Whole-genome sequencing identifies ADGRG6 enhancer mutations and FRS2 duplications as angiogenesis-related drivers in bladder cancer

Whole-genome sequencing identifies ADGRG6 enhancer mutations and FRS2 duplications as angiogenesis-related drivers in bladder cancer

Whole-genome sequencing identifies <i>ADGRG6</i> enhancer mutations and <i>FRS2</i> duplications as angiogenesis-related drivers in bladder cancer, Published online: 12 February 2019; doi:10.1038/s41467-019-08576-5

Bladder cancer is one of the most common and highly vascularized cancers. Here the authors perform a whole-genome analysis in urothelial bladder carcinomas and identify recurrent genetic alterations in a set of angiogenesis genes, facilitating the understanding of molecular mechanisms underlying pathological angiogenesis in this type of cancer.

from A via a.sfakia on Inoreader https://go.nature.com/2N0nQd6