, and downmodulation of inflammatory reactions. OBJECTIVE The aim of the authors' study was to investigate the effects...
08:55
Missed Study Visits and Subsequent HIV Incidence Among Women in a Predominantly Sex Worker Cohort Attending a Dedicated Clinic Service in Kampala, UgandaBackground: There is limited evidence on the relationship between sustained exposure of female sex workers (FSWs) to targeted HIV programmes and HIV incidence. We investigate the relationship between the number of missed study visits (MSVs) within each episode of 2 consecutively attended visits (MSVs) and subsequent HIV risk in a predominantly FSW...
08:55
What Are Our Opportunities in Preparing the Next Generation of Nurses and Where Are We Going Wrong?No abstract availableLeveraging the Power of Board Leadership in Professional Nursing OrganizationsNurses who aspire to lead a professional nursing organization can significantly influence the future of the nursing profession. This article describes 4 essential responsibilities required in a board leadership position as identified by a group of nurse leaders who have each served as the board president...
08:54
Comparison of drug-eluting balloon with repeat drug-eluting stent for recurrent drug-eluting stent in-stent restenosisObjective Approximately, 10–20% of patients with drug eluting stent (DES) in-stent restenosis (ISR) will develop recurrent ISR; yet, the optimal management of recurrent DES-ISR is unknown. We sought to compare the outcomes of recurrent DES-ISR treated with drug eluting balloons (DEB) to those with repeated implantation of new-generation DES. Methods A total of 172 patients with recurrent...
08:53
An unusual case of loperamide anaphylaxisPublication date: Available online 26 October 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Adrian Y.S. Lee, Anthony J.F. Smith, Matthew Krummenacher, Tiffany L. HughesAsthma Biologics: Comparing Trial Designs, Patient Cohorts and Study ResultsPublication date: Available online 23 October 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Ali Doroudchi, Mohini Pathria, Brian D. ModenaObjectiveFive biologic therapies have FDA-approved...
08:52
Erreger, Resistenzmechanismen und etablierte Therapieoptionen bei Infektionen durch multiresistente ErregerErratum zu:Der Anaesthesist 2019https://doi.org/10.1007/s00101-019-00645-0Im ursprünglich veröffentlichten Beitrag wurden 2 Antibiotikumdosierungen in Tab. 1 falsch angegeben. Korrekt muss es in Tab. 1 „Therapieoptionen bei Infektionen durch Methicillin-resistente Staphylokokken (MRSA)" bei den …Algorithmusbasierte Präventionsstrategien zur Vermeidung neuromuskulärer RestblockadenZusammenfassungHintergrundDie...
08:52
Determination of Acrolein-Associated T 1 and T 2 Relaxation Times and Noninvasive Detection Using Nuclear Magnetic Resonance and Magnetic Resonance SpectroscopyAbstractAn estimated 3.3 million people are living with a traumatic brain injury (TBI)-associated morbidity. Currently, only invasive and sacrificial methods exist to study neurochemical alterations following TBI. Nuclear magnetic resonance methods—magnetic resonance imaging (MRI) and spectroscopy (MRS)—are powerful tools which may be used...
08:51
Ovid and Titian 2012The article Ovid and Titian 2012, written by Fiona Macintosh, was originally published electronically on the publisher's internet portal (currently SpringerLink) on 8 May 2019 without open access. With the author(s)' decision to opt for Open Choice the copyright of the article changed on 5 September 2019 to © The Author(s) 2019 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/),...
08:51
Endoscopic submucosal dissection of distal intestinal tumors using grasping forceps for tractionAbstractBackgroundThe aim of this study was to assess the efficacy of traction device-assisted endoscopic submucosal dissection (ESD) of the rectum and the distal segment of sigmoid colon using grasping forceps.MethodsA total of 43 patients scheduled for colonic ESD at our institution were enrolled between January 2013 and June 2017. The patients were randomly allocated to receive conventional ESD (group...
08:50
The effect of transcutaneous electrical nerve stimulation (TENS) on chronic subjective tinnitusAuthor links open overlay panelBelginTutara1SevgiAtarb2GülerBerkitena3OnurÜstüna4Tolgar LütfiKumrala1YavuzUyara1aDepartment of Otorhinolaryngology-Head and Neck Surgery, Okmeydani Training and Research Hospital, Darulaceze Cad. No: 25 Okmeydani - Sisli, Istanbul, TurkeybDepartment of Physical Therapy and Rehabilition, Okmeydani Training and Research Hospital, Darulaceze Cad. No: 25 Okmeydani - Sisli, Istanbul,...
08:50
Assessment of post-operative healing following endoscopic, transnasal, transsphenoidal pituitary surgery without formal sellar grafting☆Author links open overlay panelDannyJandaliaSarahShearerbRichardByrnecdPeterPapagiannopoulosaBobby A.TajudeenadPete S.BatraadaDepartment of Otorhinolaryngology – Head and Neck Surgery, Rush Medical College, Chicago, IL, United States of AmericabRush Medical College, Chicago, IL, United States of AmericacDepartment of Neurosurgery, Rush University Medical Center,...
08:49
A comment on postmortem interrogation of cardiac implantable electronic devicesCorrection to: Differentiation of endogenous and exogenous γ-Hydroxybutyrate in rat and human urine by GC/C/IRMSThe above article was published online with incorrect author names. The right spelling should be Dong-Hun Lee instead of Donghun Lee, Sanggil Choe instead of Sanggil Choi. The correct names are presented here. The original article has been corrected.Allele frequencies for 22 autosomal STRs in the Kinh population...
08:49
MR urethrography compared with operative findings for the evaluation of urethral stricturesUsefulness of retroperitoneoscopic renal needle biopsy for patients with contraindications for percutaneous renal biopsyEfficacy and safety of leflunomide in IgA nephropathy: a systematic review and meta-analysisAbstractBackgroundThe optimal therapy for immunoglobulin A nephropathy (IgAN) remains uncertain. Leflunomide (LEF) is an immunosuppressive drug which may reduce deposition of glomerular autoantibodies...
08:48
Understanding the Association Between Perceived Financial Well-Being and Life Satisfaction Among Older Adults: Does Social Capital Play a Role?The article "Understanding the Association Between Perceived Financial Well-Being and Life Satisfaction Among Older Adults: Does Social Capital Play a Role?", written by JeongHee Yeo and Yoon G. Lee, was originally published electronically on the publisher's internet portal (currently SpringerLink) on 19 June 2019 with open access.Female Earnings and the Returns...
08:48
Development of multiplex PCR to detect slow rust resistance genes Lr34 and Lr46 in wheatAbstractLeaf rust caused by Puccinia triticina belongs to one of the most dangerous fungal diseases of wheat (Triticum aestivum L.) and is the cause of large yield losses every year. Here we report a multiplex polymerase chain reaction (PCR) assay, which was developed for detection of two important wheat slow rust resistance genes Lr34 and Lr46, using two molecular markers: csLV34 and Xwmc44, respectively. The...
