Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis

Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis

Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis, Published online: 30 January 2019; doi:10.1038/s41467-019-08387-8

Lineage segregation from conception to gastrulation has been mapped at the single cell level in mouse, human and monkey. Here, the authors provide a comprehensive analysis of porcine preimplantation development using single cell RNA-seq; mapping metabolic changes, X chromosome inactivation and signalling pathways.

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