The n-HA/PA66 cage versus the PEEK cage in anterior cervical fusion with single-level discectomy during 7 years of follow-up.

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The n-HA/PA66 cage versus the PEEK cage in anterior cervical fusion with single-level discectomy during 7 years of follow-up.

World Neurosurg. 2018 Dec 18;:

Authors: Hu B, Yang X, Hu Y, Lyu Q, Liu L, Zhu C, Zhou C, Song Y

Abstract
OBJECTIVE: The nano-hydroxyapatite/polyamide66 (n-HA/PA66) cageis a novel biomimetic non-metal cage, while the polyetheretherketone (PEEK) cage has been widely used for decades with excellent clinical outcomes. However, there has been no long-term comparison of these two cages in anterior cervical reconstruction.
PATIENTS AND METHODS: This retrospective study included 98 patients who underwent single-level anterior cervical decompression and fusion (ACDF) from January2009to June 2011with at least 7 years of follow-up; the PEEK cage was used in 51 patients (PEEK group), while the n-HA/PA66 cage was used in 47 (n-HA/PA66 group). The groups were compared regarding radiographic (cage subsidence, fusion status, cervical lordosis, and segmental sagittal alignment) and clinical (VAS and JOA scores) parameters preoperatively, postoperatively, and at final follow-up.
RESULTS: The n-HA/PA66 and PEEK cages had similar fusion rates at final follow-up (97.9% vs98.0%). The respective cage subsidence rates in the PEEK and n-HA/PA66 cage groups were 9.8% and 10.6%. There were no significant differences between the two groups in mean cervical lordosis, mean interbody height, segmental sagittal alignment, cervical lordosis, and VAS and JOA scores at final follow-up. The n-HA/PA66 cages resulted in high fusion and low subsidence rates during long-term follow-up.
CONCLUSIONS: After single-level ACDF, the n-HA/PA66 cage showed similar radiographic fusion, subsidence rate and clinical results compared with the PEEK cage during 7 years of follow-up. These results suggest that the n-HA/PA66 cage could be comparable to the PEEK cage for ACDF.

PMID: 30576825 [PubMed - as supplied by publisher]

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