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Τρίτη 11 Δεκεμβρίου 2018

Amidyl Radical Directed Remote Allylation of Unactivated sp3 C‐H Bonds via Organic Photoredox Catalysis

The development of visible‐light‐mediated allylation of unactivated sp3 C‐H bonds is reported. The remote allylation was directed by the amidyl radical, which was generated by photocatalytic fragmentation of a pre‐functionalized amide precursor. Both aromatic and aliphatic amide derivatives could successfully deliver the remote C‐H allylation products in good yields. A variety of electron deficient allyl sulfone systems could be used as δ‐carbon radical acceptor.



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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,

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