Objectives: Myxofibrosarcoma (MFS) is reported to have a higher risk of local recurrence (LR) following definitive surgical excision relative to other soft tissue sarcomas. We reviewed our clinical experience treating MFS to investigate predictors of LR. Materials and Methods: We retrospectively reviewed treatment outcomes for MFS patients treated at our institution between 1999 and 2015. A total of 52 patients were identified. Median age was 65 years (range, 21 to 86 y). Site of disease was: upper extremity (27%), lower extremity (46%), trunk (15%), pelvic (8%), and head and neck (4%). Patients had low, intermediate, high-grade, and unknown grade in: 23%, 8%, 67%, and 2% of tumors, respectively. Tumors were categorized as 5 cm (56%), or unknown size (9%). In total, 71% received radiotherapy: 19% preoperative, 50% postoperative, and 2% both. All patients underwent surgery. Margins were negative in 71%, close/positive in 21%, and unknown in 8%. In total, 27% of patients received chemotherapy. Univariate Cox regression analysis was utilized to determine associations between clinical and treatment factors with LR. Results: Median follow-up time was 2.9 years (range, 0.4 to 14.3 y). The 3-year actuarial LR, distant metastasis, and overall survival were: 31%, 15%, and 87%, respectively. Predictors of LR were patient age greater than or equal to the median of 65 years (hazard ratio, 13.46, 95% confidence interval, 1.71-106.18, P=0.013), and having close/positive tumor margins (hazard ratio, 3.4, 95% confidence interval, 1-11.53, P=0.049). Conclusions: In this institutional series of MFS older age and positive/close margins were significantly associated with a higher risk of LR. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.
from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/2seYukE
from ! Medicine by Alexandros G. Sfakianakis via alwin on Inoreader http://ift.tt/2tVGSre
via IFTTT
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Αρχειοθήκη ιστολογίου
-
►
2023
(272)
- ► Φεβρουαρίου (141)
- ► Ιανουαρίου (131)
-
►
2022
(2066)
- ► Δεκεμβρίου (80)
- ► Σεπτεμβρίου (170)
- ► Φεβρουαρίου (190)
- ► Ιανουαρίου (203)
-
►
2021
(7399)
- ► Δεκεμβρίου (186)
- ► Σεπτεμβρίου (472)
- ► Φεβρουαρίου (851)
-
►
2020
(2517)
- ► Δεκεμβρίου (792)
- ► Σεπτεμβρίου (21)
- ► Φεβρουαρίου (28)
-
►
2019
(12076)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (4765)
- ► Ιανουαρίου (5155)
-
►
2018
(3144)
- ► Δεκεμβρίου (3144)
-
▼
2017
(66935)
- ► Δεκεμβρίου (1995)
- ► Σεπτεμβρίου (12424)
-
▼
Ιουνίου
(12984)
-
▼
Ιουν 27
(439)
- The Complexity of Simple – Bringing Order to Compl...
- A population level atlas of Mus musculus craniofac...
- Rheumatoid nodule on cytology
- Rheumatoid nodule on cytology
- Sculptors, Architects, and Painters Conceive of De...
- Working night shifts reduces repair of DNA damage,...
- Microneedle patch for flu vaccination proves succe...
- Working night shifts reduces repair of DNA damage,...
- Microneedle patch for flu vaccination proves succe...
- Ixazomib: A Review in Relapsed and/or Refractory M...
- Relationship between obstructive sleep apnea and n...
- Mohs Mapping Fidelity: Optimizing Orientation, Acc...
- Detection of High-Risk Histologic Features and Tum...
- Microcystic adnexal carcinoma (MAC) is a rare, loc...
- Chemotherapy-induced cardiomyopathy caused by Peme...
- The Traumatic Brain Injury Endpoints Development (...
- Three Year Trends in Veterans Health Administratio...
- Neurodegeneration in the Spinal Ventral Horn Prior...
- A novel strategy with combined assays for detectio...
- Unique Infectious Strategy of H5N1 Avian Influenza...
- Relationship between obstructive sleep apnea and n...
- The Breast Cancer Screening “Arcade” and the “Whac...
- Neurodegeneration in the Spinal Ventral Horn Prior...
- The Traumatic Brain Injury Endpoints Development (...
- CASE STUDY: Amber & Fred
- Three Year Trends in Veterans Health Administratio...
- Second-line Agents in Pediatric Patients With Auto...
- Characterizing and Defining “Infantile Liver Failure”
- Allergic Interstitial Nephritis Masquerading as Py...
- Pediatric Autoimmune Hepatitis: What Do You Do Whe...
- Intestinal Metaplasia of the Esophagus in Children...
