Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells

Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells

Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells, Published online: 30 January 2019; doi:10.1038/s41467-019-08378-9

The precise cellular patterning and decisions of early embryogenesis have been hard to mimic in vitro. Here, the authors culture murine embryonic and trophoblast stem cells together with extra-embryonic endoderm stem cells to form embryo-like structures (ETX-embryoids), which can initiate an implantation response.

from A via a.sfakia on Inoreader https://go.nature.com/2WpTRzH