Latest Results for Current Microbiology,Identification and Characterization of Cronobacter Strains Isolated from Environmental SamplesAbstract As an emerging food-borne pathogen, Cronobacter species are ubiquitous in the food and environment. In order to know the characteristics of Cronobacter spp. from the environment, we isolated Cronobacter spp. from soil and water, and then studied the molecular typing and antibiotic resistance characteristics of these isolates. In 2016, 141 soil and water samples...
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European Review,MicroRNA-330-5p promotes the development of osteosarcoma by regulating SPRY2OBJECTIVE: MicroRNA is an endogenous, non-coding small RNA that has a significant role in regulating organisms and pathology. Previous studies have demonstrated that microRNA-330-5p was a cancer-promoting gene. However, the role of microRNA-330-5p in osteosarcoma (OS) has not been reported. The aim of this work was to explore the characteristics of microRNA-330-5p expression in OS, and to further study its...
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Latest Results for Annals of Biomedical Engineering,The Effect of Downsizing on the Normal Tricuspid AnnulusAbstract Tricuspid annuloplasty is a surgical procedure that cinches the valve's annulus in order to reduce regurgitant blood flow. One of its critical parameters is the degree of downsizing. To provide insight into the effect of downsizing, we studied the annulus of healthy sheep during suture annuloplasty. To this end, we implanted fiduciary markers along the annulus of sheep and subsequently...
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BioMed Research International,Quercetin and Quercitrin Attenuates the Inflammatory Response and Oxidative Stress in LPS-Induced RAW264.7 Cells: In Vitro Assessment and a Theoretical ModelBackground. Nowadays, atmospheric pollutants, ultraviolet rays, and other factors cause the imbalance of cell redox, resulting in skin oxidative damage. There is an interaction between inflammatory response and oxidative stress, which often involve networks of reactions and serve to amplify each other. Quercetin...
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pubmed: thyroid cancer,Association between TERT promoter mutations and clinical behaviors in differentiated thyroid carcinoma: a systematic review and meta-analysis.Related ArticlesAssociation between TERT promoter mutations and clinical behaviors in differentiated thyroid carcinoma: a systematic review and meta-analysis. Endocrine. 2019 Oct 26;: Authors: Yang J, Gong Y, Yan S, Chen H, Qin S, Gong R Abstract BACKGROUND: The association between telomerase reverse transcriptase (TERT) promoter mutations...
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Infectious disorders drug targets, Utility of CD4 Cell Count and Viral Load Assay in Hospitalized...
Infectious disorders drug targets,Utility of CD4 Cell Count and Viral Load Assay in Hospitalized Patients with Known HIV Infection: High Value Care Exercise.Related ArticlesUtility of CD4 Cell Count and Viral Load Assay in Hospitalized Patients with Known HIV Infection: High Value Care Exercise. Infect Disord Drug Targets. 2019 Oct 11;: Authors: Lal A, Abraham GM Abstract PURPOSE: Healthcare spending as percentage of GDP is at all-time high and continues to rise in the United States. The Centers...
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J BUON. 2019 Jul-Aug;24(4):1738.The impact of receptor conversion on treatment efficacy and survival in breast cancer patients with brain metastases: Still debatable issue?Abduyev Z1, Altundag K.Author information1MKA Breast Cancer Clinic, Tepe Prime, Cankaya, 06800 Ankara, TURKEY.PMID: 31646839Free full textSimilar articlesIcon for Zerbinis, Medical PublicationsSelect item 316468382.J BUON. 2019 Jul-Aug;24(4):1737.Thymidylate synthase expression at metastatic site might be more correlated with response...
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BMC Public Health. 2019 Jul 25;19(1):1001. doi: 10.1186/s12889-019-7330-z.Estimates of past and future time trends in age-specific breast cancer incidence among women in Karachi, Pakistan: 2004-2025.Zaheer S1,2, Shah N3, Maqbool SA4, Soomro NM5.Author information1Department of Statistics, University of Karachi, Karachi, Pakistan. sidra.zaheer@duhs.edu.pk.2School of Public Health, Dow University of Health Sciences, OJHA Campus, Suparco road, Karachi, Pakistan. sidra.zaheer@duhs.edu.pk.3School of Public...
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Future Oncol. 2019 Oct 25. doi: 10.2217/fon-2019-0365. [Epub ahead of print]Relationship of single nucleotide polymorphisms and haplotype interaction of mitochondrial unfolded protein response pathway genes with head and neck cancer.Ahmed MW1, Mahjabeen I1, Gul S1, Khursheed A1, Mehmood A1, Kayani MA1.Author information1Cancer Genetics & Epigenetics Lab, Department of Biosciences, COMSATS University Islamabad, Park Road Tarlai Kalan, Islamabad Pakistan.AbstractAim: In this study, we evaluated...