08:47
Sicherheitsabstand von 2 cm ist bei Exzision von Hautmelanomen dicker als 2 mm ausreichendZweitmalignomrisiko nach Behandlung von lokal begrenzten Prostatakarzinomen mit Kohlenstoffionen möglicherweise niedriger als nach PhotonenbestrahlungRadikale Prostatektomie oder „Watchful Waiting" beim frühen Prostatakarzinom?Use of psychosocial services by lung cancer survivors in GermanyAbstractPurposeLittle is known about the use of psychosocial services in lung cancer survivors and patients who have survived...
08:47
Neonatal myocardial infarction: substantial improvement of cardiac function after autologous bone marrow-derived cell therapyClinical and genetic insights into non-compaction: a meta-analysis and systematic review on 7598 individualsAbstractBackgroundLeft ventricular non-compaction has been increasingly diagnosed in recent years. However, it is still debated whether non-compaction is a pathological condition or a physiological trait. In this meta-analysis and systematic review, we compare studies,...
08:46
Diagnostic criteria should be considered when reviewing the effect of diabetes prevention studiesCorrection to: Short-term progression of cardiometabolic risk factors in relation to age at type 2 diabetes diagnosis: a longitudinal observational study of 100,606 individuals from the Swedish National Diabetes RegisterUnfortunately, the symbols in Fig. 1 were incorrectly described in the legend.Up frontCD40-targeting KGYY 15 peptides do not efficiently block the CD40–CD40L interactionDiabetes prevention...
08:46
Predicting Psychiatric Rehospitalization in AdolescentsAbstractAdolescent psychiatric rehospitalizations are common, cause patients and their families severe psychological distress, and use tremendous healthcare resources. This study sought to identify predictors of rehospitalization in 783 adolescents in the 2 year period following psychiatric hospitalization at a major treatment facility in a large urban area. A current diagnosis of posttraumatic stress disorder, greater severity of lifetime suicidal...
08:45
Robust protocol for feeder-free adaptation of cryopreserved human pluripotent stem cellsAbstractHuman pluripotent stem cells (hPSCs) are conventionally maintained on mouse embryonic fibroblast (MEF) feeder layers. However, downstream applications, such as directed differentiation protocols, are primarily optimized for feeder-free cultures. Therefore, hPSCs must often be adapted to feeder-free conditions. Here we propose a novel feeder-free adaptation protocol using StemFlex medium, which can be directly...
08:45
Molecular cloning and characterization of genes related to the ethylene signal transduction pathway in pomegranate ( Punica granatum L.) under different temperature treatmentsAbstractLow temperature storage is a common method for storing pomegranates post-harvest; however, unsuitable low temperatures can cause fruit chilling injuries, the molecular mechanism of which is as yet unclear. Ethylene is a major factor affecting the post-harvest storage quality of pomegranates, and functions mainly through...
08:44
Therapeutic observation of Tui-pushing Wujing plus Chinese patent medicine for infantile diarrhea due to spleen deficiencyAbstractObjective: To observe the therapeutic efficacy of pediatric tuina plus Chinese patent medicine for preschool kids with diarrhea due to spleen deficiency.Methods: Ninety-two eligible kids were divided into a tuina plus Chinese patent medicine and a Chinese patent medicine group by the random number table, with 46 cases in each group. The Chinese patent medicine group was...
08:44
Sitting time among adolescents across 26 Asia–Pacific countries: a population-based studyAbstractObjectivesTo assess the prevalence of sitting time (ST) and examine sex and age disparities in the prevalence among adolescents from Asia–Pacific countries.MethodsWe used the Global School-based Student Health Survey data (n = 101,785) from 26 Asia–Pacific countries and computed the pooled prevalence of high ST (≥ 3 h/day) using random effect meta-analysis. We used logistic regression to examine sex and...
08:44
Detection and measurements of apical lesions in the upper jaw by cone beam computed tomography and panoramic radiography as a function of cortical bone thicknessAbstractObjectivesIn the current literature, cone beam computed tomography (CBCT) seems to be more accurate in detecting apical lesions (AL) than two-dimensional radiographs. Cortical bone thickness might have an influence on AL visibility. Therefore, the purpose of the study was to directly compare the diagnostic accuracy of panoramic radiography...
08:43
Cortisol, oxytocin, and quality of life in major depressive disorderAbstractPurposeQuality of life (QoL) is greatly impaired in major depressive disorder (MDD). These impairments are not fully accounted for by symptom severity, may persist beyond depressive episodes, and are a risk factor for poor outcomes. MDD is often associated with prominent neuroendocrine changes and increased risk of chronic disease. However, there is a lack of research examining whether biological factors are related to QoL...
08:43
Pharmaceutical applications of 3D printing technology: current understanding and future perspectivesAbstractThree-dimensional printing (3DP) technology allows the fabrication of 3D objects with various geometrics in a layer-by-layer process. Some advantages of 3DP methods over the conventional manufacturing processes include the customization of medicines with individually adjusted doses, the ability to fabricate the sophisticated and complex solid dosage forms, on-demand manufacturing, and cost-effectiveness....
08:42
Sleep Med. 2019 Jun 8;63:142-150. doi: 10.1016/j.sleep.2019.05.016.How does music aid sleep? literature review.Dickson GT1, Schubert E2.Author information1Empirical Musicology Laboratory, University of New South Wales, Sydney, 2052, Australia. Electronic address: GaelenThomasDickson@gmail.com.2Empirical Musicology Laboratory, University of New South Wales, Sydney, 2052, Australia.AbstractWith the growth of interest in using music to treat insomnia, there is a need to collect and evaluate the literature....
Tue Oct 29, 2019 17:11
Med Educ. 2019 Oct 28. doi: 10.1111/medu.13998.Perseverance, faith and stoicism: a qualitative study of medical student perspectives on managing fatigue.Taylor TS1,2, Raynard AL2, Lingard L2.Author information1Department of Obstetrics and Gynaecology, London Health Sciences Centre, Victoria Hospital, London, Ontario, Canada.2Centre for Education Research and Innovation, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.AbstractCONTEXT:Fatigue risk management (FRM)...
Tue Oct 29, 2019 17:10
Transl Androl Urol. 2019 Sep;8(Suppl 4):S436-S441. doi: 10.21037/tau.2019.08.16.Latest advancements in ureteral stent technology.De Grazia A1,2, Somani BK3, Soria F4, Carugo D1,2, Mosayyebi A1,2.Author information1Bioengineering Science Research Group, Faculty of Engineering and the Physical Sciences, University of Southampton, Southampton, UK.2Institute for Life Sciences (IfLS), University of Southampton, Southampton, UK.3Department of Urology, University Hospital Southampton NHS Trust, Southampton,...
