Evaluation of Tier One Exposure Assessment Models (ETEAM): Project Overview and Methods

Within the European Union, the Registration, Evaluation, Authorisation and restriction of Chemicals (REACH) Regulation (European Parliament, 2006) requires the registration of chemical substances which are manufactured or imported in amounts of 1 tonne or more per year. If the substance being registered is manufactured or imported in quantities of 10 tonnes or more per year, registrants must undertake a chemical safety assessment (CSA) and complete a chemical safety report (CSR). For classified substances, the CSA has to include an exposure assessment for all identified uses. Several computer-based tools are mentioned in the European Chemicals Agency (ECHA) REACH guidance (ECHA, 2012, 2016) as being suitable for assessing worker exposure within the substance registration process. These tools vary in area of application, level of detail and outputs, from simple screening tier 1 tools, which are designed to easily and quickly differentiate those situations that may pose a risk to health from those which do not, to more advanced, higher level tools that should give a more refined and accurate estimate of exposure (for example, Advanced REACH Tool, 2013). Tool predictions are used to identify, iterate, and verify the risk management measures (RMMs) required to control exposure in workplaces, with this information distributed to substance users via the supply chain.

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