Whole-genome sequencing identifies ADGRG6 enhancer mutations and FRS2 duplications as angiogenesis-related drivers in bladder cancer
Whole-genome sequencing identifies <i>ADGRG6</i> enhancer mutations and <i>FRS2</i> duplications as angiogenesis-related drivers in bladder cancer, Published online: 12 February 2019; doi:10.1038/s41467-019-08576-5
Bladder cancer is one of the most common and highly vascularized cancers. Here the authors perform a whole-genome analysis in urothelial bladder carcinomas and identify recurrent genetic alterations in a set of angiogenesis genes, facilitating the understanding of molecular mechanisms underlying pathological angiogenesis in this type of cancer.from A via a.sfakia on Inoreader https://go.nature.com/2N0nQd6
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,