IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses

IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses

IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses, Published online: 20 December 2018; doi:10.1038/s41467-018-07762-1

IgSF9b is a synaptic adhesion protein that has been linked to psychiatric disorders. Here the authors show that deletion of IgSF9b regulates anxiety-like behaviour in mice by increasing inhibitory synaptic transmission in the centromedial amygdala.

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