Tue Oct 29, 2019 17:09
Biomed Chromatogr. 2019 Oct 28:e4727. doi: 10.1002/bmc.4727.Anti-hyperuricemia activity and toxicity prediction of a novel xanthine oxidoreductase inhibitor.Zhou L1,2, Wei B2, Wu L1, Li J1, Zhu B3, Zhang L1.Author information1School of Biology and Biological Engineering, South China University of Technology, Guangzhou, P. R. China.2Evaluation and Monitoring Center of Occupational Health, Guangzhou Twelfth People's Hospital, Guangzhou, P. R. China.3Analytical and Testing Center, South China University...
Tue Oct 29, 2019 17:08
The dental anomaly: how and why dental caries and periodontitis are phenomenologically atypical.Related ArticlesThe dental anomaly: how and why dental caries and periodontitis are phenomenologically atypical. Philos Ethics Humanit Med. 2019 Oct 26;14(1):15 Authors: Rakhra D Abstract BACKGROUND: Despite their shared origins, medicine and dentistry are not always two sides of the same coin. There is a long history in medical philosophy of defining disease and various medical models have come into existence....
Tue Oct 29, 2019 17:07
Riassunto: Terns Pharmaceuticals ottiene dalla FDA la designazione di farmaco soggetto a procedura abbreviata per TERN-101, agonista del recettore FXR per il trattamento della NASHFOSTER CITY, California, e SHANGHAI--(BUSINESS WIRE)--Terns Pharmaceuticals, Inc., multinazionale biofarmaceutica dedita alla scoperta e allo sviluppo di terapie innovative per il trattamento della steatosi epatica non alcolica (non-alcoholic steatohepatitis, NASH) e del cancro, ha annunciato oggi che TERN-101, agonista...
Tue Oct 29, 2019 17:03
Five decades of urologic pathology: the accelerating expansion of knowledge in renal cell neoplasia.Related ArticlesFive decades of urologic pathology: the accelerating expansion of knowledge in renal cell neoplasia. Hum Pathol. 2019 Oct 23;: Authors: MacLennan GT, Cheng L Abstract Those who are knowledgeable in cosmology inform us that the expansion of the universe is such that the velocity at which a distant galaxy is receding from the observer is continually increasing with time. We humbly paraphrase...
Tue Oct 29, 2019 17:02
[Diagnostic value of digital breast tomosynthesis for mass lesions in dense breast].Related Articles[Diagnostic value of digital breast tomosynthesis for mass lesions in dense breast]. Zhonghua Yi Xue Za Zhi. 2019 Oct 22;99(39):3110-3113 Authors: Lü XJ, Liu N, Li Q, Li M, Zhang XL Abstract Objective: To explore the diagnostic efficiency of digital breast tomosynthesis (DBT) for mass lesions in dense breast by comparing with digital mammography (DM). Methods: A retrospective analysis was made of 125...
Tue Oct 29, 2019 17:01
CHRONOGY Eyewear Helps Regulate Body Clock with Mood LightingOsram, a German company best known for manufacturing LED lights, recently unveiled CHRONOGY Eyewear, a pair of glasses that can regulate and supplement the light that falls onto the photoreceptors in the eyes, helping to regulate our body clocks. The CHRONOGY Eyewear comes with a smartphone app that can be used to program the glasses. Intensity and timing can be set to achieve a variety of goals, whether it be to recover from jet lag faster,...
Tue Oct 29, 2019 16:59
Evidence of nuclear transport mechanisms in the protozoan parasite <em>Giardia lamblia</em>Publication date: Available online 29 October 2019Source: Biochimica et Biophysica Acta (BBA) - Molecular Cell ResearchAuthor(s): Gonzalo Federico Mayol, María Victoria Revuelta, Agostina Salusso, María Carolina Touz, Andrea Silvana RópoloAbstractNuclear-cytoplasmic trafficking of proteins is a highly regulated process that modulates multiple biological processes in eukaryotic cells. In Giardia...
Tue Oct 29, 2019 16:58
Tick-borne encephalitis virus detected in ticks in the UK for the first timeTick-borne encephalitis virus (TBEV) has been detected for the first time in ticks in the UK. The findings are part of ongoing research by Public Health England (PHE) and the Emerging and Zoonotic Infections National Institute for Health Research (NIHR) Health Protection Research Unit at the University of Liverpool.Medical Xpress - latest medical and health news stories16:31New model of irregular heartbeat could boost drug...
Tue Oct 29, 2019 16:57
Understanding and addressing social determinants to advance cancer health equity in the United States: A blueprint for practice, research, and policyAbstract Although cancer mortality rates declined in the United States in recent decades, some populations experienced little benefit from advances in cancer prevention, early detection, treatment, and survivorship care. In fact, some cancer disparities between populations of low and high socioeconomic status widened during this period. Many potentially...
Tue Oct 29, 2019 16:55
The impact of targeted cathodal transcranial direct current stimulation on reward circuitry and affect in Bipolar DisorderHealth sciences : nature.com subject feeds02:00Diagnosis of T-cell lymphoid proliferations of the skin: putting all the pieces togetherHealth sciences : nature.com subject feeds02:00Anthropometric Analysis of the Human Skull for Developmental Left-Sided Asymmetry, New FindingAbstract Background Facial and cranial asymmetry is common in bilateral vertebrates, particularly human...
Tue Oct 29, 2019 16:55
Anthropometric Analysis of the Human Skull for Developmental Left-Sided Asymmetry, New FindingAbstract Background Facial and cranial asymmetry is common in bilateral vertebrates, particularly human beings. Through years of injecting fillers and performing face-lift operation on patients, we began to observe that more fillers were required on the right side to reach symmetry and also more loose skin and soft tissue was observed on the right side in the majority of patients (Fig. 5). Here, we conducted...
Tue Oct 29, 2019 16:52
Anthropometric Analysis of the Human Skull for Developmental Left-Sided Asymmetry, New FindingAbstract Background Facial and cranial asymmetry is common in bilateral vertebrates, particularly human beings. Through years of injecting fillers and performing face-lift operation on patients, we began to observe that more fillers were required on the right side to reach symmetry and also more loose skin and soft tissue was observed on the right side in the majority of patients (Fig. 5). Here, we conducted...
Tue Oct 29, 2019 16:52
Cancers, Vol. 11, Pages 1684: NEDD9 Inhibition by miR-25-5p Activation Is Critically Involved in Co-Treatment of Melatonin- and Pterostilbene-Induced Apoptosis in Colorectal Cancer CellsCancers, Vol. 11, Pages 1684: NEDD9 Inhibition by miR-25-5p Activation Is Critically Involved in Co-Treatment of Melatonin- and Pterostilbene-Induced Apoptosis in Colorectal Cancer Cells Cancers doi: 10.3390/cancers11111684 Authors: Ji Hoon Jung Eun Ah Shin Ju-Ha Kim Deok Yong Sim Hyemin Lee Ji Eon Park Hyo-Jung Lee...