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Future Drug Discov. 2019 Oct 11;1(2):FDD18. doi: 10.4155/fdd-2019-0021.Practical considerations for the implementation of adaptive designs for oncology Phase I dose-finding trials.Wei L1, Pan X1, Fernandez S1.Author information1Center for Biostatistics, Department of Biomedical Informatics, College of Medicine, The Ohio State University, 1800 Cannon Dr. Columbus, OH 43210, USA.AbstractThe traditional 3 + 3 design continues to be commonly used for Phase I dose-finding oncology trials, despite increasing...
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Latest Results for Obesity Surgery,Impact of Bariatric Surgery on Female Sexual Function in Obese Patients: a Meta-AnalysisAbstract We aimed to make a meta-analysis regarding the effect of bariatric surgery on female sexual function. PubMed, EMBASE, and CENTRAL were searched from database inception through August 2019. Articles were eligible for inclusion if they examined the effect of bariatric surgery on obese women's sexual function assessed by the Female Sexual Functioning Index (FSFI) or/and...
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J Immunother Cancer. 2018 Jun 6;6(1):48. doi: 10.1186/s40425-018-0368-0.Effect of neoadjuvant chemotherapy on the immune microenvironment in non-small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches.Parra ER1, Villalobos P2, Behrens C3, Jiang M2, Pataer A4, Swisher SG4, William WN Jr3, Zhang J5, Lee J6, Cascone T3, Heymach JV3, Forget MA7, Haymaker C7, Bernatchez C7, Kalhor N8, Weissferdt A8, Moran C8, Zhang J3, Vaporciyan A4, Gibbons DL3, Sepesi B9,...
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BMJ Open. 2018 Oct 15;8(10):e022752. doi: 10.1136/bmjopen-2018-022752.Obstructive sleep apnoea and the risk for coronary heart disease and type 2 diabetes: a longitudinal population-based study in Finland.Strausz S1,2,3, Havulinna AS3,4, Tuomi T3,5,6, Bachour A7, Groop L3,8, Mäkitie A9, Koskinen S4, Salomaa V4, Palotie A3,10,11,12,13, Ripatti S#3,14, Palotie T#1,2.Author information1Department of Oral and Maxillofacial Diseases, Helsinki University Hospital, Helsinki, Finland.2Orthodontics, Department...
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Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Sep 7;54(9):647-654. doi: 10.3760/cma.j.issn.1673-0860.2019.09.002.[Lateral endoscopic transorbital approach to middle skull base: anatomical and surgical practice study].[Article in Chinese; Abstract available in Chinese from the publisher]Li J1, Guo SL2, Sun W1, Wang QM1, Wen YH1, Wei FQ1, Wen WP1.Author information1Department of Otorhinolaryngology Head and Neck Surgery, the First Affiliated Hospital of Sun Yat-sen University, the Institute of...
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BMC Palliat Care. 2019 Oct 23;18(1):85. doi: 10.1186/s12904-019-0468-8.Efficacy and cost-utility of the eHealth application 'Oncokompas', supporting patients with incurable cancer in finding optimal palliative care, tailored to their quality of life and personal preferences: a study protocol of a randomized controlled trial.Schuit AS1,2, Holtmaat K1,2, Hooghiemstra N1,2, Jansen F1,2,3, Lissenberg-Witte BI4, Coupé VMH4, van Linde ME5, Becker-Commissaris A6, Reijneveld JC7, Zijlstra JM8, Sommeijer...
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Oral Oncol. 2019 Oct 21:104449. doi: 10.1016/j.oraloncology.2019.104449. [Epub ahead of print]Co-occurrence of Warthin's tumor with oral squamous cell carcinoma - Overlapping risk factors and implications.Harshada B1, Karishma Madhusudan D2, Alka Dinesh K1, Punnya A1, Seema H1, Rebekah C1.Author information1Department of Oral Pathology and Microbiology, KLE VK Institute of Dental Sciences, KLE Academy of Higher Education and Research [KLE University], Belagavi, Karnataka 590010, India.2Department...
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J Otolaryngol Head Neck Surg. 2019 Oct 24;48(1):54. doi: 10.1186/s40463-019-0380-5.Impact of marginalization on tobacco use in individuals diagnosed with head and neck Cancer.Scott GM1, Best C2, Fung K3, Gupta M4, Sommer DD4, Szeto C5, Micomonaco DC5.Author information1Department of Rural and Northern Health, Laurentian University, Sudbury, Canada. gracemargaretscott@gmail.com.2Department of Otolaryngology-Head & Neck Surgery, University of Ottawa, Ottawa, Canada.3Department of Otolaryngology-Head...
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J Voice. 2019 Oct 22. pii: S0892-1997(19)30323-6. doi: 10.1016/j.jvoice.2019.09.010. ,Compensatory Movement of Contralateral Vocal Folds in Patients With Unilateral Vocal Fold Paralysis.Xu X1, Zhuang P2, Wilson A3, Jiang JJ4.Author information1Division of Otolaryngology, Xiamen University Zhongshan Hospital, Xiamen, Fujian, China.2Division of Otolaryngology, Xiamen University Zhongshan Hospital, Xiamen, Fujian, China. Electronic address: peiyun_zhuang@yahoo.com.3Department of Communication Science...