- Twelve Novel Mutations in the SLC26A3 Gene in 17 S...
- Early Empiric Antibiotic Use Is Associated With De...
- Biomarkers of Environmental Enteric Dysfunction: T...
- Low Hepatic Tissue Copper in Pediatric Nonalcoholi...
- Giant Pelvic Cyst in 16-Year-Old Boy With Bloody D...
- Eosinophilic Esophagitis and Celiac Disease: A Tru...
- Treatment of Functional Abdominal Pain With Antide...
- Increased Fat Absorption From Enteral Formula Thro...
- Yield of Endoscopy in Pediatric Gastroparesis
- Commercial Probiotic Products: A Call for Improved...
- Age and Sex Normalization of Intestinal Permeabili...
- Apropos: “Gut Microbiota Differences in Children F...
- Biomarkers of Environmental Enteric Dysfunction Am...
- Outpatient Liver Biopsy in Children: Safety, Feasi...
- Filaggrin and Periostin Expression Is Altered in E...
- Efficacy of Sequential Ipilimumab Monotherapy vs B...
- First-in-Human Study of AMG 820, a Monoclonal Anti...
- Diffusion MRI phenotypes predict overall survival ...
- To the Editor.
- Update on Treatment Options for Advanced Bile Duct...
- Effect of Cocoa Polyphenolic Extract on Macrophage...
- Orderly Roulette Selection Based Ant Colony Algori...
- Ubiquitous and Seamless Localization: Fusing GNSS ...
- Everolimus Implicated in Case of Severe Gastrointe...
- Quadratus Lumborum Spares Paravertebral Space in F...
- A Novel Two-Disc Machine for High Precision Fricti...
- Sensor Network Disposition Facing the Task of Mult...
- Study on Cutting Form and Surface Machining Qualit...
- Filter Design for Continuous-Time Linear Systems S...
- Method of Improved Fuzzy Contrast Combined Adaptiv...
- Enhanced Recovery After Surgery: Current Controver...
- Study on the Gap Flow Simulation in EDM Small Hole...
- Role of Vascular Endothelial Cells in Disseminated...
- Design and Development Framework of Safety-Critica...
- Activated Carbon Fiber Monoliths as Supercapacitor...
- Effect of Varying the Semiconducting/Metallic Tube...
- A Case of Strongyloidiasis: An Immigrant Healthcar...
- The Antidepressant and Cognitive Improvement Activ...
- Performance Analyses of the Radio Orbital Angular ...
- A New Method to Optimize the Wake Flow of a Vehicl...
- Imaging Guidance for Thoracic Epidural Catheter Pl...
- In Response.
- In Response.
- A phase Ib study of pembrolizumab plus chemotherap...
- Validation of a Real-Time Minute-to-Minute Urine O...
- To the Editor.
- In Response.
- In Response.
- An Automated Critical Event Screening and Notifica...
- Anesthetic Management of Narcolepsy Patients Durin...
- Loss of Resistance Syringe: A Substitute for Cuff ...
- Recommendations for Procedural Sedation Clinical T...
- Dural Puncture Epidural Technique: Not So Fast.
- Intraoperative Detection of Persistent Endoleak by...
- MicroRNA-211-5p suppresses tumour cell proliferati...
- Inhibition of Androgen Receptor Nuclear Localizati...
- MicroRNA-7 suppresses the homing and migration pot...
- Phase II study of neoadjuvant imatinib in large ga...
- ADA-07 suppresses solar ultraviolet-induced skin c...
- Inhibition of Megakaryocyte Differentiation by Ant...
- Frozen shoulder and risk of cancer: a population-b...
- A small molecule inhibitor of WEE1, AZD1775, syner...
- Second-line pazopanib in patients with relapsed an...
- CBF1 is clinically prognostic and serves as a targ...
- Randomised controlled trial of early prophylactic ...
- A meta-analysis of CXCL12 expression for cancer pr...
- Hallmarks of response to immune checkpoint blockade
- High-energy particle beam and gamma radiation expo...
- Oncolytic alphavirus SFV-VA7 efficiently eradicate...
-
▼
Ιουν 27
(439)
Ετικέτες
Πληροφορίες
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Αναζήτηση αυτού του ιστολογίου
! # Ola via Alexandros G.Sfakianakis on Inoreader
-
Publication date: 1 May 2019 Source: Talanta, Volume 196 Author(s): Ruiqing Long, Te Li, Chaoying Tong, Lihui Wu, Shuyun Shi Abstract...
-
Oral Cancer Rapid Test Kit Market Rugged Expansion Foreseen by 2024 MilTech Oral cancer is one of the largest group of cancers ...
-
Related Articles SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,