Tue Oct 29, 2019 16:51
Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cellsAbstract Cholesterol accumulation in late endosomes is a prevailing phenotype of Niemann-Pick type C1 (NPC1) mutant cells. Likewise, annexin A6 (AnxA6) overexpression induces a phenotype reminiscent of NPC1 mutant cells. Here, we demonstrate that this cellular cholesterol imbalance is due to AnxA6 promoting Rab7 inactivation via TBC1D15, a Rab7-GAP. In NPC1 mutant cells, AnxA6 depletion and eventual...
Tue Oct 29, 2019 16:50
Journal of Esthetic and Restorative Dentistry,Clinical evaluation of chairside‐fabricated partial crowns composed of zirconia‐reinforced lithium silicate ceramics: 3‐year results of a prospective practice‐based studyAbstract Objectives Prospective practice‐based clinical evaluation of chairside fabricated monolithic partial crowns composed of zirconia‐containing lithium silicate (ZLS) ceramic material. Materials and Methods Between October 2013 and September 2014, 71 patients were restored with...
Tue Oct 29, 2019 16:46
Latest Results for Thyroid Research,The surgical management of locally advanced well-differentiated thyroid carcinoma: changes over the years according to the AJCC 8th edition Cancer Staging ManualAbstract Background Well-differentiated thyroid carcinoma is defined as locally advanced in the presence of an extra thyroid extension, e.g., when the surrounding structures such as the trachea, larynx, esophagus and main blood vessels are invaded by cancer. The 8th edition AJCC Cancer Staging Manual states...
Tue Oct 29, 2019 16:44
NeuroImage,Pharmacologically informed machine learning approach for identifying pathological states of unconsciousness via resting-state fMRIPublication date: Available online 29 October 2019Source: NeuroImageAuthor(s): Justin Campbell, Zirui Huang, Jun Zhang, Xuehai Wu, Pengmin Qin, Georg Northoff, George A. Mashour, Anthony G. HudetzAbstractDetermining the level of consciousness in patients with disorders of consciousness (DOC) remains challenging. To address this challenge, resting-state fMRI...
Tue Oct 29, 2019 16:42
Trials - Correction to: Project management lessons learned from the multicentre CYCLE pilot randomized controlled trialFollowing publication of the original article [1], we have been notified that one of the authors' names is spelled incorrectly. In this Correction the incorrect and correct author name are shown.Trials - Latest Articles2dCorrection to: Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial – the development of the...
Tue Oct 29, 2019 16:41
Latest Results for European Journal of Pediatrics,Safety of tenofovir during pregnancy: early growth outcomes and hematologic side effects in HIV-exposed uninfected infantsAbstract Intrauterine exposure to zidovudine-based combination antiretroviral therapy (cART) can cause severe anemia within the first weeks of life. Tenofovir disoproxil fumarate (TDF)–based regimens may have less hematologic side effects but may affect growth parameters. This study aimed to assess the safety of TDF for prevention...
Tue Oct 29, 2019 16:40
Journal of Oral and Maxillofacial Surgery,News and AnnouncementsThe first woman in the history of the AAOMS Board of Trustees – Dr Debra M. Sacco – was elected by the House of Delegates during the 2019 AAOMS Annual Meeting in Boston, MA. The 2019-20 AAOMS Officers and Trustees are:Journal of Oral and Maxillofacial Surgery12hThe Midfacial Advancement Line - a comparative evaluation of a new measurement method in orthognathic surgeryFor planning an intraoral quadrangular Le Fort II osteotomy (IQLFIIO),...
Tue Oct 29, 2019 16:39
Milled versus moulded mock-ups based on the superimposition of 3D meshes from digital oral impressions: a comparative in vitro study in the aesthetic areaAbstract Background Aesthetic porcelain veneers proved to be a long-term reliable prosthetic solution, ensuring minimal invasiveness. The use of veneers requires an adhesive cementation technique, so maintaining as much enamel as possible is to ensure lasting success. A diagnostic mock-up is a key tool that allows a preview of the outcome of the...
Tue Oct 29, 2019 16:37
Phys.org: Cell & Microbiology News,New strategies against the antibiotics crisisOne of the most serious threats to public health worldwide is posed by antibiotic-resistant pathogens. The World Health Organization (WHO) warns of the imminent beginning of a post-antibiotic era in which harmless infections can no longer be treated and could once again become one of the most frequent non-natural causes of death. Decades of using various antibiotics as standard therapy have greatly reduced the spectrum...
Tue Oct 29, 2019 16:35
Health sciences : Letermovir prophylaxis through day 100 post transplant is safe and effective compared with alternative CMV prophylaxis strategies following adult cord blood and haploidentical cord blood transplantationHealth sciences : nature.com subject feeds2hUnrelated cord blood transplantation for severe aplastic anemia using intensified immunoablative conditioning regimen leading to high engraftment and survivalHealth sciences : nature.com subject feeds2hIncluding hope in the treatment scheme—paradigms...
Tue Oct 29, 2019 16:34
American Journal of Epidemiology - Premenopausal Use of Progestogens and Cutaneous Melanoma Risk: A French Prospective Cohort StudyAbstractThe influence of sex hormones on melanoma risk has been suggested, but the influence of premenopausal use of progestogens on this cancer has never been investigated. E3N (Etude Epidémiologique auprès de femmes de l'Education Nationale) is a prospective cohort of 98,995 French women aged 40-65 years at inclusion. We used Cox models adjusted for age and melanoma...
Tue Oct 29, 2019 16:30
Καλλιεργώντας ευγνωμοσύνη,«Έχουμε πολύ καλή μνήμη για να θυμόμαστε όποιον μας πρόσβαλε και πολύ κακή για να θυμόμαστε κάποιον που μας έκανε μια χάρη» - Martin Luther King. Οι μεγάλοι δάσκαλοι της ανατολικής φιλοσοφίας μας διδάσκουν ότι το κλειδί της ευτυχίας είναι η ευγνωμοσύνη.E-Psychology.gr - Ψυχολογία, Άρθρα ψυχολογίας, Ψυχική Υγεία, ψυχοθεραπεία, συμβουλευτικήnowMark above section as read Food Safety News » Food RecallsBeef patties recalled for containing metalOSI Industries, LLC, in Fort Atkinson,...
Tue Oct 29, 2019 16:28
American Journal of Otolaryngology,Assessment of post-operative healing following endoscopic, transnasal, transsphenoidal pituitary surgery without formal sellar graftingPublication date: Available online 29 October 2019Source: American Journal of OtolaryngologyAuthor(s): Danny Jandali, Sarah Shearer, Richard Byrne, Peter Papagiannopoulos, Bobby A. Tajudeen, Pete S. BatraAbstractIntroductionMultiple options exist for sellar reconstruction after endoscopic transnasal, transsphenoidal surgery (TSS)...