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Microvascular free tissue transfer and cochlear implants: A case series and literature review.Lindquist NR1, Vinh DB1, Appelbaum EN1, Vrabec JT2, Huang AT1.Author information1Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, U.S.A.2Department of Otolaryngology, Houston Methodist Hospital, Houston, Texas, U.S.A.AbstractOBJECTIVE:The use of microvascular free tissue transfer (MVFTT) for defects of the scalp and lateral temporal bone in patients with cochlear...
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Improved Survival with Immunotherapy but Lack of Synergistic Effect with Radiation for Stage IV Melanoma of the Head and Neck.Babcock B, Rodrigues M, Kearns D, Solomon N, Reeves ME, Senthil M, Garberoglio CA, Namm JP.AbstractProspective randomized studies have demonstrated a survival benefit of immunotherapy in stage IV cutaneous melanoma. Some retrospective studies have hypothesized a synergistic effect of radiation and immunotherapy. Our objective was to identify whether there is a survival benefit...
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Rare Cancers,Tumor Suppression of Ras GTPase-Activating Protein RASA5 through Antagonizing Ras Signaling Perturbation in Carcinomas.Related ArticlesTumor Suppression of Ras GTPase-Activating Protein RASA5 through Antagonizing Ras Signaling Perturbation in Carcinomas. iScience. 2019 Oct 08;21:1-18 Authors: Li L, Fan Y, Huang X, Luo J, Zhong L, Shu XS, Lu L, Xiang T, Chan ATC, Yeo W, Chen C, Chan WY, Huganir RL, Tao Q Abstract Aberrant RAS signaling activation is common in cancers with even few Ras...
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The Greek Endocrine Society,Potential clinical variants detected in mitochondrial DNA D-loop hypervariable region I of patients with non-alcoholic steatohepatitis.Related ArticlesPotential clinical variants detected in mitochondrial DNA D-loop hypervariable region I of patients with non-alcoholic steatohepatitis. Hormones (Athens). 2019 Oct 26;: Authors: Hasturk B, Yilmaz Y, Eren F Abstract PURPOSE: Non-alcoholic steatohepatitis (NASH) is a mitochondrial disease. However, the underlying role of...
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Induction of developmental toxicity and cardiotoxicity in zebrafish embryos/larvae by acetyl-11-keto-β-boswellic acid (AKBA) through oxidative stress.Han L1, Xia Q1, Zhang L2, Zhang X1, Li X1, Zhang S1, Wang L1, Liu C3, Liu K1.Author information1Biology Institute, Qilu University of Technology (Shandong Academy of Sciences) , Jinan , People's Republic of China.2Biological Science Section, Therapeutic Good Administration , Symonston , Australia.3Tianjin Center for New Drug Evaluation and Research,...
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The Journal of Clinical Endocrinology & Metabolism,Fertility and pregnancy in women with hypopituitarism: a systematic literature review.Related ArticlesFertility and pregnancy in women with hypopituitarism: a systematic literature review. J Clin Endocrinol Metab. 2019 Oct 25;: Authors: Vila G, Fleseriu M Abstract CONTEXT: Human reproduction is mainly governed from the hypothalamic-adrenal-gonadal (HPG) axis, which controls both ovarian morphology and function. Disturbances in the secretion...
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Hemangioblastoma Instead of Renal Cell Carcinoma Plays a Major Role in the Unfavorable Overall Survival of Von Hippel-Lindau Disease Patients.Zhou B1,2,3,4, Wang J4,5, Liu S1,2,3, Peng X1,2,3,6, Hong B1,2,3, Zhou J1,2,3, Ma K1,2,3, Zhang J1,2,3, Cai L1,2,3, Gong K1,2,3.Author information1Department of Urology, Peking University First Hospital, Beijing, China.2Institute of Urology, Peking University, Beijing, China.3National Urological Cancer Center, Beijing, China.4Department of Urology, Beijing...
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Molecular Carcinogenesis,Single‐nucleotide polymorphism rs13426236 contributes to an increased prostate cancer risk via regulating MLPH splicing variant 4Abstract A prostate cancer risk single‐nucleotide polymorphism (SNP), rs13426236, is significantly associated with melanophilin (MLPH) expression. To functionally characterize role of the rs13426236 in prostate cancer, we first performed splicing‐specific expression quantitative trait loci analysis and refined the significant association of rs13426236...
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[Research progress in glycogen metabolism reprogramming in sepsis associated immune cells].[Article in Chinese]Wang D1, Liu M2, Lyu X2.Author information1Department of Anesthesiology, China-Japan Friendship Hospital of Jilin University, Changchun 130033, Jilin, China.2Department of Anesthesiology, Shanghai Pulmonary Hospital of Tongji University, Shanghai 200433, China. Corresponding author: Lyu Xin, Email: xinlv@126.com.AbstractMetabolic reprogramming is the response of cells to environmental changes,...
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Mobile applications to detect hearing impairment: opportunities and challenges.Swanepoel W1, De Sousa KC1, Smits C2, Moore DR3.Author information1Department of Speech-Language Pathology and Audiology, University of Pretoria, Private Bag X20, Hatfield 0028, South Africa.2Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.3Communication Sciences Research Center, Cincinnati Children's Hospital, Ohio, United States of America.PMID: 31656337 PMCID: PMC6796675...
