In their article, Ioannidis and colleagues raise several important issues concerning the potential misuse and misinterpretation of the E-value, a metric related to the robustness of associations to potential unmeasured or residual confounding. The editorialists discuss the usefulness of the E-value in practice in response to practical objections sometimes raised to other sensitivity analysis techniques that they are too complicated to describe in papers, are too difficult to present, take up too much space, and are difficult to understand.
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,