Tue Oct 29, 2019 16:26
Formosan Journal of Surgery : Cowden syndrome diagnosed by Lhermitte–Duclos diseaseYuan-Shao Chen, Yoon Bin Chong, Chih-Hung Lin, Ann-Shung LieuFormosan Journal of Surgery 2019 52(5):197-199 Cowden syndrome (CS) is a rare genetic disease which puts patients at an increased risk of developing mucocutaneous lesion, multiple hamartomas, breast cancer, thyroid cancer, and Lhermitte–Duclos disease (LDD). This article reviews the role of LDD in the diagnosis of CS. It is important for all clinicians to...
Tue Oct 29, 2019 16:26
Relaciones entre el factor-1α inducido por hipoxia y los parámetros de la PET/TC con <sup>18</sup>F-FDG en el cáncer colorrectal: Publication date: Available online 28 October 2019Source: Revista Española de Medicina Nuclear e Imagen MolecularAuthor(s): Z. Hasbek, H. Ozer, S.A. Erturk, E. Erdiş, B. Yucel, E. Çiftçi, A. ÇakmakcilarResumenObjetivoEl factor inducible para hipoxia (HIF-1) tiene un papel crítico en la homeostasis del oxígeno y es un activador transcripcional de angiogénesis,...
Tue Oct 29, 2019 16:25
Medical News Today: What to know about pressure in the templesThere are many causes of pressure in the temples. They include certain types of headache, head injuries, and some more serious conditions. Learn more here.Featured Health News from Medical News Today16hMedical News Today: The best stretches for runnersRunning works many leg muscles and also puts a strain on the knees and back. Learn about 10 stretches that can help keep runners performing well in this article.Featured Health News from...
Tue Oct 29, 2019 16:25
Atmosphere, Vol. 10, Pages 660: Investigating the Influence of the Implementation of an Energy Development Plan on Air Quality Using WRF-CAMx Modeling Tools: A Case Study of Shandong Province in ChinaAtmosphere, Vol. 10, Pages 660: Investigating the Influence of the Implementation of an Energy Development Plan on Air Quality Using WRF-CAMx Modeling Tools: A Case Study of Shandong Province in China Atmosphere doi: 10.3390/atmos10110660 Authors: Luo He Yu He Zhang Ma In this paper, the Weather Research...
Tue Oct 29, 2019 16:24
ScienceDirect Publication: Journal of Genetics and Genomics,Acquisition of functional neurons by direct conversion: Switching the developmental clock directlyPublication date: Available online 28 October 2019Source: Journal of Genetics and GenomicsAuthor(s): Shuangquan Chen, Juan Zhang, Dongming Zhang, Jianwei JiaoAbstractIdentifying approaches for treating neurodegeneration is a thorny task but is important for a growing number of patients. Researchers have focused on discovering the underlying...
Tue Oct 29, 2019 16:21
MedWorm Allergy & Immunology News,Halloween Can Be Frightful for Kids With Allergies, AsthmaTitle: Halloween Can Be Frightful for Kids With Allergies, AsthmaCategory: Health NewsCreated: 10/26/2019 12:00:00 AMLast Editorial Review: 10/28/2019 12:00:00 AM (Source: MedicineNet Allergies General)MedWorm Allergy & Immunology NewsnowMark above section as read British Medical JournalElizabeth Donald Hibbardbmj;367/oct29_17/l6267/FAF1faElizabeth Donald Hibbard started her professional life in Aberdeen,...
Tue Oct 29, 2019 16:20
School Takeovers Are Risky. Rhode Island's Governor Thinks Hers Will Pay Off.Public schools in Rhode Island are a mess. The situation in the state is considered so extreme by activists, elected officials, students, and parents that last year they filed a class-action lawsuit claiming that Rhode Island had deprived the students of the literacy skills necessary to participate in a democracy. Things in Providence are particularly dire. When Johns Hopkins released a report about the state capital's public...
Tue Oct 29, 2019 16:18
Teens with autism can master daily living skills when parents teach, reach for iPads(Florida Atlantic University) Daily tasks are difficult for some people with autism because they often involve sequential steps. Since people with autism are strong visual learners, a study examined if parents could help their teens learn using portable, mainstream devices like an iPad. Similar studies have primarily targeted parents of young children with autism. Results show that video prompting interventions produced...
Tue Oct 29, 2019 16:16
GEO series , GSE100363 Identification of differentially expressed circRNA in gallbladder cancer compared with matched normal tissueContributor : Wang shouhuaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe hypothesized that the circRNA will play an important role in the progresion of gallbladder cancer. To test this hypothesis, we collect the gallbladder cancer and matched normal tissue from 4 different patients and examined the circRNA expression in these...
Tue Oct 29, 2019 16:15
AUDIOLOGY, Restoring the High-Frequency Dynamic Visual Acuity with a Vestibular Implant Prototype...
AUDIOLOGY,Restoring the High-Frequency Dynamic Visual Acuity with a Vestibular Implant Prototype in HumansIntroduction: The vestibular implant could become a clinically useful device in the near future. This study investigated the feasibility of restoring the high-frequency dynamic visual acuity (DVA) with a vestibular implant, using the functional Head Impulse Test (fHIT). Methods: A 72-year-old female, with bilateral vestibulopathy and fitted with a modified cochlear implant incorporating three...
Tue Oct 29, 2019 16:14
Latest Results for Conflict and Health,Effect of armed conflict on vaccination: evidence from the Boko haram insurgency in northeastern NigeriaAbstract Background Armed conflicts can have severe adverse effects on population health, both directly and indirectly, through the destruction of health care systems. This paper evaluates the causal effect of the Boko Haram insurgency in northeastern Nigeria on the vaccination rate. Methods By matching children's birth months and the months...Latest Results...
Tue Oct 29, 2019 16:11
Modern Pathology - Diagnosis of T-cell lymphoid proliferations of the skin: putting all the pieces togetherModern Pathology - Issue - nature.com science feedsnowMark above section as read New Scientist - Picture of the dayAI could solve baffling three-body problem that stumped Isaac NewtonThe three-body problem has vexed mathematicians and physicists for 300 years, but AI can find solutions far faster than any other method anyone has come up withNew Scientist - Picture of the day1mCan video games...
Tue Oct 29, 2019 16:10
Latest Results for Der Chirurg,Die demografische Perspektive auf maßgeschneiderte TherapieansätzeZusammenfassung Einleitung Der konstante Anstieg der Lebenserwartung seit über 170 Jahren ist eine der größten Leistungen der modernen Gesellschaft. Die Wahrscheinlichkeit, dass ein 80-Jähriger 100 Jahre wird, hat sich in Deutschland seit 1950 verzwanzigfacht. Dieser Sachverhalt hat verschiedenste Implikationen für den klinischen Alltag und therapeutische Leitlinien. In der Hernienversorgung sollte neben...