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Association française pour l'étude du cancer,[Lymph node management in endometrial cancer].Related Articles[Lymph node management in endometrial cancer]. Bull Cancer. 2019 Oct 21;: Authors: Owen C, Bendifallah S, Jayot A, Ilenko A, Arfi A, Boudy AS, Richard S, Varinot J, Thomassin-Naggara I, Bazot M, Daraï É Abstract In 2018, around 382,100 new cases of endometrial cancer (EC) were reported worldwide, accounting for about 4.4% of all new cases of cancer in women. In France, in 2018, the EC is the...
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Latest Results for Water, Air, & Soil Pollution,A Comparative Adsorption Study with Various Adsorbents for the Removal of Ciprofloxacin Hydrochloride from WaterAbstract In this study, the removal of ciprofloxacin hydrochloride (a fluoroquinolone antibiotic) by using various effective adsorbents such as activated carbon, montmorillonite, modified montmorillonite (commercial name Cloisite 20A), and alumina was investigated. Adsorption experiments were performed to determine and compare the adsorption...
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Environmental+Science+and+Pollution+Research,Atrazine exposure in gestation and breastfeeding affects Calomys laucha sperm cellsAbstract The present study evaluated the effects of low doses of atrazine administered during gestation and breastfeeding on sperm characteristics of the wild rodent Calomys laucha. Adult females were divided into groups of 10 and administered different doses of atrazine through gavage, during gestational or breastfeeding period. At 3 months of age, the F1 adult male progeny...
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Latest Results for International Journal of Clinical Pharmacy,Patients' clinical information requirements to apply the STOPP/START criteriaAbstract Background The STOPP/START criteria are an explicit tool to detect potentially inappropriate medications (PIMs). Patient clinical information may not be available in all settings. Objective To identify patient clinical information needed to apply the STOPP/START criteria. Setting: Four nursing homes in Portugal. Methods First, a theoretical analysis...
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NEJM Journal Watch: Physician's First Watch , Anti-inflammatory Drugs Show Promise for Depression...
NEJM Journal Watch: Physician's First Watch ,Anti-inflammatory Drugs Show Promise for Depression TreatmentAnti-inflammatory agents might help treat major depressive disorder (MDD), according to a meta-analysis in the Journal of Neurology, Neurosurgery & Psychiatry. The analysis included...NEJM Journal Watch: Physician's First Watch RSS Feed6hResearchers: Cannabinoids Shouldn't Be Used for Mental Health DisordersCannabinoids should not be used to treat mental health disorders, researchers conclude...
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Latest Results for Langenbeck's Archives of Surgery,Preoperative total cholesterol-lymphocyte score as a novel immunonutritional predictor of survival in gastric cancerAbstract Purpose Immunonutritional status is a known prognostic correlate in the context of gastric cancer (GC). In the present study, we investigated the prognostic relevance of a lipid profile-based immunonutritional score in patients with GC. Methods Data pertaining to 224 patients with stage II and III GC who underwent curative...
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Prenatal Diagnosis,Mother‐to‐child transmission of hepatitis B virus after amniocentesis: A retrospective matched cohort study"Prenatal DiagnosisnowPrediction model of postnatal renal function in fetuses with lower urinary tract obstruction (LUTO)—Development and internal validationAbstract Objective To develop a prediction model of postnatal renal function in fetuses with lower urinary tract obstruction (LUTO) based on fetal ultrasound parameters and amniotic fluid volume. Methods Retrospective...
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Percutaneous cryoablation of subcapsular hepatocellular carcinoma: a retrospective study of 57 cases.Wang F1, Ma J2, Wu L3, Li N1, Luo R1, Wei G1, Yang J1.Author information1Department of Interventional Radiology, Changhai Hospital, Second Military Medical University, Shanghai, China.2Department of Radiology, The First Hospital of Jiaxing, Zhejiang, China.3Department of Oncology, Tengzhou Central People's Hospital, Shandong, China.AbstractPURPOSE:This study aims to evaluate the safety and effectiveness...
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As-needed ICS-LABA in Mild Asthma: What Does the Evidence Say? Abstract, fourth to last sentence,...
As-needed ICS-LABA in Mild Asthma: What Does the Evidence Say?Abstract, fourth to last sentence, which currently reads:Latest Results for DrugsnowMark above section as read Journal of Medical Imaging and Radiation OncologyImaging appearance of an Extravascular Implantable Cardioverter DefibrillatorJournal of Medical Imaging and Radiation Oncology2hMark above section as read RSC - Chem. Commun. latest articlesA Colorimetric and Fluorescent Dual-Modal Displacement Probe Based on Host-Assisted Modulation...
