Why What You May Not Know About Fecal Immunochemical Testing Matters

In this issue, Imperiale and colleagues report a systematic review that included 31 studies involving 120 255 patients and concluded that single-application fecal immunochemical tests (FITs) have moderate to high sensitivity and specificity for colorectal cancer (CRC), depending on the positivity threshold. The editorialist discusses why these findings, combined with other evidence, should help to reassure physicians and patients about the performance of FITs for CRC detection.

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