Tue Oct 29, 2019 16:08
Latest Results for Pediatric Cardiology,Intravenous Sotalol for the Treatment of Ventricular Dysrhythmias in an Infant on Extracorporeal Membrane OxygenationAbstract Sotalol is a class III anti-arrhythmic agent with beta receptor blocking properties. Intravenous (IV) sotalol may be useful to treat refractory atrial and ventricular arrhythmias. A report on the efficacy and safety of IV sotalol in an infant on extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT),...
Tue Oct 29, 2019 16:07
Latest Results for Current Microbiology,Pontibacter beigongshangensis sp. nov., Isolated from the Mash of WineAbstract A Gram-negative, aerobic, oval-shaped, and light red pigmented bacterium, designated T6-1T, was isolated from the mash of wine collected from a wine-making laboratory simulated fermenter located in Beijing, China. The optimal growth of T6-1T occurred at 30 °C, pH 7.0 with 1% NaCl. The sole respiratory quinone was menaquinone-7 (MK-7). The principal cellular fatty acids (>5%)...
Tue Oct 29, 2019 16:05
BMJ Open recent issues,Maternal and perinatal outcomes by planned place of birth in Australia 2000 - 2012: a linked population data studyObjectiveTo compare perinatal and maternal outcomes for Australian women with uncomplicated pregnancies according to planned place of birth, that is, in hospital labour wards, birth centres or at home. DesignA population-based retrospective design, linking and analysing routinely collected electronic data. Analysis comprised 2 tests and binary logistic regression...
Tue Oct 29, 2019 16:04
Plastic Surgery,Fat Grafting for Treatment of Facial SclerodermaPublication date: Available online 28 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Aurélie Daumas, Jeremy Magalon, Flore Delaunay, Maxime Abellan, Cécile Philandrianos, Florence Sabatier, Brigitte Granel, Guy MagalonPlastic Surgery3hFat Grafting for Facial Rejuvenation through Injectable Tissue Replacement and Regeneration: A Differential, Standardized, Anatomic ApproachPublication date: Available online 28 October 2019Source:...
Tue Oct 29, 2019 16:03
American Society for Stereotactic and Functional Neurosurgery,Three Cases of Trigeminal Neuralgia with Radiographic Absence of Meckel's CaveTrigeminal neuralgia (TN) is a debilitating but treatable disease. Classic TN has referable vascular compression of the trigeminal nerve, but rarely secondary sources of anatomic compression will present, including vascular malformations, aneurysms, or tumors. Understanding the etiology of the patients' symptoms leads to targeted treatment. Three patients presented...
Tue Oct 29, 2019 16:02
Latest Results for Maternal and Child Health Journal,Preconception and Prenatal Predictors of Early Experiences of Risk and Protection Among Alaska ChildrenAbstract Objectives Our objective was to identify preconception and prenatal predictors of early experiences of co-occurring risk and protective factors to help target prevention efforts to the highest-need families prior to the birth of the child. Methods Data were from the Alaska Longitudinal Child Abuse and Neglect Linkage project and the...
Tue Oct 29, 2019 16:01
Cancers, Vol. 11, Pages 1685: Intra-Patient Heterogeneity of Circulating Tumor Cells and Circulating Tumor DNA in Blood of Melanoma PatientsCancers, Vol. 11, Pages 1685: Intra-Patient Heterogeneity of Circulating Tumor Cells and Circulating Tumor DNA in Blood of Melanoma Patients Cancers doi: 10.3390/cancers11111685 Authors: Katharina Gorges Lisa Wiltfang Tobias M. Gorges Alexander Sartori Lina Hildebrandt Laura Keller Beate Volkmer Sven Peine Anna Babayan Ingrid Moll Stefan W. Schneider Sören Twarock...
Tue Oct 29, 2019 16:00
Latest Results for Journal of Endocrinological Investigation,The effect of previous treatment with bisphosphonate and renal impairment on the response to denosumab in osteoporosis: a 'real-life' studyAbstract Purpose To investigate changes in bone mineral density (BMD) following denosumab after previous bisphosphonate therapy and the impact of chronic kidney disease (CKD) on response. Methods A retrospective study of 134 patients (11 M, 123 F) aged [mean (SD)] 72 [11] years on denosumab was undertaken....
Tue Oct 29, 2019 16:00
Psycho-Oncology,Validation of a biopsychosocial distress screening tool, "You, Your Family and COH Are a Team"Abstract Objective We examined the psychometric properties of a biopsychosocial screening tool "You, Your Family and City of Hope are a Team" implemented via touchpad technology (YYFcore03) at a cancer center in newly diagnosed patients and patients on active treatment, with the primary objective to evaluate concurrent validity with screening criterion measures of depression and anxiety....
Tue Oct 29, 2019 15:59
Discrimination, Abuse, Harassment, and Burnout in Surgical Residency Training Burnout, a syndrome...
Discrimination, Abuse, Harassment, and Burnout in Surgical Residency TrainingBurnout, a syndrome of emotional exhaustion, cynicism, and reduced effectiveness at work, has been linked to poor health, alcoholism, depression, and suicide in physicians. Burnout has adverse effects on patient care and the physician workforce, since burned-out physicians are more likely to report…NEJM : ResearchMon Oct 28, 2019 02:00Mark above section as read Acta HistochemicaTraumatic Ulcerative Granuloma with Stromal...
Tue Oct 29, 2019 15:58
Latest Results for BMC Oral Health,Milled versus moulded mock-ups based on the superimposition of 3D meshes from digital oral impressions: a comparative in vitro study in the aesthetic areaAbstract Background Aesthetic porcelain veneers proved to be a long-term reliable prosthetic solution, ensuring minimal invasiveness. The use of veneers requires an adhesive cementation technique, so maintaining as much enamel as possible is to ensure lasting success. A diagnostic mock-up is a key tool that allows...
Tue Oct 29, 2019 15:57
Archives of Physical Medicine and Rehabilitation,Refugees and Rehabilitation: Our Fight Against the "Globalization of Indifference"Publication date: Available online 28 October 2019Source: Archives of Physical Medicine and RehabilitationAuthor(s): Michel D. Landry, Joost van Wijchen, Djenana Jalovcic, Carina Boström, Anna Pettersson, Maria Nordheim AlmeArchives of Physical Medicine and Rehabilitation15:40Mark above section as read Evolutionary Biology News -- ScienceDailyRed algae thrive despite...