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Disease Markers,Circular RNAs Hsa_circ_0002715 and Hsa_circ_0035197 in Peripheral Blood Are Novel Potential Biomarkers for New-Onset Rheumatoid ArthritisThis study is aimed at exploring the levels of peripheral blood circular RNAs (circRNAs) as biomarker candidates for the diagnosis of new-onset rheumatoid arthritis (RA). The selected twenty-two circRNAs in peripheral blood from new-onset RA patients and healthy controls (HC) were determined by quantitative reverse transcription-polymerase chain...
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BMJ Open recent issues,Female reproductive history in relation to chronic obstructive pulmonary disease and lung function in UK biobank: a prospective population-based cohort studyObjectivesSex differences in respiratory physiology and predilection for developing chronic obstructive pulmonary disease (COPD) have been documented, suggesting that female sex hormones may influence pathogenesis. We investigated whether aspects of female reproductive health might play a role in risk of COPD among women....
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Odontology,Clinical efficacy of an Aloe Vera gel versus a 0.12% chlorhexidine gel in preventing traumatic ulcers in patients with fixed orthodontic appliances: a double-blind randomized clinical trialAbstract Traumatic oral ulceration (TOU) is one of the most common side effects of orthodontic treatments. The objective of this trial is to compare the clinical efficacy of an 80% Aloe Vera gel, prepared using a master formula, versus a commercial 0.12% Chlorhexidine (CHX) gel for TOU prevention in...
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pubmed: dysphagia,Primary laryngectomy versus salvage laryngectomy: A comparison of outcomes in the chemoradiation era.Related ArticlesPrimary laryngectomy versus salvage laryngectomy: A comparison of outcomes in the chemoradiation era. Laryngoscope. 2019 Oct 25;: Authors: Sullivan CB, Ostedgaard KL, Al-Qurayshi Z, Pagedar NA, Sperry SM Abstract OBJECTIVE: To compare primary total laryngectomy (TL) versus salvage TL and analyze the functional outcomes, complications, recurrence rates, and survival....
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pubmed: melanoma,Electrochemical aptamer-based determination of protein tyrosine kinase-7 using toehold-mediated strand displacement amplification on gold nanoparticles and graphene oxide.Related ArticlesElectrochemical aptamer-based determination of protein tyrosine kinase-7 using toehold-mediated strand displacement amplification on gold nanoparticles and graphene oxide. Mikrochim Acta. 2019 Oct 26;186(11):720 Authors: Li Z, Zhou Z, Xue N, Wu S, Miao X Abstract An electrochemical method is described...
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Gabapentinoids appear increasingly to be prescribed, off-label, for cancer painBetween 2005 and 2015, as the opioid crisis in America came into focus, prescriptions for gabapentinoid medications -- gabapentin and pregabalin -- to adults with cancer saw a two-fold increase, a new study has found.Cancer News -- ScienceDaily9hLenalidomide may delay onset of myeloma-related bone, organ damageThe largest randomized trial in asymptomatic patients with smoldering multiple myeloma suggests that lenalidomide,...
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Cancer,Prognostic relevance of the Golgi mannosidase MAN1A1 in ovarian cancer: impact of N-glycosylation on tumour cell aggregationBritish Journal of Cancer, Published online: 29 October 2019; doi:10.1038/s41416-019-0607-2Prognostic relevance of the Golgi mannosidase MAN1A1 in ovarian cancer: impact of N-glycosylation on tumour cell aggregationCancer5hMark above section as read Cancer biology and therapyMajor challenges in accurate mutation detection of multifocal lung adenocarcinoma by next-generation...
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Comparative Clinical Pathology,Antifungal activity of ethanolic extracts of Ocimum gratissimum and Vernonia amygdalina leaves against dermatomycotic agents isolated from domestic animals in South Eastern NigeriaAbstract Dermatomycoses, often caused by both dermatophytic and non dermatophytic fungi, affect the epidermis, nail, and hair. There is an increase in antifungal resistance against antimycotics of many dermatophytes and non-dermatophytes, and this has posed a serious global challenge. Therefore,...
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Latest Plastic Surgery & Aesthetic Medicine,Half of Surgical Residents Report MistreatmentMore frequent exposure to discrimination, abuse, and harassment may explain higher burnout rates among female general surgery residents.Latest Plastic Surgery & Aesthetic Medicine Headlines12hMark above section as read Plastic and Reconstructive Surgery - Current IssueEstablishment of New Asymmetrical Grafts in Secondary Nasal Deformity RepairNo abstract availablePlastic and Reconstructive Surgery -...
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European Review » Stem Cell,Steroids and growth factors in oral squamous cell carcinoma: useful source of dental-derived stem cells to develop a steroidogenic model in new clinical strategiesOBJECTIVE: Head and neck region is involved in a high percentage of malignant lesions, and oral squamous cell carcinoma (OSCC) is undoubtedly the most frequently found, accounting for over 90% of malignant tumors. Hormone receptor overexpression, like Estrogen Receptor (ER), Progesterone Receptor (PR) and Endothelial...
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Auris Nasus Larynx,Update review of pain control methods of tonsil surgeryPain after tonsil surgery is troublesome because it causes discomfort. In addition, handling patients with postoperative pain is challenging to otolaryngologists. Many laboratory studies have assessed the use of analgesics and surgical techniques to discover methods for effective control of postoperative pain associated with tonsil surgery. In this review article, we summarize and provide a comprehensive overview of current...
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Helicobacter pylori inhibits GKN1 expression via the CagA/p‐ERK/AUF1 pathwayAbstract Background Recent studies have shown that gastrokine 1 (GKN1), an important tumor suppressor gene, is downregulated in Helicobacter pylori (H. pylori) infected gastric mucosa and gastric cancer. However, the underlying mechanism is poorly understood. Herein, we investigated the potential mechanism of H. pylori‐induced GKN1 downregulation. Materials and methods GKN1 and AU‐rich element RNA‐binding factor 1 (AUF1)...
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Histochemical Approach for Simultaneous Detection of Ectonucleotidase and Alkaline Phosphatase Activities in Tissues.Losenkova K1, Paul M1, Irjala H2, Jalkanen S1, Yegutkin GG3.Author information1MediCity Research Laboratory, University of Turku, Turku, Finland.2Department of Otorhinolaryngology, Head and Neck Surgery, Turku University Hospital and Turku University, Turku, Finland.3MediCity Research Laboratory, University of Turku, Turku, Finland. gennady.yegutkin@utu.fi.AbstractStudies on pathophysiology...
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Assessment of Cell Adhesion After Purinoceptor Activation.Martínez-García JJ1, Pelegrín P2.Author information1Biomedical Research Institute of Murcia (IMIB), Clinical University Hospital Virgen de la Arrixaca, Murcia, Spain.2Biomedical Research Institute of Murcia (IMIB), Clinical University Hospital Virgen de la Arrixaca, Murcia, Spain. pablo.pelegrin@imib.es.AbstractCell adhesion is a characteristic feature of phagocytic myeloid cells, which is important for several inflammatory processes, such...
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Evaluating the responses of taxa in the orders Ephemeroptera, Plecoptera and Trichoptera (EPT) to sediment stress in the Tsitsa River and its tributaries, Eastern Cape, South Africa.Akamagwuna FC1, Mensah PK2, Nnadozie CF2, Odume ON3.Author information1Unilever Centre for Environmental Water Quality, Institute for Water Research, Rhodes University, P.O. Box 94, Grahamstown, 6140, South Africa. akamagwunafrank@yahoo.com.2Unilever Centre for Environmental Water Quality, Institute for Water Research,...
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Water quality assessment of a neotropical pampean lowland stream using a phytoplankton functional trait approach.Frau D1, Medrano J2, Calvi C3, Giorgi A4.Author information1Laboratorio de Plancton, Instituto Nacional de Limnología (CONICET-UNL), Ciudad Universitaria Paraje El Pozo S/N, Santa Fe, Argentina. diegofrau@gmail.com.2Facultad de Ciencias y Tecnología, Universidad Autónoma de Entre Ríos, Ruta Provincial No. 11. Km 10.5, Oro Verde, Argentina.3Facultad de Humanidades y Ciencias, Universidad...
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The Genetics and Biochemistry of Cell Wall Structure and Synthesis in Neurospora crassa, a Model Filamentous Fungus.Patel PK1, Free SJ1.Author information1Department of Biological Sciences, SUNY University at Buffalo, Buffalo, NY, United States.AbstractThis review discusses the wealth of information available for the N. crassa cell wall. The basic organization and structure of the cell wall is presented and how the wall changes during the N. crassa life cycle is discussed. Over forty cell wall glycoproteins...
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In silico Selection and Experimental Validation of FDA-Approved Drugs as Anti-quorum Sensing Agents.Mellini M1, Di Muzio E1, D'Angelo F1, Baldelli V1, Ferrillo S1, Visca P1, Leoni L1, Polticelli F1,2, Rampioni G1.Author information1Department of Science, University Roma Tre, Rome, Italy.2National Institute of Nuclear Physics, Roma Tre Section, Rome, Italy.AbstractThe emergence of antibiotic resistant bacterial pathogens is increasing at an unprecedented pace, calling for the development of new therapeutic...
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pubmed: "life sci"[jour]Involvement of the PKA pathway and inhibition of voltage gated Ca2+ channels in antihyperalgesic activity of Lippia grata/β-cyclodextrin.Related ArticlesInvolvement of the PKA pathway and inhibition of voltage gated Ca2+ channels in antihyperalgesic activity of Lippia grata/β-cyclodextrin. Life Sci. 2019 Oct 22;:116961 Authors: Siqueira-Lima PS, Quintans JSS, Heimfarth L, Passos FRS, Pereira EWM, Rezende MM, Menezes-Filho JER, Barreto RSS, Coutinho HDM, Araújo AAS, Medrado...
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pubmed: "bioengineered"[jour...Double deletion of murA and murB induced temperature sensitivity in Corynebacterium glutamicum.Related ArticlesDouble deletion of murA and murB induced temperature sensitivity in Corynebacterium glutamicum. Bioengineered. 2019 Oct 24;: Authors: Shi T, Ma Q, Liu X, Hao Y, Li Y, Xu Q, Xie X, Chen N Abstract Currently, the mechanism of temperature-sensitive production of glutamate in Corynebacterium glutamicum has not been clarified. We first found the murA and murB genes...