Tue Oct 29, 2019 15:56
Penetrance of Malignant Hyperthermia, In a multicenter case-control study of 229 genotype-positive subjects with previous recorded exposure to trigger anesthetics, there were 93 malignant hypothermia cases, for an overall penetrance for the analyzed RYR1 mutations of 40.6%. The probability of developing malignant hypothermia on exposure to triggers was 0.25 among all RYR1 mutation carriers and 0.76 in survivors of malignant hypothermia reactions (95% CI of the difference 0.41 to 0.59). Young age,...
Tue Oct 29, 2019 15:55
Measuring evolutionary independence: A pragmatic approach to species classificationAbstractAfter decades of debates about species concepts, there is broad agreement that species are evolving lineages. However, species classification is still in a state of disorder: different methods of delimitation lead to competing outcomes for the same organisms, and the groups recognised as species are of widely different kinds. This paper considers whether this problem can be resolved by developing a unitary...
Tue Oct 29, 2019 15:54
Cross-cultural adaption and validation of the Chronic Otitis Media Questionnaire 12 (COMQ-12) in the Italian languageAbstractPurposeThe evaluation of Health-Related Quality of Life (HRQoL) in patients with chronic otitis media COM has gained attention over the past years and several questionnaires have been developed to evaluate it in affected patients. The Chronic Otitis Media Questionnaire 12 (COMQ-12) is a widely used disease-specific tool that evaluates the severity of symptoms, the specific...
Tue Oct 29, 2019 15:54
Application of different carbohydrates to produce squash puree based edible sheetAbstractThe production possibility of squash puree-containing edible sheet and its improvement by different hydrocolloids were studied. In this study, two hydrocolloids [carboxymethyl cellulose (CMC) and tragacanth gum] and also one plasticizer (glycerol) were used to produce squash puree-based edible sheets and optimization was performed to produce an edible sheet sample with the optimum properties. The results revealed...
Tue Oct 29, 2019 15:53
Interleukin-1 Genotype in Periodontitis,AbstractThis paper presents the current knowledge concerning the role of polymorphisms of IL1A and IL1B genes in periodontitis. Attention has been paid to the role of IL-1 in the pathogenesis of the disease, and to the significance of a genetic test, investigating the presence of composite two polymorphisms of IL-1 gene, as a risk factor for severe periodontitis. The significance of this test for prevention of periodontitis and its therapy has been discussed....
Tue Oct 29, 2019 15:53
The effect of endophytic bacteria on in vitro shoot growth of Prunus yedoensis and its identification and eliminationAbstractTissue cultures of Prunus yedoensis, a famous ornamental tree species, are important to mass-propagate true-to-type plants. Within in vitro cultures, bacterial contamination of explants hinders the propagation of sustainable cultures. Negative effects of endophytic bacteria vary from leaf yellowing to shoot-tip necrosis, ultimately resulting in shoot death. Explants with an...
Tue Oct 29, 2019 15:52
Vermamoeba vermiformis in hospital network: a benefit for Aeromonas hydrophilaAbstractAeromonas hydrophila, considered as an emerging pathogen, is increasingly involved in opportunistic human infections. This bacterium, mainly present in aquatic environments, can therefore develop relationships with the free-living amoeba Vermamoeba vermiformis in hospital water networks. We showed in this study that the joint presence of V. vermiformis and A. hydrophila led to an increased bacterial growth in the...
Tue Oct 29, 2019 15:52
DO REGIONAL NERVE BLOCKS PRIOR TO BIMAXILLARY SURGERY REDUCE POST-OPERATIVE PAIN?Publication date: Available online 28 October 2019Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Vikram Shetty, Bylapudi BhanuPrakash, Anirudh Yadav, Nanda Kishore P, Akash MenonAbstractPurposeAny elective surgery should be as atraumatic to the patient as possible allowing for comfortable post-operative recovery. This study was carried out to evaluate the efficacy of pre-surgical regional blocks in reducing...
Tue Oct 29, 2019 15:51
Ginsenoside Rb1 alleviates ox-LDL-induced vascular endothelium senescence via the SIRT1/Beclin-1/autophagy axisOxidative low-density lipoprotein (ox-LDL) induces endothelium senescence and promotes atherosclerosis. Ginsenoside Rb1 (gRb1) has been proved to protect HUVECs, but its effect on ox-LDL induced endothelium senescence and underlying mechanism remains unknown. This study is to explore the involvement of the SIRT1/Beclin-1/autophagy axis in the effect of gRb1 on protecting endothelium against...
Tue Oct 29, 2019 15:51
Can an automatic oscillometric device replace a mercury sphygmomanometer on blood pressure measurement? a systematic review and meta-analysisObjective: A mercury sphygmomanometer has been considered a gold standard for measuring blood pressure. However, by the Minamata Convention on Mercury, the traditional mercury sphygmomanometer is being replaced by an automated oscillometric device. This study aimed to provide scientific evidence to determine whether an automated oscillometric device can replace...
Tue Oct 29, 2019 15:51
Flavobacterium sangjuense sp. nov. isolated from sedimentAbstractA yellow-pigmented bacterial strain, GS03T, was isolated from sediment in a branch of the Nackdong River in Sangju, Korea. Cells were observed to be Gram-negative, aerobic and rod-shaped with gliding motility, and to be positive for catalase and oxidase. Growth was found to occur at 4–30 °C (optimum 25 °C), at pH 7.0–8.5 (optimum pH 7.5) and at NaCl 0% (optimum NaCl 0%, w/v). The major cellular fatty acids (> 10% of the total) were...
Tue Oct 29, 2019 15:50
DO REGIONAL NERVE BLOCKS PRIOR TO BIMAXILLARY SURGERY REDUCE POST-OPERATIVE PAIN?Any elective surgery should be as atraumatic to the patient as possible allowing for comfortable post-operative recovery. This study was carried out to evaluate the efficacy of pre-surgical regional blocks in reducing pain, discomfort and analgesic use in patients scheduled to undergo bimaxillary surgery.The Midfacial Advancement Line - a comparative evaluation of a new measurement method in orthognathic surgeryFor planning...
Tue Oct 29, 2019 15:50
Latest Results for Current Microbiology, Identification and Characterization of Cronobacter... Latest Results for Current Microbiology,Identification and Characterization of Cronobacter Strains Isolated from Environmental SamplesAbstract As an emerging food-borne pathogen, Cronobacter species are ubiquitous in the food and environment. In order to know the characteristics of Cronobacter spp. from the environment, we isolated Cronobacter spp. from soil and water, and then studied the molecular typing...
Tue Oct 29, 2019 10:05
Latest Results for Current Microbiology, Identification and Characterization of Cronobacter... Latest Results for Current Microbiology,Identification and Characterization of Cronobacter Strains Isolated from Environmental SamplesAbstract As an emerging food-borne pathogen, Cronobacter species are ubiquitous in the food and environment. In order to know the characteristics of Cronobacter spp. from the environment, we isolated Cronobacter spp. from soil and water, and then studied the molecular typing...