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pubmed: hpv infection, Application of an entropy-based computational strategy to identify genomic...
pubmed: hpv infection,Application of an entropy-based computational strategy to identify genomic markers for molecular detection and typing of human papillomavirus.Related ArticlesApplication of an entropy-based computational strategy to identify genomic markers for molecular detection and typing of human papillomavirus. Infect Genet Evol. 2019 Oct 23;:104048 Authors: Barros GS, Araujo ED, Santos FLSG, Batista MVA Abstract Human papillomavirus (HPV) is a diverse group of double-stranded DNA viruses...
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Multimodal Technologies and InteractionMTI, Vol. 3, Pages 71: Interaction Order and Historical Body Shaping Children's Making Projects—A Literature ReviewMTI, Vol. 3, Pages 71: Interaction Order and Historical Body Shaping Children's Making Projects—A Literature Review Multimodal Technologies and Interaction doi: 10.3390/mti3040071 Authors: Norouzi Kinnula Iivari The importance of familiarizing children with the Maker Movement, Makerspaces and Maker mindset has been acknowledged. In this literature...
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International Journal of Environmental Research and Public HealthIJERPH, Vol. 16, Pages 4153: Changes in Water Soluble Uremic Toxins and Urinary Acute Kidney Injury Biomarkers After 10- and 100-km RunsIJERPH, Vol. 16, Pages 4153: Changes in Water Soluble Uremic Toxins and Urinary Acute Kidney Injury Biomarkers After 10- and 100-km Runs International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214153 Authors: Wołyniec Kasprowicz Giebułtowicz Korytowska Zorena Bartoszewicz...
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Antioxidants, Vol. 8, Pages 516: CarotenoidsAntioxidants, Vol. 8, Pages 516: Carotenoids Antioxidants doi: 10.3390/antiox8110516 Authors: Volker Böhm Carotenoids are a group of natural pigments, consisting of more than 750 compounds known so far [...]Antioxidants02:00Antioxidants, Vol. 8, Pages 515: Differentiation of Phenolic Composition Among Tunisian Thymus algeriensis Boiss. et Reut. (Lamiaceae) Populations: Correlation to Bioactive ActivitiesAntioxidants, Vol. 8, Pages 515: Differentiation of...
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Does Staged Breast Reduction before Nipple-Sparing Mastectomy Decrease Complications? A Matched Cohort Study between Staged and Nonstaged TechniquesBackground: Nipple-sparing mastectomy in patients with large, ptotic breasts is a reconstructive challenge. Staged breast reduction before prophylactic nipple-sparing mastectomy has been shown to decrease complications; however, a direct comparison of outcomes between staged and nonstaged techniques is lacking. Methods: A retrospective review of all patients...
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RECLASSIFICATION OF FUNDUS AUTOFLUORESCENCE PATTERNS SURROUNDING GEOGRAPHIC ATROPHY BASED ON PROGRESSION RATE: A Systematic Review and Meta-AnalysisShen, Liangbo L.; Liu, Feimei; Nardini, Holly Grossetta; MoreRETINA. 39(10):1829-1839, October 2019.AbstractIn BriefFavorites PDF Get Content & PermissionsPurpose:To reclassify fundus autofluorescence (FAF) patterns around geographic atrophy (GA) based on GA progression rates.Methods:MEDLINE, EMBASE, Cochrane Library, Clinicaltrials.gov , and PubMed...
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CHOROIDEREMIA: Retinal Degeneration With an Unmet NeedPurpose: Choroideremia is an incurable, X-linked, recessive retinal dystrophy caused by loss of function mutations in the CHM gene. It is estimated to affect approximately 1 in 50,000 male patients. It is characterized by progressive degeneration of the retinal pigment epithelium, choroid, and photoreceptors, resulting in visual impairment and blindness. There is an unmet need in choroideremia, because currently, there are no approved treatments...
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Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes(Abstracted from JAMA 2019;321(17):1702–1715) Increased gestational weight gain is associated with higher risk of pregnancy complications, maternal postpartum weight retention, and offspring obesity. It can be caused by maternal fat accumulation, fluid expansion, fetal growth, placental growth, and uterine growth; the weight gain during pregnancy is necessary for a healthy fetus, but the optimal gestational weight gain...
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Does Early Chemotherapy Improve Survival in Advanced Endometrial Cancer?Objectives: In endometrial cancer, the appropriate sequence of adjuvant chemotherapy (aCT) and adjuvant radiation therapy (aRT) is unclear. We aim evaluated whether early chemotherapy is associated with improved overall survival (OS) and cancer-specific survival (CSS). Methods: Endometrial cancer patients that received aCT and aRT were selected from the SEER-Medicare database. Early chemotherapy was defined as receiving aCT before...