Tue Oct 29, 2019 10:05
Latest Results for Current Microbiology, Identification and Characterization of Cronobacter... Latest Results for Current Microbiology,Identification and Characterization of Cronobacter Strains Isolated from Environmental SamplesAbstract As an emerging food-borne pathogen, Cronobacter species are ubiquitous in the food and environment. In order to know the characteristics of Cronobacter spp. from the environment, we isolated Cronobacter spp. from soil and water, and then studied the molecular typing...
Tue Oct 29, 2019 10:05
Biomolecules, Vol. 9, Pages 664: Development of a Predictive Model to Induce Atherogenesis and Hepato-Renal Impairment in Female RatsBiomolecules, Vol. 9, Pages 664: Development of a Predictive Model to Induce Atherogenesis and Hepato-Renal Impairment in Female Rats Biomolecules doi: 10.3390/biom9110664 Authors: Lucas Pires Guarnier Paulo Vitor Moreira Romão Rhanany Alan Calloi Palozi Aniely Oliveira Silva Bethânia Rosa Lorençone Aline Aparecida Macedo Marques Ariany Carvalho dos Santos Roosevelt...
Tue Oct 29, 2019 10:00
Latest Results for Current Microbiology,Identification and Characterization of Cronobacter Strains Isolated from Environmental SamplesAbstract As an emerging food-borne pathogen, Cronobacter species are ubiquitous in the food and environment. In order to know the characteristics of Cronobacter spp. from the environment, we isolated Cronobacter spp. from soil and water, and then studied the molecular typing and antibiotic resistance characteristics of these isolates. In 2016, 141 soil and water samples...
Tue Oct 29, 2019 10:00
European Review,MicroRNA-330-5p promotes the development of osteosarcoma by regulating SPRY2OBJECTIVE: MicroRNA is an endogenous, non-coding small RNA that has a significant role in regulating organisms and pathology. Previous studies have demonstrated that microRNA-330-5p was a cancer-promoting gene. However, the role of microRNA-330-5p in osteosarcoma (OS) has not been reported. The aim of this work was to explore the characteristics of microRNA-330-5p expression in OS, and to further study its...
Tue Oct 29, 2019 09:58
Latest Results for Annals of Biomedical Engineering,The Effect of Downsizing on the Normal Tricuspid AnnulusAbstract Tricuspid annuloplasty is a surgical procedure that cinches the valve's annulus in order to reduce regurgitant blood flow. One of its critical parameters is the degree of downsizing. To provide insight into the effect of downsizing, we studied the annulus of healthy sheep during suture annuloplasty. To this end, we implanted fiduciary markers along the annulus of sheep and subsequently...
Tue Oct 29, 2019 09:55
BioMed Research International,Quercetin and Quercitrin Attenuates the Inflammatory Response and Oxidative Stress in LPS-Induced RAW264.7 Cells: In Vitro Assessment and a Theoretical ModelBackground. Nowadays, atmospheric pollutants, ultraviolet rays, and other factors cause the imbalance of cell redox, resulting in skin oxidative damage. There is an interaction between inflammatory response and oxidative stress, which often involve networks of reactions and serve to amplify each other. Quercetin...
Tue Oct 29, 2019 09:54
pubmed: thyroid cancer,Association between TERT promoter mutations and clinical behaviors in differentiated thyroid carcinoma: a systematic review and meta-analysis.Related ArticlesAssociation between TERT promoter mutations and clinical behaviors in differentiated thyroid carcinoma: a systematic review and meta-analysis. Endocrine. 2019 Oct 26;: Authors: Yang J, Gong Y, Yan S, Chen H, Qin S, Gong R Abstract BACKGROUND: The association between telomerase reverse transcriptase (TERT) promoter mutations...
Tue Oct 29, 2019 09:53
Infectious disorders drug targets, Utility of CD4 Cell Count and Viral Load Assay in Hospitalized...
Infectious disorders drug targets,Utility of CD4 Cell Count and Viral Load Assay in Hospitalized Patients with Known HIV Infection: High Value Care Exercise.Related ArticlesUtility of CD4 Cell Count and Viral Load Assay in Hospitalized Patients with Known HIV Infection: High Value Care Exercise. Infect Disord Drug Targets. 2019 Oct 11;: Authors: Lal A, Abraham GM Abstract PURPOSE: Healthcare spending as percentage of GDP is at all-time high and continues to rise in the United States. The Centers...
Tue Oct 29, 2019 09:52
J BUON. 2019 Jul-Aug;24(4):1738.The impact of receptor conversion on treatment efficacy and survival in breast cancer patients with brain metastases: Still debatable issue?Abduyev Z1, Altundag K.Author information1MKA Breast Cancer Clinic, Tepe Prime, Cankaya, 06800 Ankara, TURKEY.PMID: 31646839Free full textSimilar articlesIcon for Zerbinis, Medical PublicationsSelect item 316468382.J BUON. 2019 Jul-Aug;24(4):1737.Thymidylate synthase expression at metastatic site might be more correlated with response...
Tue Oct 29, 2019 09:50
BMC Public Health. 2019 Jul 25;19(1):1001. doi: 10.1186/s12889-019-7330-z.Estimates of past and future time trends in age-specific breast cancer incidence among women in Karachi, Pakistan: 2004-2025.Zaheer S1,2, Shah N3, Maqbool SA4, Soomro NM5.Author information1Department of Statistics, University of Karachi, Karachi, Pakistan. sidra.zaheer@duhs.edu.pk.2School of Public Health, Dow University of Health Sciences, OJHA Campus, Suparco road, Karachi, Pakistan. sidra.zaheer@duhs.edu.pk.3School of Public...
Tue Oct 29, 2019 09:50
Future Oncol. 2019 Oct 25. doi: 10.2217/fon-2019-0365. [Epub ahead of print]Relationship of single nucleotide polymorphisms and haplotype interaction of mitochondrial unfolded protein response pathway genes with head and neck cancer.Ahmed MW1, Mahjabeen I1, Gul S1, Khursheed A1, Mehmood A1, Kayani MA1.Author information1Cancer Genetics & Epigenetics Lab, Department of Biosciences, COMSATS University Islamabad, Park Road Tarlai Kalan, Islamabad Pakistan.AbstractAim: In this study, we evaluated...
Tue Oct 29, 2019 09:49
Future Drug Discov. 2019 Oct 11;1(2):FDD18. doi: 10.4155/fdd-2019-0021.Practical considerations for the implementation of adaptive designs for oncology Phase I dose-finding trials.Wei L1, Pan X1, Fernandez S1.Author information1Center for Biostatistics, Department of Biomedical Informatics, College of Medicine, The Ohio State University, 1800 Cannon Dr. Columbus, OH 43210, USA.AbstractThe traditional 3 + 3 design continues to be commonly used for Phase I dose-finding oncology trials, despite increasing...
Tue Oct 29, 2019 09:48
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,