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Preface: Functional Fitness and Health Promotion of Older AdultsNo abstract availableFunctional Fitness in Older Adults: A Systematic Review and Meta-analysisBackground: Using multiple interventions can increase muscle strength in older adults. A functional fitness test is a useful instrument to identify the effectiveness of physical functioning among older adults. However, the results in previous studies with regard to improvements in their physical function are inconsistent. Aim: To synthesize...
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A Multicenter, Randomized, Double-blind, Parallel, Placebo-controlled Clinical Study to Evaluate the Efficacy and Safety of a Nicotine Mint Lozenge (2 and 4 mg) in Smoking CessationObjective: To evaluate the efficacy in smoking cessation and safety of 2 and 4 mg nicotine mint lozenges in Chinese adult smokers. Methods: This was a multicenter, randomized, stratified, double-blind, placebo-controlled, parallel-group study. The low-dependence stratum included 483 smokers (241 randomized to active 2 mg...
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Fischerella thermalis : a model organism to study thermophilic diazotrophy, photosynthesis and multicellularity in cyanobacteriaAbstractThe true-branching cyanobacterium Fischerella thermalis (also known as Mastigocladus laminosus) is widely distributed in hot springs around the world. Morphologically, it has been described as early as 1837. However, its taxonomic placement remains controversial. F. thermalis belongs to the same genus as mesophilic Fischerella species but forms a monophyletic clade...
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Parálisis vocal, logopedia y análisis acústico. Estudio de resultados de 43 pacientesPublication date: Available online 14 September 2019Source: Revista de Logopedia, Foniatría y AudiologíaAuthor(s): Miguel Alberto Rodríguez Pérez, José Francisco Delgado Álvarez, Carmen Castillo Requena, Francisco Sabido Martín, Eulalia Porras Alonso, Carmen Salom CoveñasResumenIntroducción y objetivosConsideramos que existe patología vocal cuando apreciamos anomalías en el tono, volumen y/o calidad de emisión que...
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An update on autoimmune inner ear disease: A systematic review of pharmacotherapy☆☆☆Author links open overlay panelDavidStrumSunnyKimTimothyShimAshkanMonfaredDivision of Otolaryngology-Head and Neck Surgery, George Washington University, 2300 M St NW, 4th floor, Washington, DC 20037, United StatesReceived 26 September 2019, Available online 28 October 2019.Show lesshttps://doi.org/10.1016/j.amjoto.2019.102310Get rights and contentHighlights•There is insufficient data from randomized-controlled trials...
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Immobilization efficiency and mechanism of metal cations (Cd2+, Pb2+ and Zn2+) and anions (AsO43- and Cr2O72-) in wastes-based geopolymerPublication date: 15 February 2020Source: Journal of Hazardous Materials, Volume 384Author(s): Zehua Ji, Yuansheng PeiAbstractIn this study, a composite geopolymer based on solid wastes (drinking water treatment residue (DWTR) and granulated blast furnace slag (GBFS)) were used in immobilization of heavy metals cations (Cd2+, Pb2+ and Zn2+) and anions (AsO43− and...
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Volcanism and paleoenvironment of the pula maar complex: A pliocene terrestrial fossil site in Central Europe (Hungary)Publication date: 1 January 2020Source: Palaeogeography, Palaeoclimatology, Palaeoecology, Volume 537Author(s): János Kovács, Károly Németh, Péter Szabó, László Kocsis, Gábor Kereszturi, Gábor Újvári, Torsten VennemannAbstractWe describe the Late Pliocene paleoenvironment and paleoclimate of the Pula fossil site of the western Pannonian Basin, Hungary, which occurs within a lacustrine...
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Extracorporeal Membrane Oxygenation Support After Heart Transplantation in Children—Outcomes of a Single Center CohortObjectives: Extracorporeal membrane oxygenation is used for postcardiotomy low cardiac output but is less established following heart transplantation. We characterized outcomes for children supported with extracorporeal membrane oxygenation after heart transplantation. Design: Single-center retrospective study. Setting: Large pediatric cardiac referral center. Patients: All patients...
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Vaccines, Vol. 7, Pages 162: Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis...Vaccines, Vol. 7, Pages 162: Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c MiceVaccines, Vol. 7, Pages 162: Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice Vaccines...
Mon Oct 28, 2019 13:19
Vaccines, Vol. 7, Pages 162: Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis...Vaccines, Vol. 7, Pages 162: Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c MiceVaccines, Vol. 7, Pages 162: Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice Vaccines...
Mon Oct 28, 2019 13:19
Vaccines, Vol. 7, Pages 162: Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis...Vaccines, Vol. 7, Pages 162: Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c MiceVaccines, Vol. 7, Pages 162: Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice Vaccines...
Mon Oct 28, 2019 13:19
Effectiveness of the virtual reality on cognitive function of children with hemiplegic cerebral palsy: a single-blind randomized controlled trialCerebral palsy is a term covering non-progressive motor and cognitive impairments caused by lesions of the brain. This study aims to evaluate the effectiveness of virtual reality-based rehabilitation program for children with hemiplegic cerebral palsy on cognitive functions. Ninety children (47 boys, 43 girls) with hemiplegic cerebral palsy were randomized...
Mon Oct 28, 2019 13:19
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,